Background/Aims. Obesity is a well-established risk factor for the development of numerous chronic diseases. However, there is a small proportion of obese individuals that seem to escape these aforementioned conditions—Metabolically Healthy Obesity (MHO). Our aim was to do a metabolic and biomarker profiling of MHO individuals. Method. Associations between different biomarkers (proteomics, lipidom

The starting point of this paper is to document considerable cross-country variation in the “labor wedge”, a common measure of labor market frictions. Its variation is theoretically isomorphic to differences in a preference-for-leisure parameter. The paper proceeds to investigate what might explain the variation. It presents three separate empirical exercises supportive of the view that, to a subs

Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative human pathogen that causes infections mainly in the upper and lower respiratory tract. The bacterium is associated with bronchitis and exacerbations in patients suffering from chronic obstructive pulmonary disease and frequently causes acute otitis media in preschool children. We have previously demonstrated that the binding of C4b bindi

While Bayesian Optimization (BO) is a very popular method for optimizing expensive black-box functions, it fails to leverage the experience of domain experts. This causes BO to waste function evaluations on bad design choices (e.g., machine learning hyperparameters) that the expert already knows to work poorly. To address this issue, we introduce Bayesian Optimization with a Prior for the Optimum

Having access to realistic and empirically grounded passenger valuations of public transport trip components facilitate the undertaking of necessary trade-offs during planning of transport networks. Discrete choice estimation of path choice preferences is a practical way to obtain such preferences. This paper proposes a new take on the empirical foundation of path choice estimation based on reveal

We give three elementary proofs of a nice equality of definite integrals, recently proven by Ekhad, Zeilberger, and Zudilin. The equality arises in the theory of bivariate hypergeometric functions, and has connections with irrationality proofs in number theory. We furthermore provide a generalization together with an equally elementary proof and discuss some consequences.

In this paper, a novel multi-region Eulerian model is presented to study the conversion of thermally thick biomass particles. In the present model, the particle and the surrounding fluid are treated as two separate regions that are coupled through an interface. There are some benefits for using a multi-region approach, including a more realistic radiation modeling, flexibility to define the flow b

Begreppet grön demokrati har förts fram inom grön politisk teori som ett sätt att inkludera den naturliga världen i den politiska och på så vis komma förbi en föreställd mur som separerar människor och natur i moderniteten och ersätta den med en brygga mellan dem. Begreppet tänks också härbärgera kraften att omvandla samhället i hållbar riktning. I denna studie argumenteras att grön demokrati diskThe concept of green democracy has been advanced in green political theory as a way to include the natural world in the political and, by that, overcome an alleged wall, a fundamental disunity, separating humans and nature in modernity and substitute it with a unity of identity that would bridge the gap between them. It has also been vested with the coupled power to transform society in a sustaina

BACKGROUND: The COVID-19 pandemic has had a profound effect on the emotional well-being of expecting mothers. Sweden's unique strategy for managing COVID-19 involved no national lockdown. Emphasis was instead placed on limiting crowding and asking citizens to practice social distancing measures.AIM: To gain a deeper understanding of how women not infected by SARS-CoV-2 experienced pregnancy during

We analyze to what extent the contribution of banks to systemic risk depends on their centrality in financial networks. We find that centrality is an important determinant of systemic risk, but not primarily by its direct effect. Its main influence is to make other risk measures, such as probability of default, more important for highly connected banks. Neglecting the indirect effect of centrality

Given the gaps between EU ambitions regarding energy community development and the current reality of clean energy communities in Europe, we explore a research framework enabling viable multi- and interdisciplinary research into new clean energy communities. We offer a definition of new clean energy communities, discuss their potential for wider dissemination and identify four factors that contrib

In this work, we have synthesized polystyrene particles that carry short end-grafted polyethylene glycol (PEG) chains. We then added dissolved 100 kDa PEG polymers and monitored potential flocculation by confocal microscopy. Qualitative predictions, based on previous theoretical developments in this field (Xie, F.; et al. Soft Matter 2016, 12, 658), suggest a non-monotonic temperature response. Th

Five peptides previously suggested to possess polyproline II (PPII) structure have here been investigated by using atomistic molecular dynamics simulations to compare how well four different force fields known for simulating intrinsically disordered proteins relatively well (Amber ff99SB-disp, Amber ff99SB-ILDN, CHARM36IDPSFF, and CHARMM36m) can capture this secondary structure element. The result

Extensive research is being conducted on magnesium (Mg) alloys for bone implant manufacturing, due to their biocompatibility, biodegradability and mechanical properties. Gadolinium (Gd) is among the most promising alloying elements for property control in Mg alloy implants; however, its toxicity is controversial. Investigating Gd behavior during implant corrosion is thus of utmost importance. In t

Background. Glucose is emerging as a biomarker for early and safe rule-out of acute myocardial infarction in emergency department (ED) chest pain patients. We evaluated the diagnostic accuracy of dual testing with high sensitivity TnT (hs-cTnT) and glucose for prediction of major adverse cardiac events (MACE) within 30 days. Methods. This was a secondary analysis of a single-center prospective obs