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A genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects

A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford universities in the UK and the Vanderbilt Genetics Institute in the US, the team recently published their findings in the journal Nature Metabolism.

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2026-06-15

Swedish research about different forms of type 2 diabetes is relevant for Indian people

Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes. A research collaboration between Sweden and India now highlights similarities and differences between patient groups in India and Europe. The knowledge can be used to improve

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2026-06-15

Epigenetics and genetics help illustrate how diabetes care can be individualised

Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? Some of the research at Lund University Diabetes Centre (LUDC) focuses on the progression of type 2 diabetes to help develop more targeted treatments. Epigenetics can become a useful tool when diabetes care is tailored to the individual. People with typ

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2026-06-15

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2026-06-15

Type 2 diabetes researchers receive support from the Hjelt Diabetes Foundation

Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes researchers at Lund University Diabetes Centre (LUDC) each a project grant of 47,500 euro. One of the researchers awarded a grant this year studies atherosclerotic plaques in patients with type 2 diabetes. These patients are more likely to develop cardiovascular disease due to plaque rupture compared to people without t

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2026-06-15

Gut and mouth bacteria give researchers new clues about atherosclerosis

What is the link between atherosclerosis and gut and mouth bacteria? Researchers behind a large new study have found several new connections. In the long term, this knowledge can benefit people with type 2 diabetes, a group with an increased risk of developing atherosclerosis. In atherosclerosis, fat and calcium have accumulated in the artery walls over time, forming so called atherosclerotic plaq

https://www.ludc.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2026-06-15

Positive metabolic effects of gastric bypass disappear quickly

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.  Previous research has shown that the majority

https://www.ludc.lu.se/article/positive-metabolic-effects-gastric-bypass-disappear-quickly - 2026-06-15

Skiers had lower incidence of depression and vascular dementia – but not Alzheimer’s

This article is over 5 years old, and the information may therefore be outdated. Half as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 w

https://www.multipark.lu.se/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimers - 2026-06-15

High-tech method for uniquely targeted gene therapy developed

This article is over 5 years old, and the information may therefore be outdated. Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of ye

https://www.multipark.lu.se/article/high-tech-method-uniquely-targeted-gene-therapy-developed - 2026-06-15

Blood test enables early diagnosis of Alzheimer's disease

This article is over 5 years old, and the information may therefore be outdated. Diagnosing Alzheimer's disease is often difficult, as several other conditions can cause similar symptoms. Researchers at Lund University in Sweden have now discovered a blood marker that can accurately diagnose Alzheimer’s in the early stages of the disease.Read the full article here

https://www.multipark.lu.se/article/blood-test-enables-early-diagnosis-alzheimers-disease - 2026-06-15

New imaging method sheds light on Alzheimer's disease

This article is over 5 years old, and the information may therefore be outdated. To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal A

https://www.multipark.lu.se/article/new-imaging-method-sheds-light-alzheimers-disease - 2026-06-15

New method provides unique insight into the development of the human brain

This article is over 5 years old, and the information may therefore be outdated. Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be

https://www.multipark.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2026-06-15

How toxic protein spreads in Alzheimer’s disease

This article is over 5 years old, and the information may therefore be outdated. Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilita

https://www.multipark.lu.se/article/how-toxic-protein-spreads-alzheimers-disease - 2026-06-15

Message from the coordinator

This article is over 5 years old, and the information may therefore be outdated. From the coordinator:As we approach Midsommar, we in MultiPark can reflect on the extraordinary last few months and hope that our environment can return back more to meetings, seminars and productive exchanges after the summer. Although neurodegenerative diseases were less in the news because of Covid-19, people with

https://www.multipark.lu.se/article/message-coordinator - 2026-06-15

New research paves way for developing therapies that could slow down Alzheimer´s

This article is over 5 years old, and the information may therefore be outdated. Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer’s disease pathology. The study has been published in Stem Cell Reports.Read the full article here.See also interview wit

https://www.multipark.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2026-06-15

New blood test shows great promise in the diagnosis of Alzheimer’s disease

This article is over 5 years old, and the information may therefore be outdated. A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer’s disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the J

https://www.multipark.lu.se/article/new-blood-test-shows-great-promise-diagnosis-alzheimers-disease - 2026-06-15

Millions from Michael J. Fox Foundation to improve diagnosis of Parkinson's

This article is over 5 years old, and the information may therefore be outdated. Around 20,000 people have been diagnosed with Parkinson's disease in Sweden. Today, there is no imaging method of changes in the brain that are believed to cause the disease. Researchers at Skåne University Hospital and Lund University have received nearly SEK 7 million from the Michael J Fox Foundation to develop an

https://www.multipark.lu.se/article/millions-michael-j-fox-foundation-improve-diagnosis-parkinsons - 2026-06-15

Of Four Aβ Antibodies, Only Aducanumab Stems Tide of Toxic Oligomers

This article is over 5 years old, and the information may therefore be outdated. Aducanumab was compared, in a blinded study, to three clinical-stage antibodies using chemical kinetics. The publication describes the use of chemical kinetic analysis to assess the mechanisms of action of four clinical stage anti-Aβ antibodies: aducanumab (Biogen), gantenerumab (Roche), bapineuzumab (Elan) and solane

https://www.multipark.lu.se/article/four-ab-antibodies-only-aducanumab-stems-tide-toxic-oligomers - 2026-06-15

App predicts risk of developing Alzheimer’s

This article is over 5 years old, and the information may therefore be outdated. A new study from Lund University in Sweden shows that validated biomarkers can reveal an individual’s risk of developing Alzheimer’s disease. Using a model that combines the levels of two specific proteins in the blood of those with mild memory impairment, the researchers are able to predict the risk of developing Alz

https://www.multipark.lu.se/article/app-predicts-risk-developing-alzheimers - 2026-06-15