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On 03 March 2023, Jenny Mattsson defended her Ph.D. thesis. With the goal to broaden the availability of antibody-based drugs for patients with cancer and other diseases, she has spent the past several years working to develop new methods that can be used to identify new antibodies and antibody targets. In this interview, we learn more about her research, how she has simultaneously juggled doing a

https://www.stemcellcenter.lu.se/article/new-methods-phenotypic-antibody-discovery-phd-interview-jenny-mattsson - 2025-12-11

Have you ever wondered what it takes to grow a brain in a petri dish or how scientists use viruses to fight genetic diseases? These are just some of the fascinating topics explored on UniStem Day 2023 at Lund Stem Cell Center in Sweden. On 10 March 2023, more than 220 high school students from across Sweden's southern Skåne region arrived at Lund Stem Cell Center at Lund University for a day of le

https://www.stemcellcenter.lu.se/article/inspiring-tomorrows-scientists - 2025-12-11

There is a large carton of chicken eggs on the bench in Sofie Mohlin's laboratory. They have been delivered during the morning and soon they will be placed in the 37-degree heat of the incubator so that the embryo can develop. Already 42 hours after fertilization, researchers can begin their experiments to study how neuroblastoma develops. Sofie Mohlin is an Associate Professor in Molecular Physio

https://www.stemcellcenter.lu.se/article/eggs-can-help-us-understand-neuroblastoma - 2025-12-11

Researchers at Lund Stem Cell Center and Lund University's Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major ne

https://www.stemcellcenter.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-12-11

For two decades, researchers at Lund University's strategic research area, Lund Stem Cell Center, have focused on developing and refining stem cell research to improve human health. Now that the 20th anniversary is approaching, it is time to reflect on the progress made and the possibilities that researchers see for stem cell research in the future. Stem cells can make any inventor green with envy

https://www.stemcellcenter.lu.se/article/vision-reality-20-years-cutting-edge-research-lund-stem-cell-center - 2025-12-11

Researchers from Lund Stem Cell Center are coming together with colleagues across Lund University to shape the future of healthcare. A new University-wide seed funding initiative seeking to support emerging research topics that benefit society will see interdisciplinary teams of neuroscience, medicine, and biotechnology researchers attempt to develop new, innovative, patient-specific disease model

https://www.stemcellcenter.lu.se/article/interdisciplinary-teams-lund-university-unite-develop-patient-tailored-disease-models - 2025-12-11

A recent study conducted by researchers at Lund University's Lund Stem Cell Center, and published in the Journal of Biological Chemistry, has unraveled the intricate inner workings of UM171—a molecule known for its ability to support blood stem cells. These findings not only highlight UM171's potential as a therapeutic solution for various diseases, including cancer, but also provide new insights

https://www.stemcellcenter.lu.se/article/decoding-inner-workings-blood-stem-cell-boosting-molecule - 2025-12-11

Lund Stem Cell Center researchers have published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the journal Brain Communications, provide valuable insights into the cellular mechanisms of the disease and open up new possibilities for developing early diagnostics and potential interventions for patients with FTD and other

https://www.stemcellcenter.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-12-11

Fredrik Nilsson successfully defended his Ph.D. thesis on May 10, 2023. For the last four years, Fredrik has explored the use of patient-specific cells in cell replacement therapy for Parkinson's disease to identify strategies to safeguard these transplanted cells from disease-related degeneration. In this interview, he tells us about his findings, their potential implications for future therapies

https://www.stemcellcenter.lu.se/article/investigating-cell-replacement-therapy-parkinsons-disease-phd-interview-fredrik-nilsson - 2025-12-11

Lund Stem Cell Center recently hosted its Image Competition for 2023, providing a glimpse into the diverse world of stem cell science through the lens of art. The competition showcased the dedication, creativity, and scientific excellence that continue to drive our pursuit of knowledge in stem cell research. Researchers from all disciplines and experience levels at Lund Stem Cell Center participat

https://www.stemcellcenter.lu.se/article/stem-cell-science-through-lens-art - 2025-12-11

New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for X-Linked Dystonia-Parkinsonism (XDP), Vivien aims to improve our understanding of XDP, a rare neurodegenerative disorder caused by the recent insertion of a transposable element. Transposable elements, also known as '

https://www.stemcellcenter.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-12-11

