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The protein Painless is an ion channel coupled receptor that is present in the mosquito Aedes aegypti transmitting yellow fever. The protein is activated by noxious heat. It has been a long-term goal to determine the protein structure and consequently be able to develop a mosquito repellant. The aims of the thesis were to purify and isolate heterologously expressed Painless from yeast cells and ex

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This ethnographic study takes a phenomenological approach to examining the experiences of urban explorers in Sweden. Data collection took place in Skåne and Stockholm between October 2025 and February 2026, using the qualitative methods of semistructured interviews and participant observation. Urban exploration encompasses a wide range of practices; this thesis centers around its core aspect of vi

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This thesis investigates non-intrusive Room Impulse Response (RIR) estimation using music as an excitation signal in an acoustic environment with background noise present. The work studies the structure of room impulse responses, sparse background noise, babble noise, and music excitation signals in the context of RIR estimation. Building on the recently proposed AnyRIR estimator, which explored s

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α-CGRP 8-37 is a peptide fragment of calcitonin gene-related peptide and is commonly used as a CGRP antagonist in pharmacological research. CGRP signaling has been discussed in relation to neuroimmune mechanisms in psoriasis, but a practical development of α-CGRP 8-37 requires analytical methods and formulation strategies that can handle peptide instability, adsorption, and matrix effects. The aim

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The increasing demand for electric vehicle charging stations creates new challenges for electric grid planning. This thesis proposes a framework for forecasting realistic 24-hour peak load profiles for new direct current fast-charging stations without historical observations. The method combines $K$-means clustering of existing stations’ hourly load patterns and random forest models that predict b

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Fingerprint recognition has become a popular authentication method in modern smartphones, replacing traditional passwords and PINs. However, smartphone fingerprint sensors are small and capture only partial fingerprints with limited resolution. Combined with varying image quality and inconsistent finger placement, multiple images must be stored per user to ensure reliable authentication. During ve

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This study explores how knowledge, communication, and influence are organized within the consultation reports of the Swedish urban planning practice. The study is based on collaborative planning theory and analyses the extent to which the consultative process is grounded in collaborative or performance- or criteria-driven planning logic. Through a qualitative content analysis of consultation repor

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This thesis explores how immersive virtual reality can be designed to support emotional engagement, relaxation, and a sense of connection to nature. Based on experience design and gesture interaction theory, this project developed a VR experience titled "Night Journey". In this experience, users can explore a virtual nature and interact with a responsive ecosystem through natural body ge

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This study investigates how varying hyperparameters of the Synthetic Minority Over-sampling Technique (SMOTE) affects the stability of model explanations produced by SHapley Additive exPlanations (SHAP) and Local Interpretable Modelagnostic Explanations (LIME). By using an eXtreme Gradient Boosting (XGBoost) classifier trained on 11 medical datasets with varying imbalance ratios, four SMOTE parame

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Introduction: Liquid-liquid phase separation (LLPS) is a process that occurs often in biological environments, and elastin is a protein that utilizes it to form elastic fibres. Understanding elastin’s LLPS is very helpful for creating new biomaterials and researching diseases, where LLPS occurs. Background: The coacervation of elastin is widely researched, but the combination effects of salt, hea

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In 2025, the unauthorized release of four lynx in Scotland sparked widespread media speculation about “guerrilla” rewilding. Drawing on political ecology and environmental justice, this thesis applies a critical discourse analysis to investigate how media outlets framed lynx reintroduction following the unauthorized release. The findings show that media coverage constructs rewilding as contentious

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This study examines how tourism affects and reshapes residents’ identities and sense of place in the Sanno-chiku of Takayama City in Gifu Prefecture, Japan. This study focuses on residents’ lived experiences and discusses tourism through the ideas and concepts of place, sense of place, identity, mobility, and commodification. This study asks two research questions: 1) How does tourism shape local

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Polyhydroxyalkanoate (PHA) synthases (PhaC) are the pivotal biocatalysts governing the biosynthesis of biodegradable polyesters. Current research on their structure and mechanisms remains limited, and the chemical mechanisms of all PHA synthases are still under debate. Despite some speculation, further physicochemical studies are needed to understand their structure and function. The primary obje

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This master’s thesis explores the ethnic self-identification of young Russian speakers from Estonia, as well as their sense of belonging to Estonia and the Estonian society. The research focuses on an understudied group of younger people who did not experience the life under the Soviet Union, which leads to them not sharing the identification of a “Soviet citizen” that was common for the older gen

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Ring voltage-controlled oscillators (Ring VCOs) are widely used in clock generation because of their compact area and wide tuning range, but their high inherent phase noise limits their application in high-performance systems. To address this, this thesis presents a low-power dual-path sub-sampling PLL (SSPLL) covering a wide frequency range from 2GHz to 4GHz. To effectively suppress the phase noi

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Disasters are social and political constructs, and their impacts are shaped by people’s action and inaction. How we allocate time, money, and resources matters in shaping the outcomes post-disaster, especially of those most vulnerable. While the lesbian, gay, bisexual, transgender, and queer (LGBTQ+) community is an understudied demographic in disaster research, existing studies show that LGBTQ+ p

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Att leva med klusterhuvudvärk innebär att hantera återkommande smärtanfall och samtidigt leva med osäkerheten kring när nästa anfall kan inträffa. Denna uppsats analyserar klusterhuvudvärk som ett temporalt livsvillkor snarare än enbart som ett neurologiskt smärttillstånd. Med utgångspunkt i tio kvalitativa intervjuer med personer som har diagnostiserad klusterhuvudvärk undersöks hur återkommande