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An unmanned ship can be designed without considering humancomfort, and can thus be constructed lighter, smaller and less expensive.It can carry out missions in rough terrain or be in areaswhere it would be dangerous for a human to operate. By not havingto support a crew, lengthy missions can be accepted, enabling, e.g.reconnaissance missions, or reducing emissions by lowering thespeed.Breakthrough
The standard Godunov type method used in computational fluid dynamics shows accuracy problems for low Mach number flows and for the kinetic energy at the highest wave numbers resolvable on a given grid. Both drawbacks become visible when simulating the decay of isotropic turbulence at the low Mach numbers typical for the respective experimental investigations. A modification to cure both problems
We considered nonlinear solvers inside implicit time integration schemes for the time dependent compressible Navier-Stokes equations. The existing solvers turn out to be adequate, but amenable to significant improvements. Regarding multigrid schemes, we demonstrated that reoptimizing a multigrid scheme for the case of a time dependent equation leads to significant improvements in convergence speed
We consider thermal fluid structure interaction to model industrial gas quenching in steel forging, where hot steel Is cooled using cold high pressured gas. This allows to define properties of the finished steel part, as for example yield strength, locally at low cost and without environmental problems. For the numerical simulation, a partitioned approach via a Dirichlet-Neumann coupling and a fix
We consider the coupling of the compressible Navier-Stokes equations with the heat equation as a model for cooling processes in steel forming. The semidiscrete coupled system is solved using stiffly stable SDIRK methods of higher order, where on each stage, a fluid-structure interaction problem is solved. textcopyright 2009 American Institute of Physics.
This paper presents a scalable and high-Throughput hybrid computing platform for the real-Time multi-particle based Linac (Linear accelerator) simulation model to be used at the European Spallation Source (ESS). The multi-particle simulation model with non-linear modeling is needed to provide a realistic behavior of the particle beam for reducing the losses at the superconducting structures. The c
This paper presents a cryptographic processor compliant with the security algorithms specified by the 3rd Generation Partnership Project (3GPP) specifications for Long Term Evolution (LTE). The proposed processor has been adapted to the needs of the low end portfolio technologies that compose the Internet of Things (IoT) market, which addresses low-Area, low-cost and low-data rate applications. Th
Type 1 (T1D) and type 2 (T2D) diabetes are triggered by a combination of environmental and/or genetic factors. Maf transcription factors regulate pancreatic beta (β)-cell function, and have also been implicated in the regulation of immunomodulatory cytokines like interferon-β (IFNβ1). In this study, we assessed MAFA and MAFB co-expression with pro-inflammatory cytokine signaling genes in RNA-seq d
The production of Z bosons in association with a high-energy photon (Zγ production) is studied in the neutrino decay channel of the Z boson using pp collisions at s√=13 TeV. The analysis uses a data sample with an integrated luminosity of 36.1fb−1 collected by the ATLAS detector at the LHC in 2015 and 2016. Candidate Zγ events with invisible decays of the Z boson are selected by requiring signific
Succinate dehydrogenase (Complex II; SDH) plays an important role in mitochondrial respiratory metabolism. The SDH complex consists of four core subunits and multiple cofactors, which must be assembled correctly to ensure enzyme function. To date, only an assembly factor (SDHAF2) required for FAD insertion into subunit SDH1 has been identified in plants. Here, we report the identification of Arabi
Background: Long-QT (LQT) syndrome mutation carriers have higher risk of cardiac events than unaffected family members even in the absence of QTc prolongation. Changes in T-wave morphology may reflect penetrance of LQT syndrome mutations. We aimed to assess whether T-wave morphology may improve risk stratification of LQT2 mutation carriers with normal QTc interval. Methods: LQT2 mutation carriers
Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this an
Introduction: Mechanical thrombectomy within 6 h after stroke onset improves the outcome in patients with large vessel occlusions. The aim of our study was to establish a model based on diffusion weighted and perfusion weighted imaging to provide an accurate prediction for the 6 h time-window in patients with unknown time of stroke onset. Patients and methods: A predictive model was designed based
Föreliggande rapport sammanfattar arbetet med att uppskatta vattenbalanser genom hydrologisk simulering för Malmö Botaniska Trädgård i Lindängelund, Malmö. Bedömning av maximalbehovet av bevattning inom biotopytorna visar på relativt små vattenflöden (totalt ca 6.2 l/s). Vid en antagen medelvattenhastighet om 10 cm/s (motsvarar ett lugnt flytande naturvattendrag) erhålls ett flöde på ca 80 l/s. Va
Background: International migrants could be considered as a risk group for being susceptible to vaccine preventable diseases such as measles and rubella. However, data on immunity in different migrant groups are scarce. Apart from asylum seekers and refugees, other immigrant groups might also be at risk. We have examined measles and rubella specific IgG antibodies among newly arrived adult immigra
Föreliggande rapport sammanfattar arbetet med att uppskatta vattenbalanser genom hydrologisk simulering för Malmö Botaniska Trädgård i Lindängelund, Malmö. Bedömning av maximalbehovet av bevattning inom biotopytorna visar på relativt små vattenflöden (totalt ca 6.2 l/s). Vid en antagen medelvattenhastighet om 10 cm/s (motsvarar ett lugnt flytande naturvattendrag) erhålls ett flöde på ca 80 l/s. Va
Objectives. Chest pain is a common complaint in the emergency department (ED), and it is a challenge to identify low-risk chest pain patients eligible for early discharge. We aimed to develop a simple objective decision rule to exclude 30-day major adverse cardiac events (MACE) in ED chest pain patients. Design. We analyzed prospectively included patients presenting with chest pain. Low risk patie
G protein-coupled receptor 30 (GPR30) is a G protein-coupled receptor (GPCR) that is attracting considerable attention in breast cancer and cardiometabolic regulation. Following reports that GPR30 is required for some rapid estrogen responses, e.g. increased cAMP production and ERK1/2 activity, in estrogen receptor (ER)-negative cells, GPR30 was renamed G protein-coupled estrogen receptor 1 (GPER1
The objective of the present study was to map the mechanism whereby G protein-coupled receptor 30 (GPR30), also called G protein-coupled estrogen receptor (GPER), stimulates extracellular signal-regulated kinase (ERK)1/2 signaling. GPR30 plays important roles in cancer and cardiometabolic regulation. We showed recently that GPR30 forms a plasma membrane complex through its C-terminal type I PSD-95