Mohamed Eldeeb defended his Ph.D. thesis on June 9, 2023. With a passion for scientific discovery with clinical impact, Mohamed has dedicated the last four years to unraveling the mysteries as to why some children develop pediatric leukemia and others don’t. His research shed light on the mechanisms that prevent and suppress leukemia initiation, paving the way for more effective and targeted treat

https://www.stemcellcenter.lu.se/article/mechanisms-initiation-and-suppression-pediatric-leukemia-phd-interview-mohamed-eldeeb - 2025-12-11

Lund Stem Cell Center welcomes the Targeted Therapies in Leukemia Research Group, led by molecular biologist Marcus Järås, as its newest member. With a strong background in translational research and a focus on developing innovative therapies, the group brings extensive expertise and a unique perspective to our stem cell science community at Lund University. Marcus Järås, a former student of the L

https://www.stemcellcenter.lu.se/article/targeted-therapies-leukemia-research-group-joins-lund-stem-cell-center - 2025-12-11

Lund University is establishing a university-wide development center for advanced therapies, LU-ATMP. It is an effort to move medical research with the potential for new groundbreaking therapies to reach patient groups where traditional medicines are not enough. "We want to contribute to the vision of Sweden becoming a world leader in the development and availability of advanced therapies," says E

https://www.stemcellcenter.lu.se/article/new-atmp-center-lund-university - 2025-12-11

Patricia Gerdes, a postdoctoral researcher specializing in transposable elements and their impact on the human genome, has been awarded a postdoctoral fellowship from the Marie Skłodowska-Curie Actions (MSCA) program. The grant will support a research project which focuses on understanding the role of transposable elements in human brain evolution, shedding light on healthy and disordered brain fu

https://www.stemcellcenter.lu.se/article/cracking-code-human-brain-evolution-patricia-gerdes-awarded-msca-fellowship - 2025-12-11

As certain tumor cells are able to conceal themselves in the body, it often means that patients with aggressive cancers experience a recurrence of the cancer after treatment. By programming genetically modified killer immune cells to seek and destroy the hiding tumor cells and tumor stem cells, it is hoped that we can develop more effective treatment options. An international research project, wit

https://www.stemcellcenter.lu.se/article/eu-funding-killer-cells-fight-cancer - 2025-12-11

Anna Falk, professor at Lund University's Stem Cell Center, will be the director of the newly established Center for Advanced Therapies, LU-ATMP. "My vision is that we will accelerate the development of all the advanced therapies underway at Lund University. Together with the healthcare and life science industry, we have the potential to make a significant contribution to new breakthrough treatmen

https://www.stemcellcenter.lu.se/article/stem-cell-researcher-anna-falk-heads-lund-universitys-center-advanced-therapies - 2025-12-11

Att barn till typ 2 diabetiker har en ökad risk att själva insjukna är väl känt. Nu visar ett internationellt forskarlag att de långt innan de insjuknar har såväl försämrad förmåga att utsöndra insulin som nedsatt känslighet för insulinet. Typ 2 diabetes orsakas av insulinbirst som kan bero på två olika faktorer. Dels en otillräcklig förmåga hos de insulinproducerande betacellerna att utsöndra til

https://www.diabetesportalen.lu.se/artikel/barnen-arver-daliga-insulinceller - 2025-12-11

Åtta av tio unga har kvar egen insulinproduktion ett år efter diagnosen typ 1 diabetes. En av tio till och med efter mer än fem år med sjukdomen. Detta är viktigt, blodsockret är lättare att kontrollera och risken för komplikationer senare i livet är lägre. Fyndet att så många så länge har kvar överlevande insulinproducerande betaceller går emot den gamla uppfattningen att den autoimmuna process s

https://www.diabetesportalen.lu.se/artikel/vanligt-med-overlevande-betaceller-hos-unga - 2025-12-11

Vid nyupptäckt typ 2 diabetes bör behandlingen med blodsockersänkande läkemedel starta tidigare än den ofta gör idag. För dem som haft sjukdomen ett antal år är strikt sockerkontroll inte lika självklar. Det är två av de slutsatser SBU gör i en ny rapport. Den nya rapporten, tillsammans med tre andra från SBU (Statens beredning för medicinsk utvärdering) fungerar som vetenskapligt underlag för Soc

https://www.diabetesportalen.lu.se/artikel/bra-med-tidig-tuff-behandling-vid-typ-2-diabetes - 2025-12-11