Patch testing with hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) - a multicentre study of the Swedish Contact Dermatitis Research Group
Background: In 2014, the fragrance hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) was excluded from the Swedish baseline series. Objectives: To study (i) whether fragrance mix (FM) II with 5% HICC detects more positive reactions than FM II with 2.5% HICC, and (ii) the reproducibility of patch testing with HICC. Methods: Two thousand one hundred and eighteen dermatitis patients at five Swedish