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INTRODUCTION: Since sleep disturbance is a modifiable risk factor for Alzheimer's disease (AD), we tested associations between sleep and AD pathology in cognitively unimpaired (CU) persons. METHODS: We included 223 participants from the PREVENT-AD cohort with self-reported measures of sleep, objective actigraphy measures of sleep, and positron emission tomography (PET) scans for AD pathology quant
I syfte att förstå queer världsskapande praktiker – skapandet av en värld som står i motsats till hegemonisk heteronormativitet – sammanställer denna avhandling ett rörigt och rörligt arkiv av autoetnografi, intervju och film och utvecklar en kulturell analys. Ett fokus på berättande praktiker tillåter mig att spåra hur berättelser formas och förmedlas inom bredare kulturella kontexter genom situeAiming to understand practices of queer worldmaking – a world counter to hegemonic heteronormativity – my thesis brings together living and moving archives of autoethnography, interviews, and films to develop a cultural analysis. A focus on storytelling allows me to trace how stories are shaped and communicated within broader cultural contexts through situated and everyday acts of telling stories.
Atopic dermatitis (AD) is a chronic skin disease associated with impaired quality of life. Evidence from Sweden on out-of-pocket expenses and productivity losses remains limited. This study assessed the burden of AD among adults in relation to health-related quality of life (HRQoL), work productivity, activity impairment, willingness to pay for symptom relief, economic outcomes, considering comorb
The article presents Fady Joudah’s Textu as an innovative combination of poetry (haiku) and communication technology (text messaging). The paper questions the traditional distinction between literature and other media, exploring how digital formats affect the understanding of “text” and the experience of reading. The authors of the article invoke intermedial theory (Lars Elleström, Beate Schirrmac
Background: First-line managers in healthcare operate in increasingly complex environments marked by high demands, rapid change, and limited resources. These conditions impact their health, leadership capacity, and the sustainability of their roles. While previous research has addressed various aspects of leadership in healthcare, there is a lack of studies focusing specifically on how first-line
Background: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) enables sensitive detection and staging of prostate cancer, yet its relationship with long-term survival remains unclear. This study aimed to assess whether total lesion volume (TLV) measured on [18F]PSMA-1007 PET/CT predicts overall survival (OS) in prostate cancer patients. Methods: A co
Amelogenin self-assembly is a critical step in enamel matrix organization, supporting the spatial confinement of transient ACP and orchestrating hydroxyapatite nucleation and ordered growth. Studies have demonstrated that amelogenin self-assembles into nanoribbons by forming an amyloid-like structure that matches the cross-β pattern observed in the developing enamel matrix. However, molecular dete
Air pollution is the world’s deadliest environmental risk factor. Yetthere is little effort to educate the public about personal exposureto pollutants such as particulate matter (PM). This paper presentsthe design and implementation of a portable sensor box (PSB) tocollect local, spatially highly resolved particulate matter data. Tocounteract common inaccuracies in mobile particulate matter mea-su
The European Commission defines the Green Transition as the transformation set out in the European Green Deal. Ensuring that this transition is just is both an ethical requirement and a practical condition for maintaining public support and policy effectiveness. This Perspective proposes a multidimensional framework for assessing justice in Green Transition policies, encompassing distributional, p
The evacuation of hospitals in the event of fires and similar emergencies can be a difficult endeavor. Patients usually require assistance, with a considerable number of them being unable to evacuate by themselves due to medical conditions or due to the treatment they are receiving. Assistance is to be provided by the healthcare staff in the affected ward, which means that their level of preparedn
Vad kännetecknar egentligen kapitalismen, hur fungerar den och varför är den så seglivad? Harvardhistorikern Sven Beckert reder ut begreppen på mer än 1 300 sidor.
The mountain front recharge (MFR) process significantly influences the movement of water and dissolved organic carbon (DOC) in alpine catchments. However, no existing watershed models can adequately simulate this process, hindering accurate quantification of streamflow and DOC dynamics. To address this gap, this study explicitly incorporated the MFR process into a watershed-scale integrated water–
The climate change in northern Europe is not only leading to more extreme weather events but also causing long dry summers. This affects the moisture content of the ground and the vegetation. Causing an increased number of wildfires within Germany posing a risk to the environment, society, and firefighters. Surface fire spread in wildfires can be influenced by several environmental conditions and
Ni1+δSn (δ = 0.2, 0.4) and Ni1+δ(In/Sb) (δ = 0.1–0.5) (NiAs/Ni2In type) were synthesized, and their crystal structures were studied in this report. In Ni1+δ(In/Sb), the excess nickel atoms (δ = 0.1–0.5) occupy the vacant trigonal bipyramidal interstitial sites in the NiAs-type structural arrangement, leading to the evolution of a fully disordered to ordered superstructure through a series of incom
Aims Social anxiety disorder (SAD) is one of the most common anxiety disorders and is associated with significant impairment and societal costs. The association between SAD and mortality remains poorly understood, partly because in epidemiological research it is rarely studied independently from other anxiety disorders. In this population-based matched cohort and sibling control study, we estimate
Background: Increasing healthcare demands and a growing nursing shortage contribute to high workloads, psychosocial strain, and risks to care quality. Organisational conditions, job demands, and resources strongly influence nurses’ well-being, retention, and performance. Aim: To examine how nurses balance organisational demands and opportunities, and how these factors relate to work environment, w
Almost no seminar, book, or YouTube tutorial on successful public speaking is without the established and traditional “cork exercise.” It is supposed to enhance speakers’ rhythm and intelligibility, for which there is, however, no scientific evidence so far. Our experiment addresses this gap. Twenty speakers performed a presentation task three times: (1) before a cork exercise intervention, (2) im
A string of speech is a string of syllables, a series of varying amounts of jaw openings/closings. Neutralizing the vowel-intrinsic jaw opening indicates a pattern of jaw opening matching the utterance syllable prominence patterns. The hypothesis is that the jaw-opening patterns ensue from the metrical hierarchy of the language, such that for languages such as English, we see exponentially increas
Purpose: The purpose of this in-depth interview study was to explore how parents of children with sensorineural hearing loss (SNHL) experienced genetic testing and whether they experienced risks and benefits. Background: Most children with SNHL have a genetic etiology, which can be identified through genetic sequencing. A genetic test does not influence treatment, and whether patients and parents
This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of infection. We further examine the system under a threshold constraint on the infection level. Based on this analysis, we formulate an optimal control problem to keep
