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An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions

Specific granule protein of 28 kDa (SGP28), also termed cysteine-rich secretory protein 3 (CRISP-3), is a glycoprotein that belongs to a family of cysteine-rich secretory proteins (CRISPs). SGP28 was originally discovered in human neutrophils, but transcripts are widely distributed in exocrine glands (salivary glands, pancreas, and prostate) and also found at lower levels in epididymis, ovary, thy

Continuous infusion of cholecystokinin leads to down-regulation of the cholecystokinin-A receptor in the rat pancreas

BACKGROUND: Infusion of sulphated cholecystokinin-8 (CCK-8S) in rats transiently increased the proliferation of pancreatic acinar cells, whereas the CCK-A receptor antagonist devazepide decreased such proliferation. This effect ceased after 3 days. CCK-8S or devazepide injected twice daily induced a persistent effect on the cell proliferation involving the major cells of the exocrine pancreas. The

Autonomic and peripheral nerve function in early diabetic neuropathy. Possible influence of a novel aldose reductase inhibitor on autonomic function

Autonomic and peripheral nerve functions as well as the possible short-term effect of a novel aldose reductase inhibitor (ARI) on neuropathy were evaluated in 30 male type I diabetics (age 25-44 years, mean 34; duration of diabetes 10-20 years, mean 34) with neurographic signs of peripheral neuropathy (PN). Autonomic neuropathy (AN) was established by the heart rate reactions to deep breathing (E/

Dietary fibre enrichment, blood pressure, lipoprotein profile and gut hormones in NIDDM patients

The influence of a beet-fibre enriched diet (mean 40 g FibrexR, 27 g dietary fibre per day) on blood pressure, plasma lipoproteins and glycaemic control was studied in 12 non-insulin-dependent diabetic (NIDD) patients. The effect on gastrointestinal hormones was also investigated. Beet-fibre and control diets were given in randomized order for 8 weeks each. During the beet-fibre diet the systolic

Flame propagation visualization in a spark-ignition engine using laser-induced fluorescence of cool-flame species

The flame propagation in a spark-ignition engine has been studied using laser-induced fluorescence (LIF) of species formed during the first ignition stage of hydrocarbon combustion. The detected two-dimensional LIF images showed the distribution of unburned regions. For the excitation, two Nd:YAG lasers operating at 355 mn were used for two consecutive measurements within the same engine cycle wit

Seven-year Study of the Effect of Silica Fume in Concrete.

In this article an experimental and numerical study of the long-term interaction between silica fume and Portland cement in concrete subjected to air, water or sealed curing is outlined. For this purpose about 250 kg of eight qualities of each concrete were studied at 4 different ages each over a period of 7 years. Parallel studies of strength, hydration and internal relative humidity were perform

Food sources of carbohydrates in a European cohort of adults.

Objective: To describe the average consumption of carbohydrate-providing food groups among study centres of the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Of the 27 redefined EPIC study centres, 19 contributed subjects of both genders and eight centres female participants only (men, n=13 031; women, n=22 924, after exclusion of subjects under 35 and over 74 years

Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting.

SUMMARY: When Efexor(R) (venlafaxine) became available in Sweden, a therapeutic drug monitoring (TDM) service was developed in the authors' laboratory. This analytical service was available to all physicians in the country. From March 1996, to November 1997, 797 serum concentration analyses of venlafaxine (VEN) and its main metabolites, O-desmethylvenlafaxine (ODV), N-desmethylvenlafaxine (NDV), a

Unification and Conflict. The Church Politics of Alonso de Montúfar OP, Archbishop of Mexico, 1554-1572.

Popular Abstract in Swedish I centrum för min avhandling står den spanske dominkanen Alonso de Montúfar (ca.1489-1572) som mellan 1554 och 1572 var ärkebiskop av Mexiko. I synnerhet har jag studerat hur ärkebiskop Montúfar ville att kyrkan skulle organiseras (hans kyrkovision) och hur han försökte förverkliga sin vision (hans kyrkopolitik). Montúfar kom till Mexiko drygt trettio år efter den spanThis dissertation focuses on Archbishop Alonso de Montúfar OP (ca. 1489-1572). It seeks to explore two decades of sixteenth century Mexican Church History mainly through the study of documents found in Spanish and Mexican archives. Born outside Granada in Southern Spain, just after the conquest from the Muslims, Alonso de Montúfar assumed teaching and leading positions within the Dominican order.

Improvement of peripheral nerve function after institution of insulin treatment in diabetes mellitus. A case-control study

The influence of improved diabetic control on peripheral nerve function was studied before and 3-4 months after institution of insulin treatment in 22 diabetics unsatisfactorily controlled by oral hypoglycemic agents. After institution of insulin treatment, diabetic control was improved as demonstrated by decreasing levels of HbA1. There was an overall tendency towards improvement of motor and sen

Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension.

Objective Obstructive sleep apnoea (OSA) confers a risk of hypertension and cardiovascular complications. Both the renin-angiotensin-aldosterone system and OSA are important determinants of blood pressure, but it is not fully known how they interact. The aim of this study was to explore the interaction between the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and O

Trellis based variable rate residual image coding over noisy channels

We consider the lossy image compression problem and propose a model-residual approach. Polynomial basis images encode the model image and powerful new trellis codes quantize the residual part. A simple bit allocation scheme determines the residual bit rates and a variety of rates are attainable without entropy coding. The trellis structure is also used to form a joint source and channel coding sch

När ett plus ett blir tre - om samverkan inom kommunal avfallsverksamhet

Den övergripande ambitionen i denna rapport är att sprida lärdomar och konkreta exempel på kommunal samverkan inom avfallssektorn. Konkret är det tre områden som står i fokus: • Att beskriva olika former av samverkan utifrån ett antal praktiska exempel. • Att analysera vilka typer av fördelar samverkan kan ge • Att beskriva hur parterna går tillväga när de samverkar, dvs samverkansprocessen. F