Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the management of bone defects caused by trauma or various orthopedic conditions including, but not limited to, infections and tumours. Bone grafts are a surgeon’s choice, but their associated drawbacks are paving the way for biomaterial based bone graft substitutes. Biomaterials inherently lack the ability to induce s

Semiconductor nanowires have proven to be promising building blocks for next-generation optoelectronic devices. The nanometric dimensions of nanowires provides strain relaxation capability, thus enabling the heteroepitaxy of III-V materials on silicon, as well as providing the possibility of realizing optoelectronic devices with lattice-mismatched material combinations. The subwavelength dimension

I den här avhandlingen studeras styrning av välfärdssamverkan, med focus på betydelsen av kunskap i styrning. I offentlig verksamhet – och i välfärd i synnerhet – är samverkan mellan myndigheter, kommunala förvaltningar och välfärdsprofessionella ett återkommande sätt att hantera olika problem som de traditionella offentliga institutionerna anses oförmögna att lösa. Genom att studera ett specifiktThis dissertation analyses how welfare collaboration is governed, focusing on the role of knowledge in government. In the public sector – and in welfare especially – collaboration between agencies, municipal departments and welfare professions is a recurring response to various problems where the traditional public-sector institutions are considered inapt to provide solutions. By studying a specif

Johannes Magnus (1488–1544) was the last Catholic archbishop of Uppsala to hold residence in Sweden. He was also an historian and wrote a major work on Swedish history, the Historia de omnibus Gothorum Sueonumque regibus, which was published posthumously in Rome in 1554. The work eventually became the ideological foundation for Swedish patriotism in the 17th century. The Historia de regibus places

This paper presents an in-depth manufacturing cost analysis of conventional wrought steel gear manufacturing and a case study of a spur engine gear is evaluated by real usage data, including a benchmark in gear manufacturing cost calculations between the participating company cost calculation method and the model used and developed in this research. The applicability of the developed manufacturing

In the last few decades it has become ever clearer that humankind faces many serious environmental challenges. As the corporate sector has been identified as an important actor to address these challenges, understanding why certain companies choose to adopt sustainability initiatives, while others do not, is an important question. However, little previous research has addressed how sustainability

Lung cancer accounts for 1.6 million cancers annually and 1.3 million deaths per year make the disease the deadliest type of cancer. Smoking is the most prominent cause. High mortality rates are partly due to late diagnosis which limits the therapy options. Improved understanding of molecular and biological mechanisms of tumor development could guide current therapy selection or pave way for novelLung cancer accounts for 1.6 million cancers annually and 1.3 million deaths per year make the disease the deadliest type of cancer. Smoking is the most prominent cause. High mortality rates are partly due to late diagnosis which limits the therapy options. Improved understanding of molecular and biological mechanisms of tumor development could guide current therapy selection or pave way for novel

Långdistansflyttande fåglar uppvisar ett flertal gemensamma egenskaper som ger dem goda förutsättningar att regelbundet förflytta sig över kontinentala avstånd. De har exempelvis en effektiv flygmotor som gör att de kan hålla sig flygande, och en god förmåga att både lägga på sig, och bränna fett som flygbränsle. Fåglar uppvisar i regel också goda orienterings- och navigationsegenskaper, vilket ärMany birds are predisposed to annually undertake movements over large temporal and spatial scales. They have an efficient flight machinery, demonstrate impressive capacities in storing and burning fuel, and they exhibit necessary orientation and navigational skills. Avian migrants are still limited in the amount of time and energy they can allocate towards their movements and need to balance migra

We present a theory of molecular motors based on the Ehrenfest dynamics for nuclear coordinates and the adiabatic limit of the Kadanoff-Baym equations for current-induced forces. Electron-electron interactions can be systematically included through many-body perturbation theory, making the nonequilibrium Green's function formulation suitable for first-principles treatments of realistic junctions.

Mechanisms of injury and repair in alveolar epithelial cells (AECs) are critically involved in the progression of various lung diseases including idiopathic pulmonary fibrosis (IPF). Homeobox only protein x (HOPX) contributes to the formation of distal lung during development. In adult lung, alveolar epithelial type (AT) I cells express HOPX and lineage-labeled Hopx+ cells give rise to both ATI an

Sound physical health is a critical component of the human development process, wherein early life and childhood are pivotal periods. Although child health in sub-Saharan Africa has been improving for the past few decades, the region still has the highest mortality rate for children under five as well as high levels of child morbidity. The most immediate causes of these poor health outcomes are in

How temperature influences development has direct relevance to ascertaining the impact of climate change on natural populations. Reptiles have served as empirical models for understanding how the environment experienced by embryos can influence phenotypic variation, including sex ratio, phenology and survival. Such an understanding has important implications for basic eco-evolutionary theory and c

Attosecond pulses are short enough to capture the electronic dynamics in atoms and molecules. The work presented in this thesis deals with the generation and optimization of attosecond extreme-ultraviolet (XUV) pulses. The goal is to progress towards the realization of time-resolved nonlinear experiments at the intense XUV beamline of the Lund High-Power Laser Facility.The XUV flux was optimized u

Aims/hypothesis: Coronary artery disease (CAD) is a common complication among individuals with diabetes. A better understanding of the genetic background of CAD in this population has the potential to suggest novel molecular targets for screening, risk assessment and drug development. Methods: We performed a genome-wide association study of CAD in 15,666 unrelated individuals (3,968 CAD cases and

In the primary school classroom, children are exposed to multiple factors that combine to create adverse conditions for listening to and understanding what the teacher is saying. Despite the ubiquity of these conditions, there is little knowledge concerning the way in which various factors combine to influence listening comprehension and the effortfulness of listening. The aim of the present study

Planning and execution of large infrastructure projects benefit from detailed mapping of the subsurface through geophysical methods. However applying geophysical methods in an urban environment requires careful preparation to ensure success in areas where source of noise and present infrastructure may compromise the results. We present and discuss the results of a seismic investigation conducted i

Artikeln behandlar översiktigt arkitektur, porträttkonst, makt och historiebruk från Gustav Vasa till drottning Kristina. I den görs också utvikningar som relaterar den svenska utvecklingen inom området till den på kontinenten. En sammanfattning av övergången från medeltid till renässans till i Sverige ingår liksom en utblick på vad som sker inom arkitekturen i Skåne som vid tiden var danskt, samt