Objectives: To report the long-term outcomes from a longitudinal psychosocial study that forms part of the ‘Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted Screening in men at higher genetic risk and controls’ (IMPACT) study. The IMPACT study is a multi-national study of targeted prostate cancer (PrCa) screening in individuals with a known germline pathogenic varia

Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor condition for multiple myeloma (MM). We hypothesized that analyzing haplotypes might be more useful than analyzing individual SNPs, as it could identify functional chromosomal units

Students’ learning developments of limits were studied in a calculus course. Theiractions, such as problem solving and reasoning, were considered traces of theirmental representations of concepts and were used to describe the developmentsduring a semester. Several students went through the course with a vague conception of limits which in some cases was wrong. A higher awareness about their mental

Most concepts taught in a basic analysis course at university are somewhatfamiliar to the students. They use their representations from prior experiences toform new knowledge about the concepts. Fifteen students’ were examined at thebeginning of a basic university course in analysis. Their pre-knowledge wassometimes vague and even wrong, often due to intuitive perceptions.

The paper presents a work in progress which is part of a larger study. Studentslearning analysis was investigated with the aim to find out how their concept images changed from the beginning of an analysis course to a year after the course. Their links between concepts were studied after the year had passed. The influence of the students’ pre-knowledge was durable and sometimes prevented students

A group of pre-service teachers were studied from two social practices, as teachers and as students. Their perceptions of mathematics concepts and beliefs about the mathematics teacher role were studied through questionnaires, interviews and classroom observations. Three students were selected as cases in this paper where their links between the concepts limits, derivatives, integrals and continui

The aim of this three-year study is to further contribute to the understanding of how relations between Reality – Theoretical models – Mathematics are communicated in Swedish upper-secondary physics. A developed analytical framework (Hansson, Hansson, Juter, & Redfors, 2015; 2019) is used to focus the analysis of the classroom communication on relations made (by teachers and students) between

BACKGROUND: Previous studies have demonstrated an association between transplantation rate per center and postoperative mortality after heart transplantation. In 2011, Sweden centralized heart transplants and waiting lists, reducing the number of centers from 3 to 2. We aimed to assess the active waiting time and pre- and post-transplant mortality before and after centralization.METHODS: Heart tra

To examine whether the level of genetic risk in psychiatric disorders impacts the social functioning of affected individuals, we examine the relationship between genetic risk factors for major depression (MD), anxiety disorders (AD), bipolar disorder (BD), non-affective psychosis (NAP), alcohol use disorder (AUD), and drug use disorder (DUD) in disordered individuals and five adverse social outcom

Purpose: To investigate the contributors to self-rated health in people with late-stage Parkinson’s disease (PD) and cognitive impairment. Methods: A secondary analysis of baseline data from the international Care of Late-Stage Parkinsonism (CLaSP) cohort study was conducted. Participants with PD and either dementia or mild cognitive impairment or MMSE < 24/30 in the absence of major depression we

Proof logging in constraint programming is an approach to certifying a conclusion reached by a solver. To allow for this, different propagators must be augmented to produce justifications for any inferences they make, so that an independent proof checker can certify correctness. The Circuit constraint is used to enforce a Hamiltonian cycle on a set of vertices, e.g. for vehicle routing. Maintainin