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Oxidative stress-related genetic variation and antioxidant vitamin intake in intact and ruptured abdominal aortic aneurysm : a Swedish population-based retrospective cohort study

AIMS: The aim of this study is to investigate how genetic variations in genes related to oxidative stress, intake of antioxidant vitamins, and any potential interactions between these factors affect the incidence of intact abdominal aortic aneurysm (AAA) and its rupture (rAAA), accounting for sex differences where possible.METHODS AND RESULTS: The present retrospective cohort study (n = 25 252) us

Klassriket Klasskunskaper i den svenska partipolitiska sfären, 1911-1940

This article investigates the creation and circulation of class knowledge among Sweden's political parties as Swedish representative democracy took shape, 1911-1940. When the expanded franchise for men was introduced in the general election of 1911, the National Statistics Bureau (SCB) was tasked with categorising voters to measure the effects of the reform. They created a taxonomy made up of thre

Class Divisions in Use : The Swedish Social Group Taxonomy as Difference Technology, 1911-1970

This article investigates an important but understudied phenomenon: the bureaucratic class division, which is analysed as a difference technology for envisioning, studying and managing the population. I examine a long-lived and widely spread taxonomy of the Swedish population into three social groups (Socialgrupper). Specifically, I look at how it influenced the production of statistics and knowle

Klass i begåvningsreservens tidevarv : Taxonomiska konflikter inom och genom svensk utbildningsforskning, ca 1945–1960

This article studies conceptualisations of social class in Swedish education research, c. 1945–1960. The article follows knowledge produced about talent and class in state commissions and in the newly expanded social sciences, and how it in turn was interpreted and used in political debates and in the media. I show that the taxonomy of the population in social groups (Socialgrupper) was key for co

Responsibility and Ambivalence

I use the concept of ambivalence—the state of being faced with a choice that cannot be resolved without sacrificing something of value—to approach five contemporary debates in the philosophy of moral responsibility: (1) psychopathy, (2) free will, (3) the emotion of guilt, (4) regret and indirect moral luck, and (5) moral demandingness. Rather than arguing for one theory or another, acknowledging

Quality Control in ECG-based Atrial Fibrillation Screening

This thesis comprises an introductory chapter and four papers related to quality control in ECG-based atrial fibrillation (AF) screening. Atrial fibrillation is a cardiac arrhythmia characterized by an irregular rhythm and constitutes a major risk factor for stroke. Anticoagulation therapy significantly reduces this risk, and therefore, AF screening is motivated. Atrial fibrillation screening is o

Gender (in)equality within the Swedish Armed Forces : Resistance and Functional Disinclination

Historically and traditionally, military work has been closely associated with men. However, the post-Cold War normalization process has brought about a transformation in both the Swedish Armed Forces themselves and the perception of the organization. Normative concerns, including gender equality, have gained significant prominence, compelling the armed forces to embark on various initiatives aime

CenTauR : Toward a universal scale and masks for standardizing tau imaging studies

INTRODUCTION: Recently, an increasing number of tau tracers have become available. There is a need to standardize quantitative tau measures across tracers, supporting a universal scale. We developed several cortical tau masks and applied them to generate a tau imaging universal scale. METHOD: One thousand forty-five participants underwent tau scans with either 18F-flortaucipir, 18F-MK6240, 18F-PI2

Genetic Moderation of the Association of β-Amyloid With Cognition and MRI Brain Structure in Alzheimer Disease

Background and Objectives: There is considerable heterogeneity in the association between increasing β-amyloid (Aβ) pathology and early cognitive dysfunction in preclinical Alzheimer disease (AD). At this stage, some individuals show no signs of cognitive dysfunction, while others show clear signs of decline. The factors explaining this heterogeneity are particularly important for understanding pr

Evaluation of single-fraction high dose FLASH radiotherapy in a cohort of canine oral cancer patients

Background: FLASH radiotherapy (RT) is a novel method for delivering ionizingradiation, which has been shown in preclinical studies to have a normal tissuesparing effect and to maintain anticancer efficacy as compared to conventionalRT. Treatment of head and neck tumors with conventional RT is commonlyassociated with severe toxicity, hence the normal tissue sparing effect of FLASHRT potentially ma

Rethinking bioeconomy innovation in sustainability transitions

Over the past two decades, a new research field dealing with “sustainability transitions” has emerged, analyzing the transformation of socio-technical systems towards more sustainable futures. While there is consensus on the crucial role of the bioeconomy in sustainability transitions research, we argue that the true potential of many bioeconomy innovations is not yet sufficiently recognized and a

Discrete episodes of elevated terrestrial runoff during the Carnian climate changes

The Carnian Pluvial Episode (CPE) was an interval of prominent hydroclimatic perturbations during the early Late Triassic. The causes of these changes have been widely attributed to intensified greenhouse forcing. However, the temporal dynamics of the hydrological cycle across low-latitude regions during the CPE remain poorly constrained. In this study, we present high-resolution organic geochemic

First measurement of Ds1(1+)(2536)+ and D*s2 (2+)(2573)+ production in proton-proton collisions at √S=13S2Te V at the LHC

The production yields of the orbitally excited charm-strange mesons (Formula presented) and (Formula presented) were measured for the first time in proton-proton (pp) collisions at a center-of-mass energy of (Formula presented) with the ALICE experiment at the LHC. The (Formula presented) and (Formula presented) mesons were measured at midrapidity ((Formula presented)) in minimum-bias and high-mul

Context matters: Understanding the platformization of violence

This introductory paper outlines the conceptual foundations and research agenda for our special issue Contextual Complexities of Violence on Digital Platforms. We argue that violence on digital platforms cannot be understood as a fixed or self-evident category, but must be situated within the sociotechnical, cultural and political environments that shape its production, circulation and recognition

Gender and reproductive rights : Synergies and contradictions in China’s national and global development agendas

This chapter draws on recent literature to outline the trajectory of China’s national development in the fields of gender equality and sexual and reproductive health and rights (SRHR), as well as its global engagement in these fields. By highlighting how Chinese national and global development agendas speak to and depart from each other, it attempts to identify potential synergies and contradictio

Ett vatten : Hållbar lokal systemomställning för global applikation

EHLSA har visat att en ökad kraftsamling kring källsorterat avlopp, etableringen av ett innovationsekosystem, och systemdemonstratorer tillsammans kan, om detgörs på rätt sätt, skapa en katalysator för omställningen från linjärt till cirkulärt VA. Dagens omställningssystem fungerar långt ifrån optimalt och syntesen föreslår fyra huvudsakliga utvecklingspunkter:• Gå från ett innovationsekosystem ti