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We demonstrate self-compression of 173 fs pulses centered at 1030 nm down to 19.5 fs through electro-optic phase modulation by the phonon-polariton waves generated in a phase-matched intra-pulse difference-frequency mixing.
Two-dimensional terahertz strong-field spectroscopy reveals wave-mixing processes up to eighth order in a free-running quantum cascade laser, unravelling its sub-cycle gain dynamics and nonlinearities in a regime of negative absorption.
We discuss basic pulse energy scaling principles for multi-pass cells (MPCs) and introduce a novel multi-pass cell type which we employ to numerically predictpost-compression of 125 mJ pulses using a 2 m setup.
BACKGROUND AND OBJECTIVES: The existence of social problems, crime, and a diminishing sense of community are acknowledged challenges to residents of deprived neighborhoods. In research on deprived neighborhoods in Sweden, the perspectives of young residents and adults of working age dominate. This study explores how older adults in deprived neighborhoods in Sweden experience crime and disorder, an
BackgroundMedication treatment can reduce morbidity but can also cause drug-related problems (DRPs). One method to identify and solve DRPs is medication reviews (MRs) that are aimed at increased patient safety and quality in drug treatment. In Skåne county, Sweden, a well-established multi-professional model for MRs in nursing homes is practiced. However, a demand for MRs regarding community-dwell
Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognosis. However, a better definition of GSC subpopulations, especially at the surgical resection margin, is warranted for improved oncological treatment options. T
The decarbonisation of energy systems is leading to a reconfiguration of the geographies of energy. One example is the emergence of community energy, which has become a popular object of study for geographers. Although widely acknowledged to be a contested, capacious, and flexible term, “community energy” is commonly presented as singular, bounded, and localised. In this paper, we challenge this c
In recent years the term ‘energy democracy’ has become increasingly popular, especially in the context of aspirations for a low-carbon transition that include wider socio-economic and political transformation. The emergence of ‘energy democracy’ is thus part of a broader trend in research and practice which has sought to foreground the 'stuff’ of politics. Yet, unlike the more academically develop
There is a growing ‘energy democracy’ (ED) movement which regards the transition to renewable energy as an opportunity for socio-economic transformation, as well as technological innovation. The literature on ED tends to associate greater democratic control of energy systems with increased community control over the means of energy generation and distribution. Nonetheless, this literature often as
Using a case study of the Búrfell wind farm project, a large wind farm proposed in the Central Highlands of Iceland, the authors attempt to provide new insights into the factors shaping subjective landscape perceptions and attitudes to renewable energy developments, and into alternative methods that may be used for their assessment. The research was based on an on-site visit and actual experience
For rural communities, energy projects can provide a host of benefits, and yet also be a source of significant conflict. Place attachment has become an increasingly popular concept for understanding local responses to large scale renewable energy installations. However, there has been significantly less attention paid to how place attachment influences local responses to community-led developments
The community energy sector is widely understood to be a pluralistic sector, encompassing a broad range of aims, motivations, and practices. This heterogeneity is, however, still not very well understood. Dominant analytical frameworks in the study of energy geographies offer little in the way of exploring the diversity of motivations, visions, and social relations that are present within the comm
This study provides insights into the external powers that can influence business leaders' communication on sustainability. It shows how the socio-political context manifested in national and transnational policies, regulations and other socio-political events can influence the CEO talk about sustainability. Design/methodology/approach: This study adopts an interpretative and qualitative method of
The incidence of Human Papillomavirus positive (HPV+) tonsillar cancer has been sharply rising during the last two decades. Myeloid cells represent an appropriate therapeutic target due to their ability to orchestrate antigen-specific immunity within the tonsil, the availability of viral antigens, and the proximity of the tumor and the underlying lymphoid tissue. However, the interrelationship of
This study contributes to the sparse literature on differences between public and private primary care practices (PCCs). The purpose was to explore if differences in performance and characteristics between public and PCCs persist over time in a welfare market with patient choice and provider competition, where public and private providers operate under similar conditions. The analysis is based on
Tonsillar cancer (TC) is a subset of head and neck cancer (HNC). TC incidence is sharply rising due to an increased prevalence of human papillomavirus (HPV) infection in the western world. Currently HPV status is considered during clinical staging due to its positive association to patient prognosis. Presumably, the relation between HPV and patient survival is dependent on the generation of an eff
The 68-kDa homodimeric 3C-like protease of SARS-CoV-2, Mpro (3CLpro/Nsp5), is a key antiviral drug target. NMR spectroscopy of this large system proved challenging and resonance assignments have remained incomplete. Here we present the near-complete (>97 %) backbone assignments of a C145A variant of Mpro (MproC145A) both with, and without, the N-terminal auto-cleavage substrate sequence, in its na
