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We aimed to identify genetic variants associated with cortical bone thickness (CBT) and bone mineral density (BMD) by performing two separate genome-wide association study (GWAS) meta-analyses for CBT in 3 cohorts comprising 5,878 European subjects and for BMD in 5 cohorts comprising 5,672 individuals. We then assessed selected single-nucleotide polymorphisms (SNPs) for osteoporotic fracture in 2,
In a recent article, David (Tarski’s convention T and the concept of truth, pp. 133–156, 2008) distinguishes between two interpretations of Tarski’s work on truth. The standard interpretation has it that Tarski gave us a definition of truth in-L within the meta-language; the non-standard interpretation, that Tarski did not give us a definition of true sentence in L, but rather a definition of trut
An efficient integral equation based solver is constructed for the electrostatic problem on domains with cuboidal inclusions. It can be used to compute the polarizability of a dielectric cube in a dielectric background medium at virtually every permittivity ratio for which it exists. For example, polarizabilities accurate to between five and ten digits are obtained (as complex limits) for negative
Patients with acute dyspnea are a large heterogeneous patient group where initial management is important for outcome.
Climate data from Empakaai Crater in northern Tanzania, covering the last 1200 years, are related to the establishment, development and decline of the ancient irrigation system at Engaruka. New dates for the system are linked to reconstructed climatic variations and historical data on long-distance and regional trade and migration patterns. A shift from a comparatively humid climate to drier condi
Background and purpose As much as one-third of all total hip arthroplasties in patients younger than 60 years may be a consequence of developmental dysplasia of the hip (DDH). Screening and early treatment of neonatal instability of the hip (NIH) reduces the incidence of DDH. We examined the radiographic outcome at 1 year in children undergoing early treatment for NIH. Subjects and methods All chi
This review of the history of ultraviolet photobiology focuses on the effects of UV-B (280-315 nm) radiation on terrestrial plants. It describes the early history of ultraviolet photobiology, the discovery of DNA as a major ultraviolet target and the discovery of photoreactivation and photolyases, and the later identification of Photosystem II as another important target for damage to plants by UV
This article explores the quest among contemporary pentecostal migrants from mainland Tanzania in Zanzibar to become “saved” Christians. The analysis of a set of techniques and processes applied in developing and keeping faith reveals high levels of suspicion and doubt connected to the perceived presence of evil in the Zanzibari environment, which, in turn, is linked to a fear of losing salvation.
Obesity hypoventilation syndrome (OHS) is often diagnosed late. The aim of this study was to analyse gender differences at initiation of long-term mechanical ventilation (LTMV) in patients with (OHS), to analyse gender differences in treatment effect and to study how the prescription of LTMV due to OHS has changed over time.
In LTE base-stations, RoHC is a processingintensive algorithm that may limit the system from serving a large number of users when it is used to compress the VoIP packets of mobile traffic. In this paper, a hardware-software and a full-hardware solution are proposed to accelerate the RoHC compression algorithm in LTE base-stations and enhance the system throughput and capacity. Results for both sol
Human α-lactalbumin made lethal to tumor cells (HAMLET) and equine lysozyme with oleic acid (ELOA) are complexes consisting of protein and fatty acid that exhibit cytotoxic activities, drastically differing from the activity of their respective proteinaceous compounds. Since the discovery of HAMLET in the 1990s, a wealth of information has been accumulated, illuminating the structural, functional
Various biological tissues are designed to optimally support external loads for complex geometries and mechanobiological structures. This results in complex microstructures of such materials. The design of, for instance, (healthy) arteries, which are in the focus of this work, is characterised by a residually stressed fibre-reinforced multi-layered composite with highly non-linear elastic response
In Meru, Tanzania, changing land/labour ratios have, for over a century, been the main driving force in a farm intensification process. The construction and expansion of irrigation systems, increased use of farm inputs and transfer from low- to high-value agricultural crops have enabled smallholders to improve their land productivity. Technological change has been accompanied by institutional chan
BACKGROUND Genome-wide association studies have identified several genetic loci associated with variation in resting heart rate in European and Asian populations. No study has evaluated genetic variants associated with heart rate in African Americans. OBJECTIVE To identify novel genetic variants associated with resting heart rate in African Americans. METHODS Ten cohort studies participating in th
Benchmarking has received much attention in local government. However, since benchmarking within a networking environment is quite a recent phenomenon, there is a need for better understanding of the impact of these networks on local government. This article describes municipal benchmarking networks and analyzes and categorizes variations in action and performance among municipalities participatin
The energy use for maintaining comfortable indoor temperatures are to a certain extent dependent on the thermal storage capacity of materials in contact with the indoor air. This article describes a conceptual model for investigating the effects of increasing the thermal storage capacity of building materials. A building is modeled as an exterior wall, an indoor air volume and a thermally heavy in
The ash cloud of the Eyjafjallajokull (also referred to as: Eyjafjalla (e.g. Schumann et al., 2011), Eyjafjoll or Eyjafjoll (e.g. Ansmann et al., 2010)) volcano on Iceland caused closure of large parts of European airspace in April and May 2010. For the validation and improvement of the European volcanic ash forecast models several research flights were performed. Also the CARIBIC (Civil Aircraft
Temperature management for patients comatose after cardiac arrest has been an integral component of postcardiac arrest care for the last decade. In this review, we present recent findings and discuss implications for future trials.
