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Vascular dysfunction is a hallmark of systemic inflammatory responses such as bacterial sepsis. The luminal surface of the blood vessels is coated with a dense layer of glycans and proteoglycans, collectively known as the glycocalyx. Surface associated glycoproteins of endothelial origin, or derived from pericytes, intravascular leukocytes, and plasma, are other important components of the glycoca
Most pathobionts of the respiratory tract form biofilms during asymptomatic colonization to survive and persist in this niche. Environmental changes of the host niche, often resulting from infection with respiratory viruses, changes of the microbiota composition, or other host assaults, can result in biofilm dispersion and spread of bacteria to other host niches, resulting in infections, such as o
Scientists have deemed existing protected areas in European forests insufficient to halt and reverse biodiversity loss resulting from ongoing intensification of management. In Sweden, protected areas are therefore complemented with the so-called areas of high conservation value (AHCVs), that is, landscapes encompassing both protected and assumed biodiversity-valuable areas as well as surrounding l
BACKGROUND: Cerebral palsy (CP) is an umbrella term where an injury to the immature brain affects muscle tone and motor control, posture, and at times, the ability to walk and stand. Orthoses can be used to improve or maintain function. Ankle-foot orthoses (AFOs) are the most frequently used orthoses in children with CP. However, how commonly AFOs are used by children and adolescents with CP is st
This paper proposes a ‘tool for thinking with’: that we can describe the interaction between people and computers, and especially people and developer tools, as a form of conversation. We outline this perspective, construct a work in progress analytical frame, and use it to talk about a couple of different examples and draw implications for future work.
Disinformation re-emerged in the 21st century as a public concern and professional challenge for actors seeking to navigate the new political and information landscape. This has led to a growing discussion among researchers on how disinformation relates to PD theory and practice. This chapter argues that disinformation comes with a set of opportunities for PD that open new perspectives to unresolv
Chemically sensitive diagnostics are indispensable to unravel reactive processes in combustion and beyond, to understand their development in time and space and to monitor the reaction progress under the conditions of interest. A multitude of techniques is available that may provide species composition together with other process-controlling variables as a function of the reaction environment. Ana
The actualization of action possibilities (i.e., affordances) can often be accomplished in numerous ways. For instance, an individual could walk over to a rubbish bin to drop an item in or throw the piece of rubbish into the bin from some distance away. The aim of the current study was to investigate the action dynamics that emerge from such under-constrained task or action spaces using an object
The design of Sensory Substitution Devices (SSDs) often relies on the belief that the information supplied by the devices should allow the construction of spatial mental representations on the basis of which routes are planned. This study, in contrast, illustrates that navigation using an SSD can be conceived as an on-line, dynamic process, without the need for establishing a predefined plan or mo
While eighteenth-century print media in essence rested on the same technical apparatus as previous centuries – letterpress printing, woodcuts, and intaglio prints – the growth in quantity created a media revolution. The effect was a qualitative shift in terms of literacy, growth of newspapers, the spread of images, and distribution of knowledge, but also of misinformation and propaganda. In this v
Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis, resulted in classical epidemics and remain a global health problem. While outbreaks of puerperal sepsis have been ascribed to Streptococcus pyogenes, little is known about disease mechanisms. Here, we show that the bacterial R28 protein, which is epidemiologically associated with outbreaks of puerperal seps
Development of integrated, continuous biomanufacturing (ICB) processes brings along the challenge of streamlining the acquisition of data that can be used for process monitoring, product quality testing and process control. Manually performing sample acquisition, preparation, and analysis during process and product development on ICB platforms requires time and labor that diverts attention from th
The chapter studies relational peace at the negotiation table in the Philippine peace talks between the government and the Communist Party of the Philippines (CPP), and discusses this in relation to the larger web of relations shaping the peace talks. Based on direct observations from the third round of talks in 2017 and interviews with representatives of the two parties, the chapter analyzes the
Research shows that young people within ethnic minorities are subjected to police control more often than others, which seems to have a damaging effect on their trust in the police as well as on their wider sense of belonging. What is less often researched is how these young people deal with being over-policed. This article explores narratives of over-policing from those targeted by the police in Research shows that young people within ethnic minorities are subjected to police control more often than others, which seems to have a damaging effect on their trust in the police as well as on their wider sense of belonging. What is less often researched is how these young people deal with being over-policed. This article explores narratives of over-policing from those targeted by the police in
Uppsatsens huvudsyfte har varit att utröna om det fanns några skillnader ipolitisk kultur mellan de socknar som låg i Blekinge och de socknar som låg ide gammalsvenska delarna av Sverige. Frågan tar sin utgångspunkt i K.H. Johanssons klassiska avhandling om de svenska sockenstämmorna. Han drar slutsatsen att stämmorna var demokratiska institutioner, där alla församlingens medlemmar fick delta och The main aim of this study was to determine whether there were any differences in political culture between the parishes of Blekinge and parishes in the older parts of Sweden. The question has its point of departure in K. H. Johansson's now classic dissertation on the Swedish parish assernbles. He reaches the conclusion that the assemblies were democratic institutions, in which all the members of
Health and demographic surveillance systems (HDSSs) provide a foundation for characterizing and defining priorities and strategies for improving population health. The Child Health and Mortality Prevention Surveillance (CHAMPS) project aims to inform policy to prevent child deaths through generating causes of death from surveillance data combined with innovative diagnostic and laboratory methods.
