Neovascularization is implicated in the pathology of retinopathy of prematurity (ROP), diabetic retinopathy (DR), and age-related macular degeneration (AMD), which are the leading causes of blindness worldwide. In our work, we analyzed how heme released during hemorrhage affects hypoxic response and neovascularization. Our retrospective clinical analysis demonstrated, that hemorrhage was associate

This paper investigates the factors affecting evacuation behaviour of tourists in wildfire scenarios by conducting a scoping review using the Preferred Reporting Items for Systematic reviews and Meta-Analysis approach - here using only its extension for scoping reviews. A total of 524 scientific papers were identified in the Web of Science and Scopus and 23 studies were fully reviewed. Key variabl

Two-dimensional neuronal cultures have a limited ability to recapitulate the in vivo environment of the brain. Here, we introduce a three-dimensional in vitro model for human glia-to-neuron conversion, surpassing the spatial and temporal constrains of two-dimensional cultures. Focused on direct conversion to induced dopamine neurons (iDANs) relevant to Parkinson disease, the model generates functi

Alzheimer's disease (AD) is the most common neurodegenerative disease and is characterized by the aggregation of β-amyloid (Aβ) and tau in the brain. Breakthroughs in disease-modifying treatments targeting Aβ bring new hope for the management of AD. But to effectively modify and someday even prevent AD, a better understanding is needed of the biological mechanisms that underlie and link Aβ and tau

Om Klostergatans betydelse som offentlig arena, mötes-, umgänges- och uppvisningsplats i Lund, särskilt bland stadens studenter, från sent 1800-tal till mitten av 1900-talet. Med exempel ur memoarer, skönlitteratur och samtida press.

Tio personporträtt av mer eller mindre bortglömda lundaakademiker - studenter och lärare - verksamma mellan 1600-talet och 1900-talets första hälft.

EU law has developed with close ties to economic growth, and relatedly, various scholars have historically expressed critiques which would today be considered part of the Law and Political Economy approach. What is starkly absent from the relevant critiques is the way in which EU law regulates the migration phenomenon and its relation to the market. Migration law scholarship has been focusing on t

Microplastics (MP) have emerged as significant global pollutants, garnering considerable attention from both the scientific community and the public. The significance of microplastic research lies in its capacity to inform effective pollution control strategies and mitigate associated environmental and health risks. The review illuminated the complexities and challenges inherent in analyzing micro

Heavy metal (HM) pollution remains a pressing global concern, affecting soil regarding food safety, and negatively influencing the UN Sustainable Development Goals (SDGs). We investigated the efficacy of untreated cypress biochar (UCB) and Ca-modified cypress biochar (MCB) in mitigating HM contamination and enhancing growth across native and contaminated soils (40 mg/kg) in carrot pot experiments.

Groundwater is becoming increasingly important as surface water is decreasing and becoming more and more polluted. In particular, rural areas in the arid region of Central Asia face problems with both water quantity and quality. In view of this, we investigated the drinking water quality in the Maysky district in the Pavlodar region, Kazakhstan. The organoleptic properties, together with microbiol

Study region: The NekooAbad Irrigation District in central Iran faces challenges due to inefficient surface water distribution. 82 million m3 of groundwater is extracted annually from 15,000 tube-wells, leading to decreased groundwater levels and increased energy consumption of 234 million kWh per year. Study focus: This study explores implementing automation in surface water distribution to reduc

As video and computer games get increasingly more advanced, the immersive experience for the player of these games also follows this trajectory. In these games, one aspect that has been explored to the greatest extent is that of choice and player agency. Often, these choices and acts are of a moral character, whether it be choosing what to do on an ambiguously formulated questline with multiple br

Det tog många år innan Svenska kyrkan på nationell nivå kunde redovisa statistik om delar av församlingarnas diakonala arbete. Införandet av diakonistatistik har mött motstånd, men flera aktörer samlar också egen statistik vid sidan av den nationella verksamhetsstatistiken.

ObjectiveIndividuals with neurodevelopmental and/or neurocognitive disorders (NNDs) have complex, long-term care needs. In Bangladesh, India, and Pakistan, informal carers shoulder the responsibility and strain of providing care for people with NNDs. Intense care demand, societal and cultural care expectations, and lack of support infrastructure often lead to psychosocial strain in this inadequate

The initial interview is a critical moment in the relationship between the patient and the palliative care team. Good communication skills, while always important in clinical medicine, are especially indispensable in this context, where a life-threatening illness and associated fear, anxiety, sadness, and hope can make for a challenging clinician-patient relationship. When done expertly, the initi

Vårt bidrag tar utgångspunkt i hur innovativa avlopps- och vattenhanteringspraktiker samspelar i en urban kontext. Det empiriska materialet har hämtats från ett tvärvetenskapligt forskningsprojekt om innovativ vattenhantering i en stad i Sverige. Artikeln analyserar på ett övergripande plan samtida idéutveckling vad gäller återvinning av avloppsvatten och hur denna idéutveckling producerar olika f

Background Implementation of evidence-based practice (EBP) in child and adolescent mental health services (CAMHS) is a priority to improve service delivery and outcomes. Clinicians’ EBP attitudes are likely to play a crucial role in implementation but are poorly understood. This study aimed to assess variation in EBP attitudes in a large national sample of CAMHS clinicians in Sweden, and to compar

Though augmented reality (AR) is increasingly adopted in marketing, its capacity to foster consumers' engagement and attachment remain tenuous, exposing an important literature-based gap. Addressing this gap, we deploy social presence theory and luxury consumption theory to develop and test a model that proposes that consumers' engagement with AR-deploying luxury brands drives the development of t