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A healthy brain is associated with a longer life, while ageing is the greatest risk factor for neurodegenerative diseases such as Alzheimer’s and Parkinson’s. But what distinguishes healthy ageing from disease-related ageing? It is a complex question that researchers are working to answer. "We know a great deal about how age affects brain function, but we know virtually nothing about the underlyin
https://www.stemcellcenter.lu.se/news/community-voices/ageing-brain - 2026-08-11
By freezing your own healthy blood stem cells in your twenties, thawing them out, and undergoing a stem cell transplant in your forties or fifties, it might be possible to rejuvenate your blood-forming system and immune system. Science fiction? At least it works when old mice receive new healthy blood stem cells from young mice. Mice live only a couple of years at most. That makes them suitable to
https://www.stemcellcenter.lu.se/news/community-voices/stem-cell-transplantation-key-healthier-ageing - 2026-08-11
– A PhD Defense Interview with Christina-Anastasia Stamouli For Christina-Anastasia Stamouli, an interest in biology, genetics, and the molecular foundations of life began early, and led her to journey from Greece to Lund to pursue a PhD. At Lund University, her research has focused on generating human interneurons for cell replacement and disease modelling to better understand and treat neurologi
Gribonika Group Our researchDefined physical borders are not only set between countries, but also between our living self and the outside environment. Our body’s borders are the mucocutaneous barrier organs such as the skin and the gut that are the very first battlefields when facing an infection or injury. Of note, every barrier organ is also inhabited by a diverse community of beneficial microbe
https://www.stemcellcenter.lu.se/research-groups/Gribonika - 2026-08-11
3 September 2026 08:30 | Thesis defence Qi Wang, a doctoral student in the Translational Lung Transplantation and Lung Cell Therapy Research Group led by Associate Professor Sandra Lindstedt, is set to defend their thesis on Thursday, September 3rd, 2026 at 8:30. Dissertation title: 'From Tissue to Insight: Advanced Tissue Processing and Spatial Imaging in Translational Lung Transplantation'Main s
https://www.stemcellcenter.lu.se/calendar/phd-defence-qi-wang-subject-medical-science - 2026-08-11
24 September 2026 09:00 | Thesis defence Niklas Segrén, a doctoral student in the Developmental Immunology Research Group led by Associate Professor Joan Yuan, is set to defend his thesis on Thursday, September 24th, 2026 at 9:00. Dissertation title: 'On the Early Origin of B Cells'Main supervisor: Associate Professor Joan YuanOpponent: Professor Lars Nitschke, Erlangen-NurembergChairman of the pu
https://www.stemcellcenter.lu.se/calendar/phd-defence-niklas-segren-subject-medical-science-immunology-medical-field - 2026-08-11
– A PhD Interview with Ninoslav Pandiloski Nearly half of the human genome consists of repetitive DNA, once dismissed as “junk.” During his time as a doctoral student at Lund University’s Lund Stem Cell Center, Ninoslav Pandiloski combined epigenetics, stem cell models, and bioinformatics to study these repetitive DNA sequences, known as transposable elements, and their role in human brain develop
https://www.stemcellcenter.lu.se/epigenetic-regulation-transposable-elements-human-brain-development-and-disease - 2026-08-11
StemTherapy Funding Initiatives Technology Implementation Grants support the integration of advanced technologies and shared research infrastructure within StemTherapy, enabling new experimental approaches and strengthening research capacity across the Center. Call Details: StemTherapy Technology Hubs and Shared Research Infrastructure or Equipment Deadline: 30th September 2026Funding period: Up t
https://www.stemcellcenter.lu.se/about/stemtherapy-funding-initiatives/technology-implementation-grants - 2026-08-11
The Scientific Advisory Board (SAB) is an international team of esteemed researchers in the fields of basic and translational stem cell research. Comprised of experts from top research institutions around the world, the SAB provides invaluable strategic advice and recommendations to the Lund Stem Cell Center's Steering Group and Management Team.As a key part of the Center's leadership structure, t
https://www.stemcellcenter.lu.se/lund-stem-cell-center/stemtherapy-scientific-advisory-board - 2026-08-11
S. Karlsson Group Our ResearchWe are studying the regulation of hematopoietic stem cells (HSCs) in order to understand how signaling pathways, transcriptional mechanisms and epigenetic regulators govern stem cell behavior to determine stem cell fate options.Integrative signaling and transcriptional networks act in concert to determine whether hematopoietic stem cells remain quiescent, proliferate
