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Background: Mapping social and geographical disparities in health outcomes helps to identify vulnerable groups that should be targeted for intervention. This study aims to assess the disparities in cardiometabolic multimorbidity, the presence of at least two cardiometabolic diseases (CMD), including type 2 diabetes, heart disease, and stroke, among middle-aged adults across socio-geographical inte
Aerosols substantially influence the climate by modifying Earth’s radiative balance and marine biogeochemical cycles. However, accurate quantification of aerosol deposition onto ocean surfaces remains challenging due to the limited direct observations over oceanic regions. Here, to address this observational gap, we use the cosmogenic radionuclide beryllium-7, measured simultaneously in the atmosp
Intensity ratio-based phosphor thermometry is a promising technique for instantaneous temperature measurement of fast-moving objects. However, its accuracy is limited by the blueshift effects of interference filters induced by angle of incidence (AOI) variations. This is especially problematic for phosphors with significant temperature-dependent emission band shifts. To address this issue, we prop
Background: Occupational balance (OB) is a subjective feeling of having the right amount and variety of occupations. Aims/objectives: The study aims to translate the Occupational Balance Questionnaire (OBQ11) into Chinese (OBQ11-C) and to examine its psychometric properties for people with depression in Taiwan. Material/methods: The OBQ11 was translated and reviewed by 10 experts. Subjects with de
Objective: To estimate the 12-year risk of radiographic and/or symptomatic knee osteoarthritis following different MRI-confirmed soft-tissue knee injuries. Design: Prospective cohort study including 814 (70 %) of 1129 consecutive patients after acute knee trauma with hemarthrosis in a single hospital. Injuries were classified by sub-acute knee MRI. Follow-up comprised bilateral knee radiography a
Easy and low-threshold access is considered to be a major advantage of online services. In Sweden, social services in several municipalities strive to increase their accessibility by responding to anonymous users online. This paper raises the question about the nature of accessibility that the online social services entail. Two online platforms were studied: synchronous online chats and asynchrono
The Intermediate Wheatgrass (IWG) Thinopyrum intermedium (Host) Barkworth & D.R. Dewey, marketed under the trade name Kernza® has been tested in France with a group of farmers since 2017. The Life Cycle Assessment (LCA) is a recognized methodology to assess the potential environmental impacts and resources consumption associated with a production system. An attributional LCA following ISO 1404
Climate change pushes species toward higher latitudes and altitudes, but the proximate drivers of range expansions vary, and it is unclear whether evolution facilitates climate change–induced range changes. In a temporally replicated field experiment, we trans-located wall brown butterflies (Lasiommata megera) descending from range interior and range margin populations to sites at 1) the range int
This paper examines the practice of signposting in online counselling provided by the social services in Sweden. Specifically, it focuses on cases where online users are steered to seek offline help. The data corpus consists of 68 online chat logs (quasi-synchronous interactions) and 200 Internet question form exchanges (asynchronous interactions). The data were examined using the approach of conv
Background: Sjögren’s disease (SjD) is an autoimmune condition affecting exocrine glands, resulting in decreased saliva and tear production. Aquaporin 5 (AQP5) is a transmembrane water channel playing a central role in water transport. In SjD, deregulation of AQP5 expression, trafficking and interactions with various proteins contribute to the underlying disease mechanisms. Methods: Co-immunopreci
Some vertebrates regenerate appendages through the action of small noncoding RNAs (smRNAs) expressed in their blastema. Inspired by these models, we investigated whether similar smRNA-mediated mechanisms might contribute to the intrinsic repair capacity of human cartilage. Although humans lack the capacity to regenerate entire limbs, digit tip regrowth and joint cartilage repair following joint di
Introduction: Amyloid- and tau-positron emission tomography (PET) are promising modalities for detecting pathological changes associated with Alzheimer’s disease (AD); however, their application is limited. Although the use of cerebrospinal fluid (CSF) biomarkers as alternatives to amyloid-PET and tau-PET has been explored, no in vitro diagnostic-approved or commercial CSF biomarker assays are cur
How is Turkish official memory negotiated locally in Izmir, a city celebrated as a symbol of national becoming, yet (im)famous for its scepticism of central power? How is the past of the city narrated, conceived as an epitome of progress, yet built on a systematic forgetting of trauma and violence? And how does the secularist legacy of Izmir, accentuated in contrast with the Islamisation of memory
Objective: The aim was to resuscitate and evaluate hearts ex vivo after 22 min of cardiac arrest with the goal of increasing the number of usable hearts from controlled donation after circulatory death (cDCD). Design: Eight pigs (39–61 kg) underwent 22 min of ventricular fibrillation, after which the heart was first perfused in vivo for three minutes with an oxygenated, erythrocyte-containing card
In landscapes shaped by intense agriculture, even common bee species may face limits to their dispersal capacity. We explored how spatial isolation and land-use types influence the genetic population structure of two generalist mining bees – Andrena haemorrhoa and A. nigroaenea – which differ in body size and putative dispersal potential, yet share similar ecological niches. Using a network of iso
On October 29 2023, Turkey celebrates the centenary of the Republic. We may anticipate this to be an equally spectacular and politicized event: a purported celebration of national unity, which in essence will reproduce and re-affirm distinct political wedges. Carefully choreographed national celebration has a long history in Turkey. And historiography has been its narrative bedrock, highlighting t
Objective: To estimate the probability of vaginal events (diagnosis and/or surgery) following radical cystectomy (RC) and explore possible risk factors in a nationwide population-based observational registry based study. Patients and Methods: Women undergoing RC for urinary bladder cancer in Sweden, from 1 January 1997 to 31 December 2019, were identified within national registries. Women with any
Nocturia, the urge to wake from sleep to void, is targeted sub-optimally by existing drugs that modulate circadian dysregulation of urine production in kidney without alleviating detrusor overactivity, a key aspect in the multifactorial etiology of nocturia. This study reports age-related upregulation of arginine vasopressin (AVP) synthesis in mouse urinary bladder to counter the concurrent declin
On 29 October 2023, Turkey will celebrate the centenary of the proclamation of the Republic. This promises to be a spectacular and carefully politized event, in line with earlier celebrations of National Days and other “defining moments” in the state’s autobiography (such as the conquest of Istanbul – celebrated in ever-aggrandising scale under the AKP-government). In official historiography, the
