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Avner de Shalit argues that philosophers should listen to what the public thinks. He argues that by engaging with people in the streets, political philosophy will improve. Yet, what makes the public special in this regard? This response will do three things. First, it asks whether discussing with the public differs in any meaningful way from discussing with other people such as colleagues or stude

As circular economy (CE) strategies become mainstream in policy and business practice, concerns have emerged about their narrow focus on techno-economic efficiency, often associated with “weak sustainability”. In parallel, a growing number of grassroots, public, and hybrid initiatives have emerged at the local level, bridging product and material recovery with social inclusion, education, and ecol

From the Wunderkammern of Renaissance Europe to the curated vaults of today’s natural history museums, millions of insect specimens have been preserved, capturing an irreplaceable chronicle of biodiversity, including lineages that are rare, highly specialized, or already extinct. Yet their fragility has historically constrained genomic inquiry. Here, we apply museomic methodology to a >40-year-old

Housing preferences in later life vary, and housing decisions are complex. While much attention has been paid to health and accessibility, less is known about how financial factors influence housing decisions among older homeowners. This qualitative study aimed to deepen understanding of how single-family homeowners aged 55 and older reason about their housing situation. We conducted focus groups

Småföretag med färre än 50 anställda är dominerande i både svenskt och många andra länders näringsliv. En delgrupp bland småföretag är mikroföretag med färre än 10 anställda. Syftet med denna rapport är att fördjupa förståelsen för hur arbetsmiljöarbetet upplevs och genom förs i småföretag, samt vilka hinder och möjligheter som kan förekomma i dessa företag i relation till arbetsmiljöarbetet. Rapp

Background: Early identification of patients with suspected infection who are at risk of clinical deterioration in the Emergency Department (ED) is challenging, yet crucial for timely initiation of appropriate care and prevention of clinical deterioration. This multicenter international study evaluates the performance of established scores (SIRS, LODS, qSOFA, SOFA, NEWS) in predicting severe outco

The viability of a main-group triple bond depends critically on the strength of its π-manifold. Among the 15 possible diatomic homo- and interpnictogens, EE′, (E, E′ = group 15 element), the NN linkage of dinitrogen stands out as one of the strongest triple bonds that exists, whereas the heavier pnictogens form thermodynamically unstable triple bond motifs that either decompose to single-bonded ol

Photon counting computed tomography (PCCT) provides exceptional image quality with reduced radiation dose in temporal bone imaging and is emerging as a potential new gold standard. This study aims to assess the feasibility of an in-house micro-computed tomography (micro-CT) system equipped with Photon Counting Detector (PCD) technology and to compare it with a clinical PCCT scanner for temporal bo

Using ultra-broadband transient terahertz (THz) spectroscopy, complemented by transient absorption (TA) and photoluminescence (PL) measurements, we directly track the generation and relaxation of photoexcited hot carriers, as well as the ultrafast formation of excitons in the transition metal phosphorus trichalcogenide NiPS3, with a temporal resolution of sub-100 fs. A subset of excitons exhibits

Accurate prediction of groundwater levels (GWL) is essential for effective and sustainable water resource management, particularly in arid and semiarid regions where excessive extraction and climate change significantly accelerate aquifer depletion. The nonstationary characteristics of groundwater data pose significant challenges to the performance and reliability of conventional machine learning

Three plant researchers describe in this book how plants emerged via the fusion of several different types of simple prokaryotic organisms and, through algae, evolved into land plants. During their evolution, they survived global ice ages, violent volcanic eruptions, and collisions with celestial bodies. The authors follow the development of landplants along various paths- some of which have ended

A 47-year-old woman with metastatic pancreatic adenocarcinoma, diagnosed five months earlier and treated with palliative chemotherapy, was admitted with fever, jaundice, and right upper quadrant pain consistent with ascending cholangitis. Treatment with antibiotics was initiated and an endoscopic retrograde cholangiography was performed, whereby a biliary stent was placed to relieve malignant bili

Objectives: SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss-of-function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes. Here we describe a novel dominant variant in SLC4A4 in patients wit

Background: T cell receptor (TCR) binding properties have been related to a wide range of pathological conditions, including infections, autoimmunity and cancer. Characterising the TCR repertoire is of great biomedical interest but it has been challenging due to its high structural diversity. Methods: In situ sequencing (ISS) is a suitable technique for spatial cell typing and linking gene pattern

Osteoarthritis (OA)-related meniscal degeneration involves complex interactions between oxidative stress and proteasomal dysfunction. However, the molecular drivers of regional meniscal vulnerability remain poorly defined. This study integrated multiple transcriptomic datasets from OA and control menisci to identify functional networks and hub genes by using weighted gene co-expression network ana

The proliferation of renewable energy resources is imposing demands on electric distribution infrastructure that traditional low-frequency transformers are not equipped to fulfill. Conventional transformers operate with high energy efficiency but offer zero active controllability with no inherent power quality management and support for hybrid power flows. The solid state transformer (SST), a powe