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New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Previous research by diabetes researcher Rashmi Prasad has shown

https://www.ludc.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-11-11

The results of an observational study from Lund University in Sweden are clear: up to the age of two, a more fibre-rich diet seems to reduce the risk of coeliac disease. A particularly clear link was seen when children had eaten fibre-rich foods before the age of one. “This is the first time the risk of coeliac disease has been studied based on fibre in children’s diets. But a clinical trial is al

https://www.ludc.lu.se/article/new-research-track-higher-amounts-dietary-fibre-age-two-can-reduce-later-risk-coeliac-disease - 2025-11-11

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh

https://www.ludc.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-11-11

International researchers who study islets of Langerhans met for a conference in Malmö in June. Studies of insulin-producing cells help us understand disease mechanisms in diabetes. Lund University Diabetes Centre and the strategic research area EXODIAB hosted the event. Lund University Diabetes Centre (LUDC) and the strategic research are EXODIAB (Excellence of Diabetes Research in Sweden) hosted

https://www.ludc.lu.se/article/international-islet-cell-researchers-met-conference-malmo - 2025-11-11

Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in precision medicine, focusing on epigenetic analysis of blood samples from 13,000 individuals. Charlotte Ling, a professor in diabetes research with a particular focus on epigeneti

https://www.ludc.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-11-11

An international research team led from Lund University, has identified epigenetic biomarkers that can predict which people with type 2 diabetes are at risk of cardiovascular disease. The study is now published in Cell Reports Medicine. People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people. Therefo

https://www.ludc.lu.se/article/biomarkers-reveal-risk-cardiovascular-disease-type-2-diabetes - 2025-11-11

Inflammation researcher Ben King studies the function of two different proteins in connection with diabetes. In the future, such knowledge may be important for the development of new treatments for people with diabetes. Ben King is this year’s recipient of the Medeon Award for his innovative research. “I was very surprised and feel very honored to receive the award. In my role, I do a lot of exper

https://www.ludc.lu.se/article/award-protein-research-may-lead-new-treatments-diabetes - 2025-11-11

We would like to congratulate six researchers at Lund University Diabetes Centre, who have been awarded research grants within medicine and health by the Swedish Research Council (VR). The six researchers are affiliated with Excellence of Diabetes Research in Sweden (EXODIAB), which is a strategic research area within diabetes at Lund University.Helena Elding Larsson, professor of autoimmune disea

https://www.ludc.lu.se/article/six-ludc-researchers-receive-medicine-and-health-grants-vr - 2025-11-11

Social and economic factors have led to a dramatic rise in type 2 diabetes and obesity around the world. In a review in Science, Mark McCarthy, professor at the University of Oxford, UK, and Paul Franks, professor at Lund University, Sweden, examine the knowledge of the actual causes and the interplay between genetics and lifestyle factors. By studying how our genes express themselves in response

https://www.ludc.lu.se/article/review-type-2-diabetes-and-obesity-what-do-we-really-know - 2025-11-11

Lund University Diabetes Centre has entered into a collaboration with the Regeneron Genetics Center LLC (RGC) and the University of Helsinki involving exome-sequencing and whole genome array genotyping of greater than 9,000 individuals. The collaboration will involve the largest sequencing study in diabetes families to date and aims to help generate knowledge about how to predict diabetes, causes

https://www.ludc.lu.se/article/lund-initiates-genetic-sequencing-study-diabetes-families-provide-new-insights-what-causes-disease - 2025-11-11

Research from Lund University in Sweden can explain why type 2 diabetes is inherited to a greater extent from an individual’s mother. The heredity of a previously known risk gene, THADA, has proven to be dominant if it comes from the mother, whereas it has little or no effect on the child’s risk of disease if it originates from the father.
“Our research contributes to increased knowledge about the

https://www.ludc.lu.se/article/thada-new-findings-role-mother-type-2-diabetes - 2025-11-11

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

“This could explain why the risk of type 2 diabetes is greater among, for instance, overnight workers or people with sleeping disorders”, says Professor Hindrik Mulder who is responsible for the study. Melatonin is a naturally

https://www.ludc.lu.se/article/new-findings-explain-connection-between-melatonin-and-type-2-diabetes - 2025-11-11

One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous analyses have not been able to identify genetic causes as to why some people have a h

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage - 2025-11-11

One in three people with diabetes will face some form of renal impairment in the course of their lives. Studies conducted by researchers at the Lund University Diabetes Centre may lead to the development of an entirely new principle for treating type 2 diabetes and preventing kidney damage in the future. Previous analyses have not been able to identify genetic causes as to why some people have a h

https://www.ludc.lu.se/article/new-findings-can-lead-new-principle-treating-diabetic-kidney-damage-0 - 2025-11-11

The European Research Council makes a large investment in diabetes research. A project led by Professor Paul Franks at Lund University Diabetes Centre is to develop methods that can be used in the design of preventive treatment for type 2 diabetes and cardiovascular disease. - Through this project we will use functional genomics and epidemiology to identify novel molecular mechanisms that underlie

https://www.ludc.lu.se/article/focus-personalized-treatment-type-2-diabetes-and-cardiovascular-disease - 2025-11-11

Social and economic factors have led to a dramatic rise in type 2 diabetes and obesity around the world. In a review in Science, Mark McCarthy, professor at the University of Oxford, UK, and Paul Franks, professor at Lund University, Sweden, examine the knowledge of the actual causes and the interplay between genetics and lifestyle factors. By studying how our genes express themselves in response

https://www.ludc.lu.se/article/type-2-diabetes-and-obesity-what-do-we-really-know - 2025-11-11

Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden. In a new study, doctoral student Cajsa Davegårdh has studied so-called DNA methylation in muscle stem cells in both obese and non-obese individuals. DNA methylation is an epigen

https://www.ludc.lu.se/article/obesity-reprogrammes-muscle-stem-cells - 2025-11-11

New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Previous research by diabetes researcher Rashmi Prasad has sh

https://www.medicine.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-11-11

LONGREAD. He treats tremor with sound waves, is preparing to help paralyzed patients control a cursor with their thoughts and envisions a future where brain and machines talk to each other in both directions. Neurosurgeon and researcher Andres Lozano is pushing the boundaries of what is possible in the human brain – and doing it with both precision and imagination. “We are trying to discover the b

https://www.medicine.lu.se/article/fine-tuning-neural-circuits-heal-brain-segerfalk-lecturer-andres-lozano-next-gen-neurosurgery - 2025-11-11

A simpler method of analysing blood samples for Alzheimer’s disease has been tested in a large multicentre study, led by Lund University in Sweden. “This is a major step in bringing simple blood tests for Alzheimer’s disease into the healthcare system globally,” say the researchers behind the study. In brief:The blood-based marker (P-tau217) may start to change several years before the onset of Al

https://www.medicine.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-11-11