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Monitoring of polychlorinated biphenyls in human blood plasma: methodological developments and influence of age, lactation, and fish consumption
Human plasma samples from 50 wives of fishermen have been analyzed with respect to PCBs. The non-ortho-substituted PCB congeners CB-126 and CB-169 were determined by mass spectrometry in negative ion chemical ionization mode, which demonstrated a limit of detection of 30 fg. The recoveries of the internal standards used for determination of ortho-substituted CBs were approximately 95%. Two methods
Acoustic differential extraction for forensic analysis of sexual assault evidence.
Forensic DNA analysis of samples obtained from sexual assault evidence relies on separation of male and female components of the recovered genetic material. The conventional separation method used by crime laboratories, differential extraction (DE), is one of the most time-consuming sample preparation steps, requires extensive sample handling, is difficult to automate, and often results in ineffic
Occupational exposure to organic dust, microorganisms, endotoxin and peptidoglycan among plants processing workers in Poland
The objective of present work was to determine and compare the components of bioaerosol in several sectors of plant processing industries. The Study was conducted in 10 Facilities engaged in herb and grain processing, flax threshing, grain storing, baking, and cereals production. The air samples were taken on glass fibre litters with an AS-50 sampler. We determined the concentrations of airborne m
Quality of life in the very elderly after cardiac surgery: a comparison of SF-36 between long-term survivors and an age-matched population.
The potential of isothermal calorimetry in monitoring and predicting quality changes during processing and storage of minimally processed fruits and vegetables
We review the potential of isothermal calorimetry as an analytical tool to provide an integrated view of the effect of different processing steps on the quality and shelf life of minimally processed fruits and vegetables. Variations in processing operations involved in product development in the food industry are studied through a factory scenario to show the versatility of the technique in monito
Theory of the ultrafast nonlinear response of terahertz quantum cascade laser structures
Using density matrix theory, the linear and ultrafast nonlinear optical properties of a recently developed terahertz quantum cascade laser are investigated. All relevant excitation regimes, from coherent Rabi flopping up to the scattering dominated stationary response, are covered by the theory. It is shown that the coherence transfer between different periods is important to describe optical effe
The role of low grade inflammation as measured by C-reactive protein levels in the explanation of socioeconomic differences in carotid atherosclerosis.
Background: The role of inflammation as part of the explanation of socioeconomic differences in carotid atherosclerosis has not been specifically investigated. Methods and Results: The associations between socioeconomic position (SEP), C-reactive protein (CRP), and preclinical carotid atherosclerosis were investigated in a general population sample of 3921 middle-aged Swedish men and women. Common
Physiological and clinical aspects of change in microvascular permeability
Ancient bacteria show evidence of DNA repair
Recent claims of cultivable ancient bacteria within sealed environments highlight our limited understanding of the mechanisms behind long-term cell survival. It remains unclear how dormancy, a favored explanation for extended cellular persistence, can cope with spontaneous genomic decay over geological timescales. There has been no direct evidence in ancient microbes for the most likely mechanism,
Technicolor and other QCD-like theories at next-to-next-to-leading order
Papillary secretion. Diagnostic assessment and treatment.
Papillary secretion is a common symptom in the breast clinic with many different underlying causes like intraductal papilloma, mammary duct ectasia, infected cysts and abscesses, breast cancer/carcinoma in situ (CIS) and rarely pituitary adenoma. The association with cancer/CIS is one of the two main concerns of the patient and must always be ruled out. The second item is that spontaneous and ongo
Automated PreScan function for scanning fluorescently stained 2D-PAGE gels
To automate the acquisition of images from fluorescently stained gels, the power of the excitation laser(s) must be optimized for each sample to prevent spot saturation (or to allow unimportant spots to saturate) yet still retaining sensitivity. In this work, we describe the implementation and effectiveness of a pre-scan function in a robotic solution for the automation of 2D gel scanning.
Fru Nanna Grönvalls bokbinderi
At the age of 33 and mother of seven children (the husband a shawowy figure), Mrs Grönvall started a small but soon renowed hand book bindery in the town of Malmö in Southern Sweden in 1893. Mostly self-taught herself, through the years she housed and trained several apprentices and journeyman of wich some opened binderies of their own. At the Arts and Crafts Exhibition in Malmö 1907 she was award
Electrophysiological correlates of auditory semantic priming in 24-month-olds.
While the N400 component in adults is sensitive to both semantic incongruity and semantic relatedness between stimulus items, the N400 in toddlers has only been shown as an incongruity effect so far. The present event-related potential (ERP) study aimed to investigate whether the N400 in toddlers also indexes semantic relatedness between single words. To address this issue, we developed a unimodal
Small intestinal manometry in patients with systemic sclerosis.
Photoactivation and Photoinhibition Are Competing in a Mutant of Chlamydomonas reinhardtii Lacking the 23-kDa Extrinsic Subunit of Photosystem II
The process of photoactivation has been studied in dark grown cells of Chlamydomonas reinhardtii. A mutant, FUD 39, lacking the Cl-concentrating 23-kDa psbP protein of photosystem II was found to have a decreased capability to perform photoactivation. The yield of the process never reached wild type level, and contrary to the wild type, it was highly dependent on the intensity of the activating li
Heterogeneity of cardiovascular risk among smokers is related to degree of carbon monoxide exposure.
Background: Between smokers matched for daily tobacco consumption there are marked variations of the cardiovascular risk. This follow up of the population based cohort “Men born in 1914” from Malmö, Sweden, explored whether this is accounted for by the levels of carbon monoxide (CO). Methods: Three hundred and sixty-five men without history of cardiovascular disease (CVD) were followed over 27
Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
For most associations of common single nucleotide polymorphisms (SNPs) with common diseases, the genetic model of inheritance is unknown. The authors extended and applied a Bayesian meta-analysis approach to data from 19 studies on 17 replicated associations with type 2 diabetes. For 13 SNPs, the data fitted very well to an additive model of inheritance for the diabetes risk allele; for 4 SNPs, th
Quaternary Structure Buildt from Subunuts Combining NMR and Small-Angle X-Ray Scattering Data
A new principle in constructing molecular complexes from the known high-resolution domain structures joining data from NMR and small-angle x-ray scattering (SAXS) measurements is described. Structure of calmodulin in complex with trifluoperazine was built from N- and C-terminal domains oriented based on residual dipolar couplings measured by NMR in a dilute liquid crystal, and the overall shape of
