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Lund University researchers find that individual blood stem cells (depicted as snowflakes in this image) express stress-related transcripts when subjected to experimental procedures involving cell incubation at elevated temperatures. Image // Marcin Minor Changes occur in all cells of the human body as we age. Blood stem cells, in particular, lose some of their functionality over time, contributin
In a study led by Lund University, researchers can show for the first time that traumatic brain injuries activate dormant endogenous retroviruses that have been inserted into human DNA over the course of millions of years. The activation of these viruses may be the driving force behind the inflammation that worsens the brain injury. The study is published in Cell Reports. In the event of head trau
https://www.stemcellcenter.lu.se/article/severe-brain-trauma-activates-dormant-endogenous-retroviruses-brain - 2025-08-29
‘The Bridge - Lungs for Life’ initiative received EU funding to establish a centralized Danish-Swedish "renovation facility" for damaged lungs – a first-of-its-kind endeavor in Europe. Photo credit: Karl Hörnfeldt // Unsplash Many lung patients face a critical shortage of organs for transplantation. To address this challenge, the ‘The Bridge - Lungs for Life’ initiative led by Professor Sandra Lin
https://www.stemcellcenter.lu.se/article/bridge-lungs-life-eu-funding-supports-oresund-lung-transplant-initiative - 2025-08-29
High school students from Skåne, Sweden, learn how to use chicken embryos to study childhood cancer with researchers in the Mohlin lab during UniStem Day 2024. In the heart of Lund, anticipation filled the air as over 230 high school students from across Skåne, Sweden, gathered in a bustling auditorium at Lund University on Friday, March 22nd. UniStem Day 2024, an annual event hosted by the Lund S
Desiree Dickerson leads the workshop "Connecting Minds: Navigating Isolation and Building Belonging in Academic Life" with a diverse group of researchers, students, and staff from the Lund Stem Cell Center. Isolation is a major problem for many in Academia. To counteract this among researchers and doctoral students alike, the working group for diversity, equality and inclusion (DEI) within the Lun
https://www.stemcellcenter.lu.se/article/wellbeing-and-belonging-promote-success-academia - 2025-08-29
Researchers studying natural killer cells present a comprehensive map of how these cells develop in humans, detailing their regulatory networks along the way. Image credit: AI-illustrated artwork via Midjourney // Dang Nghiem Vo At any given time, more than 2 billion natural killer cells patrol the adult bloodstream as frontline defenders, protecting against infections and cancer. In a recent stud
https://www.stemcellcenter.lu.se/article/drawing-molecular-roadmap-human-natural-killer-cell-development - 2025-08-29
Photo from stem cell transplantation at Skåne University Hospital. Source: Skåne University Hospital. Higher dose cohort initiated after positive early safety evaluation in Parkinson's therapy. After a positive initial safety evaluation, the pioneering STEM-PD clinical trial has advanced to higher dose testing. STEM-PD is a first-in-human clinical trial testing a new investigational therapy for Pa
https://www.stemcellcenter.lu.se/article/update-stem-pd-clinical-trial-stem-cell-based-transplant-parkinsons-disease - 2025-08-29
Researchers at Lund University and the Technical University of Denmark (DTU) in Copenhagen have discovered a new method that takes us one step closer to universal blood. Image: iStock/MusMuculus. Researchers at Lund University and DTU in Copenhagen have discovered enzymes in the colon that, when mixed with red blood cells, can cut away parts of the carbohydrates that separate our ABO blood groups
https://www.stemcellcenter.lu.se/article/enzymes-intestinal-bacteria-opens-universal-blood - 2025-08-29
Anna Fossum, head of the FACS Core Facility research infrastructure, along with researchers Nicholas Leigh, Chimezie Umeano, and Marlene Johanna Oesterle, collect and analyze data on the new BD FACSDiscover. Photo: Alexis Luis. At Lund University’s Biomedical Centre, the FACS Core Facility hums with activity, hosting a range of machines ready to support scientific research. Now, the facility welco
https://www.stemcellcenter.lu.se/article/new-era-flow-cytometry-arrives-facs-core-facility - 2025-08-29
Researchers at Lund University have discovered how a hidden piece of DNA, known as a transposable element, disrupts normal gene function in a disease called X-Linked Dystonia-Parkinsonism (XDP). Image // Science Photo Library Researchers at Lund University have discovered how a hidden piece of DNA, known as a transposable element, disrupts normal gene function in a disease called X-Linked Dystonia
