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Common health issues have been less examined in studies of early language development, particularly in relation to the child’s sex. Respiratory tract infections, often complicated by acute otitis media, are common in children during the first years of life, when early vocabulary development takes place. The present study, conducted in Finland, aimed to investigate whether possible associations bet
Objective: To validate the Voice Handicap Index-Throat (VHI-T) in Brazilian Portuguese and compare the three formats: VHI-T-Br, VHI-T used in combination with the Voice Handicap Index (VHI), and VHI-T used in combination with the reduced version of the Voice Handicap Index (VHI-10) Methods: This cross-sectional study was approved by the Research Ethics Committee. Recruitment and data collection we
Several studies have shown the benefits for teachers and students in using Sound Field Amplification Systems (SFA). This study evaluates the effects of SFAs on reducing vocal strain in daycare staff and enhancing children's concentration in noisy environments. The study's novelty lies in exploring SFA use in the complex environments of daycare centers. Utilizing a mixed-methods approach, structure
Purpose This study assesses changes in speech production caused by altered auditory feedback provided through two bone conduction devices. The first device uses sidetone amplification through bone conduction headphones and the second device, called Forbrain®, applies a two-band equalizer filter to the voice signal and provides this altered auditory signal through bone conduction headphones. Togeth
Objective: This study aims to translate and cross-culturally adapt the throat scale of the Voice Handicap Index to the Brazilian Portuguese language.uracy. Material and Methods: This was performed in five phases translation, synthesis, back translation, review, and pretest. Fifty subjects participated in the pretest, of which 22 participants had chronic cough, 13 had laryngopharyngeal reflux, and
The incorporation of electron-withdrawing B←N coordination units has emerged as an effective strategy to enhance n-type charge transport in conjugated polymers. However, the orientation of these units, whether perpendicular or parallel to the polymer backbone, profoundly influences effective conjugation, molecular packing, and ultimately charge transport properties. To address this structure-prope
Imaging technologies are very crucial in today's society, with critical importance in three major domains: security and risk detection, medical diagnosis, and industrial quality control. Imaging techniques enable the visualization, sensing, and detection of signals across the entire electromagnetic spectrum. Starting from early digital radiographs to complex hyperspectral or low-light techniques,
BACKGROUND: Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus bacteremia is unclear.METHODS: In an ongoing international Bayesian adaptive platform trial, we conducted an open-label, randomized comparison of cefazolin with an antistaphylococcal penicill
BACKGROUND: Previously considered rare, penicillin-susceptible Staphylococcus aureus (PSSA) bacteraemia has re-emerged worldwide. Although benzylpenicillin might offer advantages in terms of pharmacokinetic and adverse effect profiles, anti-staphylococcal penicillins are recommended for serious infections because of concern over undetected penicillin resistance. We aimed to compare benzylpenicilli
Purpose – This article aims to examine how the agile approach interrelates with project complexity in product development. Design/methodology/approach – The study adopts a case study approach, using multiple dimensions of project complexity as an analytical framework to examine two complementary product development projects that involved the agile approach. Findings – The findings reveal that the
Background: Polygenic risk scores (PRSs) strongly discriminate for prostate cancer risk at the population level. The role of these genetic scores in determining prostate cancer survival is unclear, potentially due to methodological issues. Methods: We included 19,607 men from the Malmö Diet and Cancer Study (MDCS) and the Health Professionals Follow-up Study (HPFS) and analyzed 20-year incidence a
Background: Studies suggest increased phosphate removal when using hemodiafiltration (HDF) compared with hemodialysis (HD), but a complete analytic comparison has not been reported. Methods: We analyzed data from a 6-month prospective, multicenter, cross-sectional study that enrolled patients treated with high-flux HD or HDF and in whom residual kidney phosphate clearances (KrPhos) were measured.
ABSTRACTBackground and Objective: Working from a harm reduction (HR) approach underscores that addiction care professionals (ACPs) serve people with substance use disorder in a non-judgmental environment, encouraging people to seek intervention without abstinence as the ultimate goal. This study aims toexplore and compare the attitudes toward the acceptability of harm reduction among ACPs in SouthABSTRACTBackground and Objective: Working from a harm reduction (HR) approach underscores that addictioncare professionals (ACPs) serve people with substance use disorder in a non-judgmental environment,encouraging people to seek intervention without abstinence as the ultimate goal. This study aims toexplore and compare the attitudes toward the acceptability of harm reduction among ACPs in SouthAf
Carbon monoxide (CO) poisoning is a leading cause of environmental poisoning in the United States and can impair cellular metabolism through both hypoxia and direct mitochondrial toxicity, particularly via inhibition of cytochrome c oxidase (Complex IV, CIV). In this study, we performed a comprehensive assessment of the cerebral metabolic response to CO exposure in a swine model. Twenty-nine swine
Heavy-duty trucks, especially those used in urban areas, are responsible for a disproportionally large share of the external costs of the transportation sector. Policy instruments that target these trucks could thus be efficient measures to reduce negative impact from the traffic sector. This paper presents how heavy-duty trucks operated in Sweden’s two largest cities, Gothenburg and Stockholm, in
Childhood cancer aetiology is poorly understood and is considered to originate in utero and early postnatal life. In this study, we investigated perinatal characteristics as potential risk factors by performing a population-based case-control study, including 1340 cancer cases diagnosed < 19y and born between 1989–2021 in southern Sweden, and 13400 controls matched by sex, year, and municipality o
Rapporten analyserar finansieringen av den offentliga välfärden i Skåne inom ramen för ett decentraliserat system där kommuner och regioner har ett omfattande ansvar för många välfärdstjänster. Finansieringen baseras huvudsakligen på beskattning av förvärvsinkomster, vilket innebär att systemets stabilitet är nära kopplad till utvecklingen av arbetsmarknaden samt skattebasens storlek och fördelnin
Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an 82-year-old woman with recurrent hospital admissions initially spanning six months for diarrhea, weight loss, peripheral edema, and persistent hypoalbuminemia. Initi
Background – Air–liquid interface (ALI) cell culture systems have improved the study of host-pathogen interactions in respiratory infections. However, most ALI models lack immune components, limiting their ability to capture epithelial–immune crosstalk. To address this, we developed a dual-cell ALI model incorporating human peripheral blood monocyte-derived macrophages beneath differentiated airwa
