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Intensive care unit burden is associated with increased mortality in critically ill COVID-19 patients

BACKGROUND: Traditional models to predict intensive care outcomes do not perform well in COVID-19. We undertook a comprehensive study of factors affecting mortality and functional outcome after severe COVID-19.METHODS: In this prospective multicentre cohort study, we enrolled laboratory-confirmed, critically ill COVID-19 patients at six ICUs in the Skåne Region, Sweden, between May 11, 2020, and M

The Institutionalization of Gender-Based Violence (GBV) and Migrant Women’s Access to Social Protection System in Advanced Welfare Societies.

This study critically engages with the knowledge produced in the field of gender-based violence (GBV) in the context of migration. The focus is specifically on empirical studies that look at women whose immigrant status is precarious, which means that their pathway to citizenship is uncertain and dependent on others. Some examples are migrant women students, asylum claimants and refused asylum cla

Managing the rules of recognition : how early career academics negotiate career scripts through identity work

Due to the changing landscapes of higher education, a large body of research has studied how scholars make sense of academic identities and careers. Yet, little is known about how academics actually ‘work’ on their identities to navigate normative demands and complex career structures. This paper explores how scholars negotiate career scripts trough identity work. Drawing upon 35 interviews with eDue to the changing landscapes of higher education, a large body of research has studied how scholars make sense of academic identities and careers. Yet, little is known about how academics actually ‘work’ on their identities to navigate normative demands and complex career structures. This paper explores how scholars negotiate career scripts trough identity work. Drawing upon 35 interviews with e

The foot drawing method : reliability of measuring foot length and outward rotation in children with clubfoot

Background: The Ponseti method is the gold standard for clubfoot treatment. However, relapse and residual gait deviations are common, and follow-up until 7 years of age is recommended. We evaluated the reliability of the foot drawing method, a new instrument for the follow-up of clubfoot. The method uses drawings of the foot in the neutral position and external rotation to measure foot length and

The true costs of cesarean delivery for patients in rural Rwanda : Accounting for post-discharge expenses in estimated health expenditures

Introduction: While it is recognized that there are costs associated with postoperative patient follow-up, risk assessments of catastrophic health expenditures (CHEs) due to surgery in sub-Saharan Africa rarely include expenses after discharge. We describe patient-level costs for cesarean section (c-section) and follow-up care up to postoperative day (POD) 30 and evaluate the contribution of follo

Speed of cooling after cardiac arrest in relation to the intervention effect : a sub-study from the TTM2-trial

Background: Targeted temperature management (TTM) is recommended following cardiac arrest; however, time to target temperature varies in clinical practice. We hypothesised the effects of a target temperature of 33 °C when compared to normothermia would differ based on average time to hypothermia and those patients achieving hypothermia fastest would have more favorable outcomes. Methods: In this p

MRI-only radiotherapy from an economic perspective : Can new techniques in prostate cancer treatment be cost saving?

BACKGROUND AND PURPOSE: The aim of this study was to analyze a magnetic resonance imaging (MRI)-only radiotherapy workflow from an economic perspective in terms of reduced time, costs and systematic uncertainties.MATERIAL/METHODS: A documented Swedish clinical implementation of MRI-only radiotherapy was used as template for cost assessments compared to a combined computed tomography (CT)/MRI workf

Vile Vapours : Addiction and the Blood Pact in The Witch of Edmonton

The Witch of Edmonton has frequently been read as a play which exposes the social problems that led to witchcraft accusations in early modern society. This article examines another aspect of the play which has not yet been adequately discussed by literary scholars: the role of physiology, and especially the role of human blood, in the play’s representation of witchcraft and the devil’s manipulatio

Comparative Toxicity of Heavy Metals Cd, Pb, and Zn to Three Acrocarpous Moss Species using Chlorophyll Contents

Mosses have often been used for biomonitoring because of their diversity of habitats, structural simplicity, and rapid multiplication rate. This research aimed to study the tolerance of heavy metal in 3 species of terricolous mosses i.e., Barbula consanguinea, Hyophila apiculata, and H. involuta. The gametophores of mosses were immersed at 4 concentrations of each of the heavy metals Cd, Pb, and Z

Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Previous brain-autopsy findings suggest that the myelin levels—which differ substantially between white matter tracts in the brain—are a key modulating factor of re

Agile development of polymer power transmission systems for e-mobility : a novel methodology based on an e-bike drive case study

The market for electric bicycles has grown extremely and developed rapidly in recent years. To enter such a market with a new product, the development process has to be fast, and throughout the process, feedback from future potential customer(s) should be sought in order to achieve the best possible market acceptance. The article presents the design process of a pedelec e-bike central drive system

Gait parameters when walking with or without rollator on different surface characteristics : a pilot study among healthy individuals

Objectives: Gait parameters can measure risks of falling and mortality and identify early stages of frailty. The use of walking aid changes gait parameters. The aim of this study was to describe differences in gait parameters among healthy adults when walking on different surfaces and under different conditions, with and without a rollator. Results: Ten healthy participants walked first without an

Lipidomes of Icelandic bryophytes and screening of high contents of polyunsaturated fatty acids by using lipidomics approach

Bryophytes (mosses, liverworts, and hornworts) have interested researchers because of their high chemical diversity and their potential uses in pharmaceutical, food, and cosmetic industries. Specifically, long-chain polyunsaturated fatty acids (l-PUFA) such as arachidonic acid (AA) and eicosapentaenoic acid (EPA) are commonly found in bryophytes, but not in vascular plants. Bryophytes accumulate P

Comparative effectiveness research on proximal femoral nail versus dynamic hip screw in patients with trochanteric fractures : a systematic review and meta-analysis of randomized trials

Background: The treatments for trochanteric fractures try to regain early mobility and limit morbidity and risk of reoperations. The most currently used dynamic hip screw (DHS) and the proximal femoral nail (PFN) are both with pros and cons. We aimed to assess the comparative effectiveness of these interventions for trochanteric fractures by evaluating the surgical performance and postoperative ou

Healthcare seeking among Swedish patients in opioid substitution treatment – a mixed methods study on barriers and facilitators

Background: Patients in opioid substitution treatment (OST) have poorer health than the general population. Thus, they do not seek somatic health care to the extent that is medically motivated. Barriers hindering patients from seeking medical help through the conventional healthcare system result in a high degree of unmet healthcare needs. Barriers to, and facilitators of, OST patients’ healthcare

Time course changes to structural, mechanical and material properties of bone in rats after complete spinal cord injury

Objective: Characterise the spatiotemporal trabecular and cortical bone responses to complete spinal cord injury (SCI) in young rats. Methods: 8-week-old male Wistar rats received T9-transection SCI and were euthanised 2-, 6-, 10-or 16-weeks post-surgery. Outcome measures were assessed using micro-computed tomography, mechanical testing, serum markers and Fourier-transform infrared spectroscopy. R

Handläggning och behandling av diabetes under ramadan

Fasting during the month of Ramadan constitutes one of the five pillars of Islam. Islam is the second largest religion in Sweden. Fasting starts as the sun rises and the latest meal intake (Suhoor) is before the sun rises. The first meal intake (Iftar) is at the end of the fasting period, which is at sunset. Based on epidemiological data it is known that a large proportion of persons with diabetes

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Femtosecond laser-induced cyano chemiluminescence uses femtosecond filaments to tag molecules in a flow field, and velocity information of the flow field can be obtained by observing the displacement of the tagged molecules within a known time. The one-dimensional (1D) emitting line contains 1D velocity field information, but only the velocity at the central point can be given because it is unable

Polaronic Trions Induced by Strong Interfacial Coupling in Monolayer WSe2

The weak dielectric screening in 2D semiconducting transition metal dichalcogenides give rise to strongly bound quasiparticles, which provides a platform to investigate the diverse excitonic phenomena and correlated physics. However, how to effectively control these quasiparticles is still a challenge for their applications in optoelectronic and valleytronic devices. Herein, by means of fabricatin