High Migratory and Cytotoxic Capability of CD56bright NK Cells in a Blood-Brain-Barrier in Vitro Model The blood brain barrier (BBB) is a tight structure in the Central Nervous System (CNS) that restricts the entry of immune cells. This restriction is regulated by different components such as endothelial cells, tight junction proteins and other cells such as pericytes, astrocytes and neurons. Nat

Development of a successful prophylactic or therapeutic treatment for active Tuberculosis (TB) has been hampered by the bacilli’s ability to evade, tolerate, subvert host immunity and persist in a hypoxic intracellular niche. Upon infection with M. tuberculosis (Mtb), there is an increased demand for metabolites by cells to respond to the robust immune activation, which is met with a shift of meta

Skolfrånvaro eller skolk är ett fenomen ofta kopplat till olika orsaker som stress, social exkludering, förlust av självförtroende och självkänsla samt även drogmissbruk, något som har långtgående konsekvenser för individen och i förlängningen samhället. Huvudintresset i denna studie var att hitta och förstå relationerna mellan global självkänsla och kompetensbaserad självkänsla (CBSE), skolfrånvaSchool absenteeism is today a worldwide phenomenon linked to a plethora of issues with long term consequences on both individuals and society, such as stress, social exclusion, loss of confidence and self-esteem and even drug abuse. This study investigates the interrelationship between global self-esteem and competence-based self-esteem (CBSE), absenteeism and academic performance as well as stres

Workplace health promotion has been gaining a lot of interest, as it could benefit both employees and organizations. Results and conclusions are, however, still ambiguous and there is not much known about how employees’ participation and perception affect positive work outcomes. The present research aims to examine the link between employees’ participation and perception of workplace health promot

Kontrollera Cellens Kvalitetskontroller Vilka proteiner påverkar bildandet av de giftiga aggregationer som kan ses i hjärnan vid Parkinsons sjukdom? Och vilken roll kan cellens egna kvalitetskontroller spela i bekämpandet av dessa giftiga aggregationer? Vår forskargrupp har utvecklat en ny typ av modell för att studera grundläggande processer som kan ligga bakom en av våra vanligaste obotliga neu

Krillens barnkammare hotas av smältande havsis i Antarktis I den västra delen av den antarktiska halvön smälter havsisen. Den delen av södra oceanen är känd för sin stora rikedom och mängd av antarktisk krill, Euphausia superba. Krillen är beroende av havsisen för föda och beskydd. Den globala uppvärmningen försämrar krillens lekområden. Man ser nu en nedgång i krillbeståndets storlek och krillenAntarctic krill, Euphausia superba, a polar ocean specialist, thrives in the Antarctic severe physical conditions. The krill life cycle consists of strategies that have enabled and supported the species’ dominance of the Antarctic Ocean. Sea Ice extent and duration creates condition that are crucial for survival of the Furcilia larvae. The species has flexibility to food resources and is omnivorou

In the age of ever-growing technological advancements, delegating some of the inherently human tasks to smart machines is becoming more and more common. The possibly new wave of industrialization – Industry 4.0 – is comprised of interconnected smart technologies that could automate parts of the production and decentralize the decision-making process. The associated efficiency has prompted business

Möjligheten att få studera medlemsminskningen i Svenska kyrkan har fångat mitt intresse, och utgör utgångspunkten för denna uppsats. Studiens syfte är att utforska olika förklaringar till medlemsminskningen. Den valda metoden för denna uppsats är kvalitativ istället för kvantitativ, då uppsatsämnet tjänar på att kunna belysas med mer detaljerade svar. Studiens upplägg har baserats på Svenska kyr

There is an urgent need for change within the garment sector as it continues to massively contribute to the climate crisis. This need for change has led to a growing interest in collaborative fashion consumption and its possibilities to support sustainable consumption within the garment sector. This research explores whether the two identified models of collaborative fashion consumption, business

This thesis explores the experiences of international and domestic higher education students in the U.S. during the 2020 COVID-19 pandemic. By using an Interpretative Phenomenological Analysis (IPA) approach the aim of the thesis, in the first place, is concerned with students’ experience during national and global lockdowns with social distancing and isolation and, secondly, with the structural c

Syftet med denna studie är att bidra med en ökad förståelse för hur digitaliseringen har påverkat butiker inom sportbranschen. Detta har studerats genom att undersöka vilka utmaningar sportbutiker ser med digitaliseringen samt på vilka sätt sportbutiker tar sig an dessa utmaningar med hjälp av en omnikanal-strategi. Med bakgrund i att teknologin utvecklas och att människor blir allt mer styrda av

This project aims to open a dialogue on the role of the border in todays society. Computational design and emerging 3d fabrication technology will be implemented as a tool to create a border typology modeled after the abundant, productive hedgerows found in nature. Experimentation will delve into the possibilities of digital design and how to manipulate and control algorithmic processes to grow a

This thesis explores access to central knowledge platforms of middle-class parents within the context of Copenhagen. Through a qualitative approach, including interviews and participant observation, access to the 3 main knowledge platforms is explored: firstly, direct contact with municipality health care visitors in the home; secondly, maternity groups constructed according to homogenic ideals an

Case management is an intervention and a profession (case manager or personal representative) in Sweden, working with clients with mental disabilities and/or severe substance abuse problems. When established here in 1995 it relied on research from other countries and thus on other legislative regulations and local social situations. Moreover, theNational Board of Health and Welfare'slatest fol

Within the international human right law scholarship and philosophy of human rights, there is no clear picture how human rights, old and new, emerge from the ground, from the small idea that a new human right is needed. There is no theory why and how human rights emerge, as well as there is no methodology how the idea could come through the process of development, then emerge as a human right in t

The concepts of “Judeo-Bolshevism” (used between approx. 1917-1945) and “Cultural Marxism” (used 1973-today) seem to have a lot in common: both are derogatory concepts used to classify the political opponent. This thesis aims to create a first insight into the meaning of the concepts of Judeo-Bolshevism and Cultural Marxism and the relation between them, with methods derived from Conceptual Histor

This research explains the distribution of rewards within the innovative economic practice of online motorcycle taxi services in Indonesia. Those analyzed are online transportation platforms and their driver-partners. These two are analyzed using the theoretical framework of the innovation economy, which is conceptualized as cumulative, uncertain, and collective economic processes by Mariana Mazzu

This essay focuses on the phenomenon of the new man and new masculinity and how it is used and described in fashion articles. The phenomenon points at something new but within a historical context we see that the new man goes back in history. The aim of this essay is to find what the new man and its new masculinity is today according to fashion journalism. The empirical data consists of ten fashio

Syftet med den här studien har varit att tolka hur unga män i åldern 18–24 år utifrån emotionssociologisk synvinkel upplever känslan av rädsla och trygghet, och hur de utifrån ett genusperspektiv talar om känslor. Vidare har studien undersökt vad som bidrar till de unga männens känsla av rädsla och trygghet. Detta har gjorts genom en kvalitativ metod i form av fem semi strukturerade intervjuer med