Identification of Modified Peptides using Open and Conventional Search Engines
Mass Spectrometry- based proteomics has matured to an analytical tool applicable in many areas of life science. Although, limitations remains where much focus has been towards the development of search engines to more accurately identify peptides in fragmentation spectra. This report aims to investigate four search engines; MSGF+, Andromeda, MSFragger and pFind in order to assess the advantages an