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Understanding inhomogeneous MT (ihMT) in multi-parameter mapping of human brain: Towards larger ihMT, higher resolution, and influence of T1d

Inhomogenous Magnetization Transfer (ihMT), the differential response to irradiation at single and dual frequency offsets, is more complex than MT approaches. Expressing ihMT in terms of MT-saturation (ihMTsat) is a first step to quantification as it corrects for underlying T and B . Larger ihMTsat was observed for smaller frequency offsets, which is explained using MTsat as proxy for bound pool s

Mapping the architecture of the temporal artery with photoacoustic imaging for diagnosing giant cell arteritis

Photoacoustic (PA) imaging is rapidly emerging as a promising clinical diagnostic tool. One of the main applications of PA imaging is to image vascular networks in humans. This relies on the signal obtained from oxygenated and deoxygenated hemoglobin, which limits imaging of the vessel wall itself. Giant cell arteritis (GCA) is a treatable, but potentially sight- and life-threatening disease, in w

The present is a knife’s edge : St. Augustine’s philosophical presentism and the politics of expectation

The ways in which expectations for the future shape how actors and organizations make sense of the present has received growing interest and attention among science and technology scholars – with particular attention being paid to the role of expectations and prediction making in technology and finance. Nevertheless, while the imaginaries involved in the futures described by tech-entrepreneurs and

Sequence of flexion contracture development in the lower limb : a longitudinal analysis of 1,071 children with cerebral palsy

Background: To prevent severe contractures and their impact on adjacent joints in children with cerebral palsy (CP), it is crucial to treat the reduced range of motion early and to understand the order by which contractures appear. The aim of this study was to determine how a hip–knee or ankle contracture are associated with the time to and sequence of contracture development in adjacent joints. M