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Disentangling the Arcturus stream
Context. The Arcturus stream is an over-density of stars in velocity space and its origin has been much debated recently without any clear conclusion. The (classical) dissolved open cluster origin is essentially refuted; instead the discussions try to distinguish between an accretion, a resonant, or an external-perturbation origin for the stream. As kinematic structures are observational footprint
Exploring the conditions for forming cold gas giants through planetesimal accretion
The formation of cold gas giants similar to Jupiter and Saturn in orbit and mass is a great challenge for planetesimal-driven core accretion models because the core growth rates far from the star are low. Here we model the growth and migration of single protoplanets that accrete planetesimals and gas. We integrated the core growth rate using fits in the literature to N-body simulations, which prov
Automatic for the people : a rapidly evolving movement for the future of genotyping
The construction and navigation of riskscapes in public health advice and mothers’ accounts of weaning
This paper adds to critical studies of risk and mothering by illustrating and conceptualising how risk is constructed in public health advice and mothers’ accounts of weaning. Previous research points towards a gap between public health scientific definitions of risk and mothers’ contextual understandings and experience of handling complex and often conflicting risks linked to food and feeding. It
Changing diagnostic criteria for gestational diabetes in Sweden - A stepped wedge national cluster randomised controlled trial - The CDC4G study protocol
Background: The optimal criteria to diagnose gestational diabetes mellitus (GDM) remain contested. The Swedish National Board of Health introduced the 2013 WHO criteria in 2015 as a recommendation for initiation of treatment for hyperglycaemia during pregnancy. With variation in GDM screening and diagnostic practice across the country, it was agreed that the shift to new guidelines should be in a
The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
The incidence of treatment-related neuroendocrine prostate cancer (t-NEPC) is rising as more potent drugs targeting the androgen signaling axis are clinically implemented. Neuroendocrine transdifferentiation (NEtD), an putative initial step in t-NEPC development, is induced by androgen-deprivation therapy (ADT) or anti-androgens, and by activation of the β2-adrenergic receptor (ADRB2) in prostate
A noninteracting low-mass black hole–giant star binary system
Black hole binary systems with companion stars are typically found via their x-ray emission, generated by interaction and accretion. Noninteracting binaries are expected to be plentiful in the Galaxy but must be observed using other methods. We combine radial velocity and photometric variability data to show that the bright, rapidly rotating giant star 2MASS J05215658+4359220 is in a binary system
Assembly and analysis of the genome sequence of the yeast Brettanomyces naardenensis CBS 7540
Brettanomyces naardenensis is a spoilage yeast with potential for biotechnological applications for production of innovative beverages with low alcohol content and high attenuation degree. Here, we present the first annotated genome of B. naardenensis CBS 7540. The genome of B. naardenensis CBS 7540 was assembled into 76 contigs, totaling 11,283,072 nucleotides. In total, 5168 protein-coding seque
Green Path Development and Change Agency in Nordic Regions: A Collage from the Observations of the GONST Project
Development and application of a questionnaire to self-rate physical work demands for ground combat soldiers
PurposeThe aim of the present study was to identify the most physically demanding work tasks for Swedish ground combat soldiers through the development and application of a questionnaire survey. This is the first in a series of studies aiming to describe the development process and validation of physical selection standards in the Swedish armed forces.MethodsBased on procedural documentation, comb
SELF-RATED PHYSICAL WORK DEMANDS FOR GROUND COMBAT SOLDIERS
Modelling gas-liquid mass transfer in wastewater treatment : when current knowledge needs to encounter engineering practice and vice versa
Gas-liquid mass transfer in wastewater treatment processes has received considerable attention over the last decades from both academia and industry. Indeed, improvements in modelling gas-liquid mass transfer can bring huge benefits in terms of reaction rates, plant energy expenditure, acid-base equilibria and greenhouse gas emissions. Despite these efforts, there is still no universally valid cor
The Role of Hypothalamic Pathology for Non-Motor Features of Huntington's Disease
Huntington's disease (HD) is a fatal genetic neurodegenerative disorder. It has mainly been considered a movement disorder with cognitive symptoms and these features have been associated with pathology of the striatum and cerebral cortex. Importantly, individuals with the mutant huntingtin gene suffer from a spectrum of non-motor features often decades before the motor disorder manifests. These sy
A novel conserved family of Macro-like domains—putative new players in ADP-ribosylation signaling
The presence of many completely uncharacterized proteins, even in well-studied organisms such as humans, seriously hampers a full understanding of the functioning of living cells. One such example is the human protein C12ORF4, which belongs to the DUF2362 family, present in many eukaryotic lineages and conserved in metazoans. The only functional information available on C12ORF4 (Chromosome 12 Open
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Denmark: Anti-urbanism and segregation
Barcelona: Housing crisis and urban activism
Co-housing is an emerging housing form in Spain, where many pioneering initiatives are found in Catalonia and the Barcelona area. Using the La Borda project as a recurring illustration, but also drawing on other examples and developments, the chapter seeks to contextualize this nascent but noticeable interest in co-housing in and around Barcelona. Starting at the scale of the crisis-ridden Spanish
Urban activism and co-housing
This chapter looks at the interrelations and dynamics between urban activism and the politics of co-housing. Drawing on empirical material from Hamburg and Barcelona, it explores the socio-political context of co-housing in the interplay of bottom-up organizing and top-down governance. With particular attention to squatting and related questions of post-autonomous urban activism, this investigatio
Co-housing, sustainable urban development and governance : An introduction
Co-housing is often lauded as an alternative housing form offering a more socially, ecologically and economically sustainable way of living. This book takes its departure in the need for a critical exploration of co-housing in the context of sustainable urban development, beyond the normative approach that often characterizes co-housing research. Based on a four-year research project involving in-