Development of Gene Therapy for Malignant Osteopetrosis
Richter Group Our Research Osteoclasts and osteoblasts are two important mediators in the tightly regulated process of bone remodelling. The bone-forming osteoblasts are of mesenchymal origin while the multinucleate osteoclasts, which are responsible for bone resorption, are derived from hematopoietic stem cells (HSCs). An imbalance between the production and destruction of bone can lead to either
https://www.stemcellcenter.lu.se/research-groups/richter - 2025-08-09