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Neuromuscular disorders (NMDs) are disorders of the motor unit (motor neuron diseases, diseases of the peripheral nerves, neuromuscular junction diseases, and diseases affecting the muscle fibers). A common denominator of these diseases is muscle atrophy and progressive weakness. Quantitative assessments of muscle function are therefore essential to follow disease progression, to understand the as
The Lepidoptera, butterflies and moths, display an astonishing diversity of spatial orientation strategies essential for survival, reproduction, and ecological success. These spatial orientation strategies range from basic taxes to light, wind, gravity, and chemical cues, to more advanced strategies such as straight-line dispersal, multigenerational migration across continents, and complex trap-li
Background Dietary diversity may affect type 2 diabetes (T2D) but no studies have examined protein diversity by source. We examined five diversity scores and the 10-year risk of T2D and effect modification. Methods A prospective study of 10 363 incident T2D cases and a representative sub-cohort of 13 937 individuals sampled from a cohort of 340 234 participants in eight European countries (1993-20
Background: Glioblastoma, IDH wildtype is the most common primary malignant brain tumor in adults. Despite best available treatment, prognosis remains poor. Current standard therapy consists of surgical tumor removal followed by radiotherapy and chemotherapy with the alkylating agent temozolomide. Antisecretory factor (AF), an endogenous protein, may potentiate the effect of temozolomide and allev
Seagrass meadows are vital habitats, modifying hydrodynamic energy flows and sustaining biodiversity in the benthic environment. As such, there is a growing interest in using seagrass as a nature-based solution for coastal adaptation. However, planting seagrass in hydrodynamically exposed environments is challenging, and the trajectories and timescales of biodiversity recovery are not well studied
RATIONALE: Caffeine is commonly used in preterm infants to improve respiratory function. However, the optimal strategies for caffeine initiation have not been defined. OBJECTIVES: To evaluate the relative benefits and harms of different indications and timings for caffeine initiation in preterm infants. SEARCH METHODS: We searched MEDLINE, Embase, CENTRAL, and trial registries up to 23 April 2025.
Cervical screening frequency has not been studied in vaccinees. As the major risk factor, oncogenic human papillomavirus (HPV) is declining due to vaccination. We report a trial to assess the effectiveness of cervical screening frequency among women HPV-vaccinated as early adolescents (NCT02149030). In 2013, 5626 1992-1995-born women, who had received three doses of the HPV16/18 vaccine at ages 12
Objective: To describe the clinical and ultrasound characteristics at the time of diagnosis of primary ovarian immature teratoma with no other germ cell tumor components described on histopathology. Methods: This was a retrospective study of women with a histological diagnosis of primary ovarian immature teratoma who had undergone a preoperative ultrasound examination between 1998 and 2024. Cases
This letter addresses loss of packets in a wireless fronthaul link being interpreted as channel errors for the service link. This may occur if, for instance, User Equipment (UE) is served by a radio unit in an Uncrewed Aerial Vehicle (UAV) via a wireless fronthaul link to a baseband unit (BU) on the ground. The fronthaul packet loss leads to a mismatch between the real and estimated channel state,
Introduction Lynch syndrome (LS) carriers have a 20-46% lifetime risk of colorectal cancer (CRC) due to mismatch repair gene variants. Mesalamine (5-ASA, 5-aminosalicylic acid), used safely in patients with ulcerative colitis, may reduce CRC risk in LS by decreasing microsatellite instability, a key driver of LS-related cancer. This study evaluates 5-ASA's efficacy as a tolerable chemopreventive d
Background: Hemophilia B is a genetic bleeding disorder caused by a deficiency of clotting factor IX, which presents unique challenges in clinical management. Advances in therapeutic strategies for hemophilia B have significantly improved patient outcomes but have also necessitated ongoing education for healthcare professionals. This illustrated review provides an overview of the challenges and op
Two new endemic species from Bolivia, Gomphrena vallegrandensis T. Ortuño & S. Lozada-Gobilard and Gomphrena palmariensis T. Ortuño, J. Gutiérrez. & Montesinos, are described and illustrated. The former only occurs in the native open natural grassland close to the Tucuman forest (Prov. Vallegrande), and the latter is restricted to the areas with rock outcrops in the subpuna close to the in
The package ParSeq is a Python software library for Parallel execution of Sequential data analysis. It implements a general analysis framework that consists of transformation nodes - intermediate stops along the analysis propagation to visualize data, display status and provide user input - and transformations that connect the nodes. ParSeq imports data into an adjustable data model - a collection
Obesity represents a global health challenge, with a critical and urgent need for long-term, sustainable management strategies. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. At first approved for the treatment of type 2 diabetes mellitus, tirzepatide represents one of the latest clinically approved and commercia
In this paper, we study the function spaces D(μ) by Richter (1991) and Aleman (1993), and Dμ→ by Rydhe (2019). It is known that the forward shift Mz is bounded and expansive on D(μ), and therefore D(μ) coincides with a de Branges-Rovnyak space H[B]. We show that such a B is rational if and only if μ is finitely atomic, and this happens exactly when the corresponding defect operator has finite rank
In this article, I explore the assigned role of interpreters in journalism training programmes in Vietnam, focusing on two media aid projects funded by the Swedish International Development Cooperation Agency (Sida): the Local Radio Project and the Further Training of Journalists programme. The study is based on qualitative analyses of project documentation and interviews with former trainers. A t
ImportanceThe management of complications following oral cavity squamous cell carcinoma (OCSCC) surgery can be challenging. Previous studies show conflicting results on complication risks after preoperative radiotherapy (RT), necessitating a randomized controlled trial (RCT).ObjectiveTo compare early complications during hospitalization for OCSCC surgery between patients receiving preoperative acc
