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Validity of registration of ICD codes and prescriptions in a research database in Swedish primary care: a cross-sectional study in Skaraborg primary care database

Background: In recent years, several primary care databases recording information from computerized medical records have been established and used for quality assessment of medical care and research. However, to be useful for research purposes, the data generated routinely from every day practice require registration of high quality. In this study we aimed to investigate (i) the frequency and vali

Polymorphic drugs examined with neutron spectroscopy: Is making more stable forms really that simple?

Understanding polymorphism in pharmaceutical ingredients is a long-standing challenge in formulation science. A well-known example is paracetamol, C8H9NO2. The marketed stable form I crystallizes with corrugated molecular layers. In contrast, form II, which is thermodynamically favorable at high pressures, has relatively planar layers that can slip over each other without difficulty, but is metast

Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974-2002

Background: Despite a decreasing incidence of peptic ulcer disease, most previous studies report a stabile incidence of ulcer complications. We wanted to investigate the incidence of peptic ulcer complications in Sweden before and after the introduction of the proton pump inhibitors (PPI) in 1988 and compare these data to the sales of non-steroid anti-inflammatory drugs ( NSAID) and acetylsalicyli

The status of essential elements and associations with milk yield and the occurrence of mastitis in organic and conventional dairy herds

There is a lack of detailed information on the impact of organic feeding regulation on the health and well-being of cows. This has become especially important since January 2008 when the EU required 100% organic ration for organic dairy herds. The aim of this investigation was to determine and compare the levels of essential elements in organic and conventional dairy herds, and to associate them w

Association between multi-dose drug dispensing and drug treatment changes

Purpose To compare drug treatment changes in older hip fracture patients with and without multi-dose drug dispensing (MDD) after discharge from hospital. Methods Hip fracture patients (aged 65 years or older) for whom the same prescribing procedure was used at discharge and at the 6-month follow-up were extracted from two patient cohorts consecutively recruited in 2008 (n=100) and 2009 (n=99), res

Rapidity gap cross sections measured with the ATLAS detector in pp collisions at root s=7 TeV

Pseudorapidity gap distributions in proton-proton collisions at root s = 7 TeV are studied using a minimum bias data sample with an integrated luminosity of 7.1 mu b(-1). Cross sections are measured differentially in terms of Delta eta(F), the larger of the pseudorapidity regions extending to the limits of the ATLAS sensitivity, at eta = +/- 4.9, in which no final state particles are produced abov

Allergen-Specific Immunotherapy Alters the Frequency, as well as the FcR and CLR Expression Profiles of Human Dendritic Cell Subsets.

Allergen-specific immunotherapy (AIT) induces tolerance and shifts the Th2 response towards a regulatory T-cell profile. The underlying mechanisms are not fully understood, but dendritic cells (DC) play a vital role as key regulators of T-cell responses. DCs interact with allergens via Fc receptors (FcRs) and via certain C-type lectin receptors (CLRs), including CD209/DC-SIGN, CD206/MR and Dectin-

Plasma Folate, Related Genetic Variants, and Colorectal Cancer Risk in EPIC

Background: A potential dual role of folate in colorectal cancer (CRC) is currently subject to debate. We investigate the associations between plasma folate, several relevant folate-related polymorphisms, and CRC risk within the large European Prospective Investigation into Cancer and Nutrition cohort. Methods: In this nested case-control study, 1,367 incident CRC cases were matched to 2,325 contr

Helicobacter pylori : Is it Transmitted Through Faecal-oral or Oral-oral Route?

The association of Helicobacter pylori with gastroduodenal diseases is well established. The mode of transmission of the organism is still unclear, although the faecal-oral route has been proposed. H. pylori has been detected in gastric antrum, dental plaques, faeces and water. In the light of these studies we attempted to detect H. pylori in antral biopsies, dental plaques, and stool specimens of

Att föra det egna till torgs : berättande, stoff och samtid i Kerstin Strandbergs, Enel Melbergs och Eva Adolfssons debutromaner

Popular Abstract in Swedish I Immi Lundins avhandling Att föra det egna till torgs står 1960-, 1970- och 1980-talen i fokus. Tre kvinnliga författares debutromaner, en från varje decennium, undersöks och sätts i relation till de förändrade positionerna i den offentliga kvinno- och litteraturdebatten under trettioårsperioden. Frågan som avhandlingen söker svar på gäller romanernas samspel med tillkThe Swedish debate both on the role of literature and on the social position of women underwent rapid change during the thirty years from 1960 to 1990. In Bringing the Personal to Market: Narrative, Subject-Matter and Contemporary History in the First Novels of Kerstin Strandberg, Enel Melberg and Eva Adolfsson, the debut novels of three female authors’ are close-read from a thematic and narratolo

Composition and microarchitecture of human trabecular bone change with age and differ between anatomical locations

The microarchitecture of trabecular bone adapts to its mechanical loading environment according to Wolff's law and alters with age. Trabecular bone is a metabolically active tissue, thus, its molecular composition and microarchitecture may vary between anatomical locations as a result of the local mechanical loading environment. No comprehensive comparison of composition and microarchitecture of t

Room-Temperature Near-Infrared Photodetectors Based on Single Heterojunction Nanowires

Nanoscale near-infrared photodetectors are attractive for their potential applications in integrated optoelectronic devices. Here we report the synthesis of GaSb/GaInSb p-n heterojunction semiconductor nanowires for the first time through a controllable chemical vapor deposition (CVD) route. Based on these nanowires, room-temperature, high-performance, near-infrared photodetectors were constructed

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Med egna radio- och TV-program, tidningar och sändningar tillgängliga på Internet formar den somaliska gruppen i Minnesota bilden av sig själv. Programmen tas fram genom ideellt arbete och bygger broar mellan kulturer.

"Bäste biskop!" : korrespondensen mellan drottning Victoria och biskop Gottfrid Billing 1900–1924

This is a critical edition of the correspondence between Queen Victoria of Sweden (1862-1930) and the Bishop and High Preacher to the Court, Gottfrid Billing (1841-1925), together with a commentary situating this surprisingly straightforward correspondence in its political and theological context. Since the queen lived both in the public and the private sphere, she had a ‘mixed’ relation to her sp

Search for W ' -> t(b)over-bar in the lepton plus jets final state in proton-proton collisions at a centre-of-mass energy of root s=8 TeV with the ATLAS detector

A search for new charged massive gauge bosons, called W', is performed with the ATLAS detector at the LHC, in proton-proton collisions at a centre-of-mass energy of root s = 8 TeV, using a dataset corresponding to an integrated luminosity of 20.3 fb(-1). This analysis searches for W' bosons in the W' -> t (b) over tilde decay channel in final states with electrons or muons, using a multivariate me

Våldet och kärleken : Våldsutsatta kvinnors begripliggörande av sina erfarenheter

The purpose of the thesis is to study, through the narratives of women subjected to violence, how men’s violence against women in intimate relationships is accounted for, and how such accounts vary with the type of social relation and context she is in. The specific context in focus here is the legal system, with the police as the first link in the legal chain. The empirical material consists of