https://www.stemcellcenter.lu.se/article/how-hidden-genetic-elements-trigger-rare-disorder - 2025-08-29
The Lund Stem Cell Center held its annual image competition from April to May 2024. In June, the 15 image entries were assessed, and the top images were selected according to the evaluators' scores. There comes a point in every researcher's work when the data goes beyond numbers and charts, transforming into something visually captivating. The annual Image Competition held by the Lund Stem Cell Ce
https://www.stemcellcenter.lu.se/article/where-science-meets-art-inside-lund-stem-cell-centers-2024-image-competition - 2025-08-29
By reprogramming tumour cells to become the body’s defenders, Filipe Pereira and his colleagues hope to improve current cancer treatments. Photo by: Johan Persson Filipe Pereira and his research team have discovered a recipe on how to reprogram cancer cells into antigen-presenting dendritic cells, essential for initiating and enhancing anti-tumour immunity. This approach provides a promising strat
https://www.stemcellcenter.lu.se/article/professor-filipe-pereira-awarded-erc-proof-concept-grant - 2025-08-29
Sofie Mohlin's research team has discovered that the MOXD1 gene is associated with neuroblastoma. Every year, about twenty children in Sweden get neuroblastoma. Most of them are diagnosed before the age of five. Some develop the disease in the fetal stage Neuroblastoma is a tumor disease that primarily affects young children. The survival rate is the lowest of all childhood cancers. Now, a researc
https://www.stemcellcenter.lu.se/article/gene-controls-prognosis-neuroblastoma - 2025-08-29
In May 2024, Dr. Olle Lindvall was awarded a jubilee doctorate from Lund University in recognition of his 50-year anniversary of first earning his doctoral degree. Photo by: Mattias Lindvall. Dr. Olle Lindvall, recently awarded a jubilee doctorate from Lund University, has spent more than fifty years studying the brain and how to repair it. His work has turned ideas that once seemed like science f
Researchers are developing a new cancer immunotherapy that reprograms cancer cells into dendritic cells using an adenoviral vector. The image shows how this new approach, tested In preclinical studies, works. Image credit: Joana Carvalho. Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune sy
https://www.stemcellcenter.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-08-29
PhD student Luís Oliveira drew resounding applause for his presentation on how he reprograms cancer cells. Photo: Bodil Malmström. By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for r
Olga Zimmermannova from the Pereira Research Group has been awarded the 2024 Article of the Year Award. She received the award for her research on reprogramming cancer cells into dendritic cells of the immune system as a potential cancer therapy. The Lund Stem Cell Center Article of the Year Award, presented annually since 2017, highlights exceptional research conducted at the Center that contribu
https://www.stemcellcenter.lu.se/article/lund-stem-cell-centers-2024-article-year-goes-olga-zimmermannova - 2025-08-29
Two researchers at Lund Stem Cell Center receive grants, 61 million, for research into immunological long-term memory and reprogramming of tumor cells. The research should lead to more effective vaccination strategies and immunotherapies. The Knut and Alice Wallenberg Foundation has granted SEK 835 million to 30 different projects in medicine, natural science and technology that are deemed to have
https://www.stemcellcenter.lu.se/article/yuan-and-pereira-receive-grants-wallenberg-foundation - 2025-08-29
Joan Yuan is honored "For her seminal discoveries that have changed our understanding of hematopoiesis and the immune system". Photo: Åsa Hansdotter Joan Yuan, researcher and associate professor in immunology, receives the Eric K. Fernström prize for younger, particularly promising and successful researchers at Lund University in 2024. Her research is about how the immune system is formed and how
https://www.stemcellcenter.lu.se/article/eric-k-fernstrom-award-young-successful-researchers-goes-joan-yuan - 2025-08-29
The study was a joint effort between doctoral student and first author Ninoslav Pandiloski (centre), postdoctoral researcher Vivien Horvath from the Laboratory of Molecular Neurogenetics (left), and PI Christopher Douse (right). Photo by: Alexis Luis. Researchers at Lund University’s Lund Stem Cell Center have made a new discovery about how the human genome protects itself from disruption during c
https://www.stemcellcenter.lu.se/article/new-research-gives-insights-human-genomes-defence-mechanisms - 2025-08-29
