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Acer campestre L. is a rarely silviculturally managed and poorly investigated European tree species which forms seminatural populations and can thus be considered as a model tree for studying post glacial colonisation and phylogeography. Herein, we studied the genetic structure of Acer campestre L. in order to investigate population and genetic diversity clines over the distribution range and for

Aims: To develop and validate sex-specific risk prediction models based on easily obtainable clinical data for predicting 5-year risk of type 2 diabetes (T2D) among individuals with impaired fasting glucose (IFG), and generate practical tools for public use. Methods: The data used for model training and internal validation came from a large prospective cohort (N = 18,384). Two independent cohorts

OBJECTIVES: The aim of this study was to compare readmissions and death between sepsis and non-sepsis hospitalisations the first year after discharge, and to investigate what diagnoses patients with sepsis present with at readmission. The aim was also to evaluate to what degree patients hospitalised for sepsis seek medical attention prior to hospitalisation. DESIGN: Retrospective case-control stud

The long theorized two-dimensional allotrope of SiC has remained elusive amid the exploration of graphenelike honeycomb structured monolayers. It is anticipated to possess a large direct band gap (2.5 eV), ambient stability, and chemical versatility. While sp2 bonding between silicon and carbon is energetically favorable, only disordered nanoflakes have been reported to date. Here we demonstrate l

I propose that the evolution of teaching has been central in extending manipulative intentions. Demonstrating may be the evolutionarily first form of expression that is productive, ostensive, and involves informative intention. Demonstration also involves theory of mind. Then pantomime goes a step further and involves a communicative intention. Pantomime can thereby function as displaced communica

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To evaluate the benefits and harms of stem cell-based interventions for the treatment of stroke in newborn infants compared to control (placebo or no treatment) or stem-cell based interventions of a different type or source.

Recent quasi-two-dimensional (quasi-2D) systems with judicious exploitation of the atomic monolayer or few-layer architecture exhibit unprecedented physical properties that challenge the conventional wisdom on condensed matter physics. Here we show that the infinite layer SrCuO2 (SCO), a topical cuprate Mott insulator in bulk form, can manifest an unexpected metallic state in the quasi-2D limit wh

Ageism is a social problem that has harmful effects on the wellbeing of older people and needs to be tackled. It is pervasive and evident in the media (e.g., films, television, print and social media). Despite the fact that non-individual actors have adopted social media on a large scale in contemporary society, the social media representation of older people generated by those actors has remained

The ongoing digitalisation of societies, exacerbated by the COVID-19 pandemic, has led to increased efforts to ensure the digital inclusion of older adults. Digital inclusion strategies throughout the COVID-19 pandemic predominantly focused on increasing access and basic digital literacy of Information and Communication Technologies (ICTs) for all members of society. Older adults, who are more lik

The Western Pacific Region is experiencing rapid population ageing, which has implications for almost all areas of society. Countries will need to prepare for population ageing by investing in health and optimizing living environments. This requires a whole-of-society approach to healthy ageing. Countries in the Western Pacific Region have been making significant progress in healthy ageing. Since

BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in

Apart from classical orthostatic hypotension, the gravitational force may strongly contribute to other forms of orthostatic intolerance, delayed and postprandial OH, postural orthostatic tachycardia syndrome (POTS), and reflex syncope. In delayed OH, the significant blood pressure drop occurs first after 3-min period of orthostasis, whereas in postprandial OH, the symptoms appear first approximate

Both the European Union (EU) Directive implementing the OECD’s Pillar Two and the proposal for a debt-equity bias reduction allowance (DEBRA) feature rules that target and limit interest deduction as the need for these still exists. However, in case C-484/19 Lexel from 2021, the Court of Justice of the European Union (CJEU) struck down the Swedish targeted interest deduction legislation of 2013 ap

This concluding article assesses the past decade of international scholarship on the European Union (EU) and normative power as represented by the contributions to the special issue. It argues that the normative power approach (NPA) makes it possible to explain, understand and judge the EU in global politics by rethinking the nature of power and actorness in a globalizing, multilateralizing and mu

"You're an out, a small out, and you're new. We don't want to hear from you."(Nicolas Sarkozy, in Barker and Parker, 2011)Holding the rotating Presidency of the Council of Ministers of the European Union (EU) is a challenging task for any Member State, but in the context of the global financial and eurozone crisis, the perceived decline of EU influence in the world and the growing resentment of EU

Circular water management has the potential to close resource and material loops within and across value chains. In the water industry, circular municipal wastewater management through industrial urban symbiosis (IUS) is recognized as a solution to overcome water scarcity in urban environments. IUS involves collaboration between actors with different organizational backgrounds, which can lead to i

Hormone secretion from pancreatic islets is essential for glucose homeostasis and loss or dysfunction of islet cells is a hallmark of type 2 diabetes. Maf transcription factors are critical for establishing and maintaining adult endocrine cell function. However, during pancreas development, MafB is not only expressed in insulin- and glucagon-producing cells, but also Neurog3+ endocrine progenitor