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Introduction: Device-aided therapy may improve the quality of life (QoL) for people with advanced Parkinson's disease (PD) and poorly controlled symptoms with oral therapy. MANAGE-PD is a validated tool classifying patients based on symptom control and advanced treatment eligibility. This study focused on patient/caregiver reported outcomes and healthcare resource utilization among patients groupe

An association between high Galectin-4 (Gal-4) and prevalence of diabetes in subjects with heart failure (HF) has previously been reported. The purpose of this study was to confirm these findings, as well as to further investigate this association, in a Swedish HF population. In addition, a second aim was to explore Gal-4’s association with obesity and biomarkers of metabolism and heart failure. G

In March 2023, the European Forum for Research and Education in Allergy and Airways diseases (EUFOREA) organized its bi-annual Summit in Brussels with expert panel members of EUFOREA, representatives of the EUFOREA patient advisory board, and the EUFOREA board and management teams. Its aim was to define the research, educational and advocacy initiatives to be developed by EUFOREA over the next 2 y

Introduction and hypothesis: The aim of this study was to explore if antibiotic prophylaxis prevents postoperative infection after a posterior colporrhaphy. Methods: In this register-based nationwide cohort study data were collected from the “The Swedish National Quality Register of Gynecological Surgery” (GynOp). Women 18 years or older who underwent a primary posterior colporrhaphy between 1 Jan

This introductory chapter provides an overview of the history of Satanism. As an open identity, Satanism only became possible in a time when Christianity’s hold on legal systems and social norms weakened. In that sense, Satanism is a direct product of secularization. As a religious practice or coherent system of thought, Satanism did not exist any earlier than around the year 1900, when pioneers l

This chapter describes Carl William Hansen’s (aka Ben Kadosh) Luciferian manifesto, Den ny morgens gry (1906). Throughout his life, Hansen was a member of several masonic and occult organizations operating in Denmark and was well known (or perhaps notorious) in the Danish occult milieu. Even though Den ny morgens gry appears to be a very original work, it ties in with late nineteenth- and early tw

X-ray phase contrast imaging (X-PCI) is a powerful technique for high-resolution, three-dimensional imaging of soft tissue samples in a non-destructive manner. In this technical report, we assess the quality of standard histopathological techniques performed on formalin-fixed, paraffin-embedded (FFPE) human tissue samples that have been irradiated with different doses of X-rays in the context of a

Systematic evaluations are vital to support learning and enhance performance in a crisis response. There are quantitative methods available today for evaluating crisis response management (CRM), but there are limiting factors negatively affecting their potential; They often involve techniques difficult to implement in real events, lack reliability testing, provide outcomes questionable from a lear

Over the last thirty years, suggestions for how to develop defence capability have developed rapidly. However, supporting theory and structured concept development lag behind. Despite this imbalance, countries need to continuously spend resources on defence development. This study identifies central challenges in relation to the scientific perspectives and approaches needed to support the developm

Background and aims: Gestational diabetes is more common in many first-generation immigrant women in Europe and other Western countries. Less is known about second-generation immigrant women; such knowledge is needed to understand generational influences on diabetes risk. We aimed to study second-generation immigrant women regarding the presence of all types of diabetes during pregnancy. Methods a

Background: Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gained lot of attention as a regulatory epigenetic modification with prognostic and diagnostic implications for several cancers. However, there is no global study

The inclusive top-quark pair (tt¯) production cross-section σtt¯ is measured in proton–proton collisions at a centre-of-mass energy s = 5.02 TeV, using 257 pb−1 of data collected in 2017 by the ATLAS experiment at the LHC. The tt¯ cross-section is measured in both the dilepton and single-lepton final states of the tt¯ system and then combined. The combination of the two measurements yields σtt¯=67

Gaia Data Release 3 provides novel flux-calibrated low-resolution spectrophotometry for '220 million sources in the wavelength range 330 nm ≤ λ ≤ 1050 nm (XP spectra). Synthetic photometry directly tied to a flux in physical units can be obtained from these spectra for any passband fully enclosed in this wavelength range. We describe how synthetic photometry can be obtained from XP spectra, illust

Dimensionality reduction is an Exploratory Data Analysis (EDA) approach allowing for fast visualization of high-dimensional data and the possibility of discovering hidden systematic patterns within a data set. While linear dimensionality reduction techniques, such as Principal Component Analysis (PCA), are considered the golden standard in many areas of data science, they seem to be inadequate for

This work is focused on the modelling of experimental behaviour of a bone-shape sample made of aluminium alloy AW5083 under tension. This behaviour involves propagating instabilities, namely Lueders bands and the Portevin–Le Chatelier effect. A series of experiments was performed at room temperature for three loading rates, showing the instabilities and failure. In the paper a large strain thermov

Friction characteristics and wear of sheet-bulk metal forming tools featuring microstructured surfaces are simulated on the mesoscale. Computational homogenisation is used for surface cut-outs on which the structures are geometrically resolved and where friction laws model lower scale roughness. Two approaches are presented for the modelling of wear. A dissipation based Archard model is implemente

Background and objective Low-density computed tomography (LDCT) improved early lung cancer diagnosis but introduces an excess of false-positive pulmonary nodules data. Hence, accurate diagnosis of early-stage lung cancer remains challenging. The purpose of the study was to assess the feasibility of using circulating tumour cells (CTCs) to differentiate malignant from benign pulmonary nodules. Mate

This study explores the potential benefits of combining a wave-shaped piston geometry with post injection strategy in diesel engines. The wave piston design features evenly spaced protrusions around the piston bowl, which improve fuel-air mixing and combustion efficiency. The ‘waves’ direct the flames towards the bowl center, recirculating them and utilizing the momentum in the flame jets for more

Circular economy (CE) has been of utmost interest in the industry and research community in the preceding years. However, CE is still a nascent research field in the built environment context. As technological advances within CE are slowing, the incorporation of business models into the concept is deemed important to achieve the necessary transition. Circular business models within the built envir