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Deep learning-based evaluation of normal bone marrow activity in 18F-NaF PET/CT in patients with prostate cancer

Purpose: Bone marrow is the primary site of skeletal metastases in prostate cancer. 18F-sodium fluoride (NaF) can be used to detect malignant activity, but also identifies irrelevant degenerative cortical uptake. Normal radiotracer activity in solely the marrow has yet to be described and could be a first step towards automated tumor burden calculation as SUV thresholds. We aimed to investigate no

Transatlantic multicenter study on the use of a modified preloaded delivery system for fenestrated endovascular aortic repair

Objective: Analyze the outcomes of endovascular complex abdominal and thoracoabdominal aortic aneurysm repair using the Cook fenestrated device with the modified preloaded delivery system (MPDS) with a biport handle and preloaded catheters. Methods: A multicenter retrospective single arm cohort study was performed, including all consecutive patients with complex abdominal aortic aneurysm repair an

Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer's Disease at the Memory Clinic : The BEAT-IT Study

Background: Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-pharmacological interventions are scarcely implemented. Objective: To evaluate the effectiveness of the Describe, Investigate, Create, Evaluate (DICE) method™ to improve the care for NPS in AD

Pain intensity and psychological distress show different associations with interference and lack of life control : A clinical registry-based cohort study of >40,000 chronic pain patients from SQRP

Background: Both chronic pain and depressive and/or anxiety symptoms are associated with negative impacts on daily living, including interference and lack of life control. However, little is known about how pain and psychological distress affect these impacts. Aim: The first aim was to assess how pain intensity, psychological distress, and social support interact with interference and lack of life

The Historical Gender Gap Index: A Longitudinal and Spatial Assessment of Sweden, 1870-1990

This paper investigates the evolution of gender equality in Sweden during a phase characterized by industrialization, urbanization, and demographic transition. To this end, we build a database with quantitative indicators to construct a spatial Historical Gender Gap Index. We find that after a period of stagnation, Sweden made significant progress in closing the gender gap from the 1940s onward to

Circumferential Measurements to Calculate Lower Limb Volume in Persons with Lymphedema : What Segment Length Is to Be Recommended?

Background: Circumferential measurements (CMs) every 4th cm are commonly used to assess lower limb volume (LLV), but fewer measurements would be less time-consuming. The aim of this study was therefore to establish the agreement between LLV measurements derived from CM every 4th cm (V4), 8th cm (V8), and 12th cm (V12), and to evaluate the intrarater test-retest reliability for each of the three me

Integration of Specialized Palliative Care with Oncological Treatment in Patients with Advanced Pancreatic Cancer

INTRODUCTION: The incidence of pancreatic cancer is around 5 in 100,000, and the 5-year survival is poor. Pancreatic cancer patients have a high disease-specific burden of symptoms, and palliative chemotherapy has varying side effects. The American Society of Clinical Oncology (ASCO) suggests integrating specialized palliative care (SPC) with standard oncological treatment for pancreatic cancer pa

Constructive Dissonance in the Cloud: Adaptive Out-of-Phase Scheduling for Periodic Tasks

In the realm of cloud computing, the prevalence of intra-phase congestion due to concurrent periodic requests from a multitude of clients frequently results in heightened resource consumption, elongated queuing times, and prolonged response durations. To tackle these challenges, this paper presents a groundbreaking 'Adaptive Out-of-Phase Scheduling' technique, utilizing a server-side PID controlle

Numerical Investigation of Engine Performance and Emission Characteristics of an Ammonia/Hydrogen/n-Heptane Engine Under RCCI Operating Conditions

This paper examines the potential of using ammonia (NH 3) as a primary fuel in heavy-duty engines for decarbonization, with some challenges yet to be addressed. It presents a numerical study of a Reactivity Controlled Compression Ignition engine, where pilot diesel is used to ignite the premixed ammonia/air mixture. The numerical model and combustion mechanism are validated against engine experime

Light-Induced Metastable Hidden Skyrmion Phase in the Mott Insulator Cu2OSeO3

The discovery of a novel long-lived metastable skyrmion phase in the multiferroic insulator Cu2OSeO3 visualized with Lorentz transmission electron microscopy for magnetic fields below the equilibrium skyrmion pocket is reported. This phase can be accessed by exciting the sample non-adiabatically with near-infrared femtosecond laser pulses and cannot be reached by any conventional field-cooling pro

Secondary ice production : An empirical formulation and organization of mechanisms among simulated cloud-types

Clouds are essential elements within Earth's atmosphere, posing a challenge for cloud-resolving models in understanding the creation of new cloud ice particles from existing ice and liquid phases. Such ice initiation determines cloud microphysical and radiative properties, influencing cloud phase, precipitation and cloud extent/properties. To address this challenge effectively, it proves beneficia