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Human Tissue Lab

The human tissue laboratory (HTL) is a collaboration between EXODIAB and the Nordic Network for Clinical Islet Transplantation. The main tissue handled so far is human pancreatic islets. The islets are isolated at the islet isolation facility in Uppsala, primarily for transplantation purposes. A fraction of the islets that can not be used for transplantation, are upon agreed consent instead dedica

https://www.ludc.lu.se/human-tissue-lab - 2026-05-07

Winners of the Leif C. Groop Award for Outstanding Diabetes Research

The Leif C. Groop Award for Outstanding Diabetes Research is awarded annually by Lund University Diabetes Centre (LUDC) to a young investigator in the field of diabetes research who is active in any of the Nordic countries. The Leif C. Groop award was formerly known as the DPLU/LUDC Nordic Prize for an Outstanding Young Diabetes Investigator. In 2016, the award was renamed as a tribute to Professo

https://www.ludc.lu.se/ludc-ecn/leif-c-groop-award-winners - 2026-05-07

LUDC Early Career Network

It is especially important to meet and network with other researchers at the early stages of your career as a PhD student and diabetes scientist. The early career network at Lund University Diabetes Centre gives you the opportunity to do this and much more. The LUDC Early Career Network (LUDC ECN) organises events, awards grants, and works as a central hub for young scientists and students.  About

https://www.ludc.lu.se/ludc-ecn - 2026-05-07

Human Tissue Laboratory

The Human Tissue Laboratory (HTL) is an important resource for diabetes research established as a part of the strategic research area Excellence of Diabetes Research in Sweden (EXODIAB). This resource is accessible for researchers at the strategic research area and their collaborators based on approval. The Human Tissue Laboratory (HTL) was established in 2007 through a collaboration between Lund

https://www.ludc.lu.se/resources/human-tissue-laboratory - 2026-05-07

Cardiovascular Research – Hypertension

Olle Melander’s group Our researchWhen type 2 diabetes has been determined, a patient’s absolute risk of future cardiovascular disease events remains very high despite available preventive therapies. Thus, primary prevention of diabetes appears instrumental in reducing the population burden of diabetes-related cardiovascular disease. This group focuses on identifying mechanisms causally related to

https://www.ludc.lu.se/research/cardiovascular-research-hypertension - 2026-05-07

Medical Protein Chemistry

Anna Blom’s group Our researchOur group focuses on the complement system, which is part of the immune system. The complement system contains more than 40 proteins that circulate in the blood and these proteins play an important role in the innate defense against pathogens, and in the removal of unwanted materials.Researchers have discovered that complement proteins also have other functions; one e

https://www.ludc.lu.se/research/medical-protein-chemistry - 2026-05-07

Cardiovascular Research – Translational Studies

Isabel Gonçalves' group Our researchMany victims of heart attacks and stroke die before reaching the hospital. The most frequent cause of myocardial infarction and stroke is the rupture of an atherosclerotic plaque with the subsequent formation of a thrombus that occludes the vessel. The rupture-prone plaques are called vulnerable plaques (VP), and usually have a large lipid and necrotic core, are

https://www.ludc.lu.se/research/cardiovascular-research-translational-studies - 2026-05-07

Diabetes and Brain Function

João Duarte’s group  Our researchThe overall purpose of our research is to understand the molecular determinants underlying cognitive impairment associated with diabetes and metabolic syndrome components, including obesity, dyslipidaemia, hypertension, insulin resistance and hyperglycaemia.Our team is interested in understanding metabolic interactions between glial cells and neurons, how these are

https://www.ludc.lu.se/research/diabetes-and-brain-function - 2026-05-07

The LUDC Early Career Network

The LUDC Early Career Network (LUDC ECN) is an academic network at Lund University Diabetes Centre (LUDC). The network organises events, awards grants, and works as a central hub for young scientists and students at LUDC. The academic network works as a central hub for young scientist, postdoctoral fellows and students at LUDC. The academic network (formerly called DPLU) was formed in 2002 and, si

https://www.ludc.lu.se/ludc-ecn/about - 2026-05-07

Endocrine Cell Differentiation and Function

Isabella Artner’s group Our researchDiabetes results from loss or dysfunction of insulin producing beta cells in the pancreas. Despite insulin injection treatment, diabetic patients suffer from long-term complications, such as blindness and kidney failure. Therefore, a central goal of diabetes research is to regenerate pancreatic beta cells or produce large numbers of functional beta cells for tra

https://www.ludc.lu.se/research/endocrine-cell-differentiation-and-function - 2026-05-07

Insulin Signal Transduction

Eva Degerman’s group Our researchThere is a confirmed relationship between diabetes and dysfunction of the inner ear, our hearing and balance organ, and a large number of reviews and meta-analyses have been published on the subject. However, the mechanisms behind this association are not known. Our ongoing studies indicate that the inner ear is a direct target for insulin action and insulin resist

https://www.ludc.lu.se/research/insulin-signal-transduction - 2026-05-07

Pediatric Endocrinology

Helena Elding Larsson’s group Our researchThe overall purpose of our research is to investigate etiology, prediction, and prevention of pediatric autoimmune diabetes (type 1 diabetes) and other autoimmune diseases. Type 1 diabetes is preceded by an immune-mediated destruction of the pancreatic islet beta cells resulting in loss of insulin production. Genetic factors confer susceptibility and help

https://www.ludc.lu.se/research/pediatric-endocrinology - 2026-05-07

Innovation projects

Here we announce projects with innovation potential. Please contact Innovation Office at LUDC for more information. NCE targeting GPCR 321Anna Andersson and her group at Lund University Diabetes center  have identified a lead compound targeting GPCR 123. The new NCE induces insulin secretion and prevents beta cell apoptosis in vitro. The effects have been confirmed in vivo in a rat model, where ta

https://www.ludc.lu.se/innovation-projects - 2026-05-07

Diabetes – Islet Cell Exocytosis

Lena Eliasson’s group Our researchOur research aims to understand the impact of deregulated insulin- and glucagon-secretion from pancreatic islet of Langerhans in the aetiology of type 2 diabetes. We also have an interest in islet cell function in more rare diabetes types, such as cystic fibrosis-related diabetes (CFRD) and glucocorticoid-induced diabetes.The main focus of our research is to inves

https://www.ludc.lu.se/research/diabetes-islet-cell-exocytosis - 2026-05-07

Our research

LUDC is a consortium of research groups at Lund University headed by Leif Groop dedicated to unravelling the pathogenesis and treatment of diabetes mellitus. LUDC started July 1st 2006 when selected for funding by the Swedish Research Council (Vetenskapsrådet) in fierce national competition, as a part of the call for applications for Linneaus grants.  What does LUDC do?We are active in several dif

https://www.ludc.lu.se/our-research - 2026-05-07