A separation between the academic subjects statistics and mathematical statistics has existed in Sweden almost as long as there have been statistics professors. The same distinction has not been maintained in other countries. Why has it been kept for so long in Sweden, and what consequences may it have had?In May 2015, it was 100 years since Mathematical Statistics was formally established as an aA separation between the academic subjects statistics and mathematical statistics has existed in Sweden almost as long as there have been statistics professors. The same distinction has not been maintained in other countries. Why has it been kept for so long in Sweden, and what consequences may it have had?In May 2015, it was 100 years since Mathematical Statistics was formally established as an a

We describe and compare how methods based on the classicalRice’s formula for the expected number, and higher moments, of level crossingsby a Gaussian process stand up to contemporary numerical methods toaccurately deal with crossing related characteristics of the sample paths.We illustrate the relative merits in accuracy and computing time of the Ricemoment methods and the exact numerical method, We describe and compare how methods based on the classical Rice’s formula for the expected number, and higher moments, of level crossings by a Gaussian process stand up to contemporary numerical methods to accurately deal with crossing related characteristics of the sample paths.We illustrate the relative merits in accuracy and computing time of the Rice moment methods and the exact numerical meth

Hypothalamus (HT) is a brain structure which serves as a coordination center for several vital body functions. Craniopharyngioma (CP) is a pituitary tumor with high morbidity, primarily due to HT lesion. Among important consequences of CP are cognitive dysfunction and intractable weight gain due to HT obesity, resulting in high cardiovascular (CV) risk. A better understanding of the structural bra

Motivated by the recent development of fast and ultrasensitive thermometry in nanoscale systems, we investigate quantum calorimetric detection of individual heat pulses in the sub-meV energy range. We propose a hybrid superconducting injector-calorimeter setup, with the energy of injected pulses carried by tunneling electrons. It is shown that the superconductor constitutes a versatile injector, w

Aims and objectives: The aim of this study was to describe how EL was eased, as narrated by frail older people. Background: Existential loneliness (EL) is an unavoidable part of the human condition. It is a complex phenomenon that has been described as disconnection from life. If EL is acknowledged in the care of older people, the experience of EL can be reduced. Design: In this qualitative study,

This paper introduces a predictive combustion-engine controller for efficient fulfillment of constraints on peak pressure, exhaust temperature and NO emissions. The controller utilizes a in-cylinder pressure sensor, actuation of multiple fuel injections and numerical optimization. A physical model is used to predict pressure changes due to fuel-injection variation. The predicted pressure is used t

Here we show that treatment of the HPV16-positive tonsillar cancer cell line HN26 with DNA alkylating cancer drug melphalan-induced p53 and activated apoptosis. Melphalan reduced the levels of RNA polymerase II and cellular transcription factor Sp1 that were associated with HPV16 DNA. The resulting inhibition of transcription caused a rapid loss of the HPV16 early mRNAs encoding E6 and E7 as a res

Nanowires are presently investigated in the context of various biological and medical applications. In general, these studies are population-based, which results in sub-populations being overlooked. Here, we present a single cell analysis of cell cycle and cell movement parameters of cells seeded on nanowires using digital holographic microscopy for time-lapse imaging. MCF10A normal-like human bre

The aim of this study was to explore parents’ experiences of sleep and rest while admitted to hospital together with their ill child. When a child is hospitalized, it can be a traumatic experience for the entire family. Adaptation to the new situation and new parental responsibilities is necessary. Hospitalized children demand more supervision and care, making sleep disturbance a common challenge

Globally, transport increases its share of emissions and the transport sector desperately needs an efficient climate policy including efficient strategies to reduce unsustainable levels of car use. By providing insights into the profile of passenger mileage by car in relation to levels estimated to be sustainable in 2050, this work gives insight into who will, and who needs to, be affected by poli