Popular Abstract in Swedish Avhandlingen beskriver forskningen kring miniatyriserade enzymreaktorer - nyckelkomponenter i system för diabetsövervakning. Målet är att systemet kontinuerligt och under flera dagar skall kunna mäta glukosstatus hos bäraren. Provtagningstekniken för systemet är mikrodialys; en prob instucken i bukfettvävnaden ger ett prov som innehåller glukos. Analysen av detta prov sThe development of a miniaturised silicon wafer integrated enzyme reactor is described. The reactor was micromachined by anisotropic wet etching of (110) silicon. The enzyme glucose oxidase (GOx) was coupled to the reactor surface with standard methods of immobilising enzyme to silica. The glucose turn-over rate was monitored following a colourimetric assay. The advantage, in terms of high surface

Microfluidic systems have become one of the most interesting fields in the research of chemical analysis. Miniaturized systems exhibit numerous practical advantages when compared with traditional batch-scale synthesis such as lower sample volumes, increased control of the reactions and higher sample throughput. This thesis describes the development and applications of a parallel channel microreact

Introduction to the work of Australian poet Dorothy Porter, and her verse novel The Monkey's Mask.

The Cauchy problem for linear constant-coefficient hyperbolic systems ut + ∑j A(j)uxj = (1/δ)Bu + Cu in d space dimensions is analyzed. Here (1/δ)Bu is a large relaxation term, and we are mostly interested in the critical case where B has a non-trivial null-space. A concept of stiff well-posedness is introduced that ensures solution estimates independent of 0 < δ 1. Stiff well-posedness is charact

The recently finished EU funded project MACIS reviewed observed and projected climate change impacts on biodiversity. It assessed mitigation and adaptation options. It also reviewed and developed methods to assess future impacts of climate change on biodiversity including the identification of policy options to prevent and minimise these impacts.

Binding of urokinase plasminogen activator (uPA) to its cellular receptor, uPAR, potentiates plasminogen activation and localizes it to the cell surface. Focal plasminogen activation is involved in both normal and pathological tissue remodeling processes including cancer invasion. The interaction between uPA and uPAR therefore represents a potential target for anti-invasive cancer therapy. Inhibit

Management of oropharyngeal swallowing dysfunction often requires both a clinical and an instrumental examination. A videofluoroscopic swallowing study is an instrumental examination that often could be a good option and a very useful tool for the swallowing clinician. At Skåne University Hospital, Malmö, Sweden, the name of such examination is therapeutic videoradiographic swallowing study (TVSS)

Operating the HCCI engine with dual fuels with a large difference in auto-ignition characteristics (octane number) is one way to control the HCCI operation. The effect of octane number on combustion, emissions and engine performance in a 6-cylinder SCANIA truck engine, fuelled with n-heptane and isooctane, and running in HCCI mode, are investigated numerically and compared with measurements taken

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Parents are the primary support providers for adolescents with disabilities, their health and wellbeing is therefore of great importance when planning for youths' transition into adulthood. The aim of this study was to gain a deeper understanding of how parents of adolescents with cerebral palsy (CP) experience their own health and wellbeing and their needs for support during the adolescent's tran

Vildagliptin is a potent, selective and reversible inhibitor of dipeptidyl peptidase-4 (DPP-4), the enzyme responsible for rapid inactivation of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). GLP-1 and GIP are important for the maintenance of normal glucose homeostasis as they enhance the sensitivity of insulin (beta-cell) and glucagon (alpha-cell)