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Proteinase-activated receptor 2 (PAR-2) is a G protein-coupled receptor related to the thrombin receptor. PAR-2 can be activated by trypsin and by synthetic peptides corresponding to the new amino terminus generated by activating proteolytic cleavage. We show in this report that intravenous injection of PAR-2 agonist peptides has dramatic effects on arterial blood pressure in anesthetized rats. Th
The article presents the outlines of an integrative theory of meaning based on the concept of value, understood both as a biological and as a socio-cultural category, synthesizing ideas from evolutionary and developmental psychology, semiotics and cybernetics. The proposal distinguishes between four types of meaning systems, cue-based, associational, mimetic and symbolic, forming an evolutionary a
Atmospheric deposition of N and S appears to have caused nutrient imbalance in Norway spruce stands in southern Sweden. This calls for a change of forest management to procedures that promote nutrient balance. Studies have shown lower soil acidity in Norway spruce/deciduous mixed stands than in spruce monocultures, but the tree nutrient status in such mixtures has not been much investigated so far
The cyclisation conditions for the formation of bicyclo[2.2.2]octan-2,6-di one (1) from 3-substituted cyclohexanones 2 and 3 have been re-investigated. Use of a medium consisting of isobutyric anhydride and trifluoroacetic acid resulted in a simplified and reproducible method for large-scale synthesis of this compound.
The aim of this study was to investigate the effect of training on the in vivo tibial structural strength during the development of post-ovariectomy osteoporosis. Seventeen mature Wistar rats (215 g) were ovariectomized and randomized into two groups. The sedentary control group was kept cage confined, while 3 days postoperatively the trained group started treadmill running with high intensity for
Archaeology has become a potent element in themed environments that abound in contemporary popular culture. This short article reviews the archaeological motifs that can be found in environments such as Disneyland and on the Las Vegas Strip. They provide a set of imagery to which people can easily relate and that immerses them in a world different from the normal routines and restrictions of every
Data from full scale experiments are collected and organized in a database. A statistical method is developed to evaluate the uncertainty in predictions of smoke transport models. The method is based on a regression analysis of measured and predicted data. The computer program CFAST is evaluated to exemplify the statistical method. The uncertainty is quantified with a regression coefficient and th
Emanuel Swedenborg and the covert enlightenment
Popular Abstract in Swedish Beräkningar med detaljerade kemiska reaktionssytem, med uppemot 1500 kemiska reaktioner, har utförts på HCCI-motorer, en experimentell motortyp som bygger på homogen kompressionsantändning. Resultaten jämfördes med experimentella mätningar och visade att beräkningar med god noggrannhet kan utföras, men att antändingsprocessen är mycket känslig för även små variationer iCalculations on a Homogeneous Charge Compression Ignition (HCCI) engine have been performed. Zero-dimensional models were used. The simplest model compressed the gas to auto-ignition, using temperature and pressure at a certain crank angle position obtained from engine experiments. It was found that calculations with good agreement could be accomplished, if using correct temperature, pressure and
Properties of simple strategies for swinging up an inverted pendulum are discussed. It is shown that the behavior critically depends on the ratio of the maximum acceleration of the pivot to the acceleration of gravity. A comparison of energy-based strategies with minimum time strategy gives interesting insights into the robustness of minimum time solutions.