https://www.stemcellcenter.lu.se/research-groups/skarlsson - 2026-08-11
Larsson Group Our researchThe focus of the research in the Larsson group is to define genes and pathways that regulate human hematopoietic stem cells (HSCs) and to develop novel strategies for ex vivo stem cell expansion to enhance current cell therapies of hematological disorders. Over the last few years the laboratory has developed strategies to screen for modifiers of self-renewal/proliferation
https://www.stemcellcenter.lu.se/research-groups/larsson - 2026-08-11
Researchers at Lund University already have a strong international position in two major areas of somatic stem cell and cell therapy research: Neural cell replacement therapies for central nervous system (CNS) disorders Hematopoietic stem cell (HSC) biology and gene therapyThe sections of Neurobiology and Restorative Neurology have an internationally leading position in CNS disease models and expe
https://www.stemcellcenter.lu.se/research - 2026-08-11
Artner Group Our Research Diabetes results from loss or dysfunction of insulin producing beta cells in the pancreas. Despite insulin injection treatment, diabetic patients suffer from long-term complications, such as blindness and kidney failure. Therefore, a central goal of diabetes research is to regenerate pancreatic beta cells or produce large numbers of functional beta cells for transplantati
https://www.stemcellcenter.lu.se/research-groups/artner - 2026-08-11
Pera Group Our Research In our research, we are studying extracellular signals in embryonic development and cancer. Particular emphasis is given to mechanisms that regulate pattern formation and collective cell migration in the vertebrate embryo. The neural crest is a multipotent and highly motile cell population that arises at the border of the neural plate, delaminates and colonizes a wide varie
https://www.stemcellcenter.lu.se/research-groups/pera - 2026-08-11
Pronk Group Our ResearchToday, we cure about 85% of children with cancer. In some subgroups, such as acute lymphoblastic leukemia (ALL), cure rates exceed 90%. Treating pediatric cancer patients is characterized by balancing of anti-tumor actions with treatment related morbidity/mortality. Many patients suffer from treatment toxicities during or following completion of treatment, sometime with a l
https://www.stemcellcenter.lu.se/research-groups/pronk - 2026-08-11
Rönnstrand Group Our ResearchThe focus of our laboratory is to understand the molecular mechanisms of cancer, specifically acute leukemia and malignant melanoma. In particular, in acute myeloid leukemia, oncogenic mutations in the receptor tyrosine kinase FLT3 is commonly occurring and correlates with poor prognosis of patients. For this reason, several selective inhibitors of FLT3 have been devel
https://www.stemcellcenter.lu.se/research-groups/ronnstrand - 2026-08-11
Scheding Group Our researchHuman bone marrow (BM) contains the hematopoietic stem cells (HSC) as well as a rare population of non-hematopoietic bone marrow stromal stem cells (BMSC). The HSCs are responsible for the life-long production of the different blood cells, whereas BMSCs generate skeletal tissues and give rise to the hematopoietic microenvironment (HME).HSC and BMSC closely interact with
https://www.stemcellcenter.lu.se/research-groups/scheding - 2026-08-11
Soneji Group Thousands of single-cells can be profiled using next generation sequencing technologies, and this leads to a massive amount of data which needs processing and analysing to determine the underlying biology of the samples assayed. Key to this is data visualisation, and a common step is to generate "maps" of cells which make the data human-comprehensible. The maps are often constructed i
https://www.stemcellcenter.lu.se/research-groups/soneji - 2026-08-11
Wagner Group Our research Over three million people die each year and over 60 million people suffer worldwide from chronic lung diseases (CLDs). Currently, there is no cure for CLDs, including chronic obstructive pulmonary disease (COPD), pulmonary hypertension, and pulmonary fibrosis. Lung transplantation is the only option at end-stage disease and is further complicated by shortage in organs ava
https://www.stemcellcenter.lu.se/research-groups/wagner - 2026-08-11
Woods Group Our ResearchHematopoietic stem cells (HSCs) are rare cells in the body that possess the ability to generate vast numbers of a multitude of specialised blood cell types required for our survival. HSCs are first generated in the early embryo and undergo a series of maturation processes that ultimately give rise to their key adult features of self-renewal, blood cell generation, and trans
https://www.stemcellcenter.lu.se/research-groups/woods - 2026-08-11
