Schumpeter, Dahmén, Schön, Freeman, and other evolutionary scholars have shown that economic transformation and technological change are necessary prerequisites for long-term economic growth. However, for the Swedish case the exact sectoral and regional anatomy of the technology shift taking place since 1978 has not yet been disentangled. In this thesis, a disaggregation of the national process is

BACKGROUND: Of all patients with low back pain, 85% are diagnosed as "non-specific lumbar pain". Lumbar instability has been described as one specific diagnosis which several authors have described as delayed muscular responses, impaired postural control as well as impaired muscular coordination among these patients. This has mostly been measured and evaluated in a laboratory setting. There are fe

Somliga kanske ser ”interkommunal samverkan” som ett desperat uttryck från svaga kommuner, kämpande för sitt liv. Så kan det vara i en del fall, men inte i alla. Det krävs nämligen kraft för att hjälpas åt. Att lämna över en del av sitt eget öde – och ta ansvar för andras – är ingen avkoppling. Att samverka kan med andra ord likaväl vara ett tecken på styrka och framgång som en signal om svaghet o

A huge quantity of gene and protein sequences have become available during the post-genomic era, and information about genetic variations, including amino acid substitutions and SNPs, is accumulating rapidly. To understand the effects of these changes, it is often essential to apply bioinformatics tools. Where there is a lack of homologous sequences or a three-dimensional structure, it becomes ess

Experimental oscillator strengths for 19 ultraviolet lines of Pd II have been derived from measurements of line intensities in calibrated Fourier transform spectra, combined with picosecond-pulse laser measurements of radiative lifetimes. Five of these 19 lines, in addition to other Pd nr lines, are present in Hubble Space Telescope/Goddard High-Resolution Spectrograph echelle spectra of the chemi

Cigarette smoking is a strong cardiovascular risk factor and endothelin (ET) receptors are related to coronary artery diseases. The present study established an in vivo secondhand smoke (SHS) exposure model and investigated the hypothesis that cigarette smoke induces ET receptor upregulation in rat coronary arteries and its possible underlying mechanisms.

Background: Despite considerable racial and geographical differences in human phenotypes and in the incidence of diseases that may be associated with sex steroid action, there are few data concerning variation in sex steroid levels among populations. We designed an international study to determine the degree to which geography and race influence sex steroid levels in older men. Methods: Using mass

In Swedish, as in other North Germanic languages, compounds are very common and a majority of the novel words in Swedish are compounds. This thesis aims at a presentation of compounding in Swedish and the problems involved in describing compounding, but mainly at an empirically founded description of children's creation and use of novel compounds and developing comprehension of compounds, especial

Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in fo

Bone metastasis is a leading cause of morbidity and mortality in prostate cancer (PCa). While cancer stem-like cells have been implicated as a cell of origin for PCa metastases, the pathways which enable metastatic development at distal sites remain largely unknown. In this study, we illuminate pathways relevant to bone metastasis in this disease. We observed that cyclin A1 (CCNA1) protein express

BACKGROUND: Suicide attempts have been shown to be less common in older age groups, with repeated attempts generally being more common in younger age groups and severe attempts in older age groups. Consistently, most studies have shown an increased suicide risk after attempts in older age. However, little is known about the predictive value of age on repeated and severe suicide attempts for accomp