Background: Several studies have investigated the association between metabolic syndrome (MetS) and physical activity (PA). However, further research is needed using objective measures of PA in free-living conditions, while also accounting for the time-variant nature of MetS. This study aimed to: (1) investigate the association between wearable device-measured step count and 5-year MetS incidence

This A-Z Guide offers an accessible and user-friendly overview of the essential concepts and terms needed to understand the implementation of the SDGs. Crafted in the form of an encyclopaedia, the volume presents 105 entries on important concepts and terms and their links to academic and policy debates. Each entry offers basic definitions of the concept or term at issue, followed by a brief discus

This study explored how propylene glycol (PG), menthol:thymol deep eutectic solvent (DES, molar ratio 6:4), and PG:DES blends modulate drug permeation by impacting the stratum corneum (SC). Porcine SC samples were exposed to PG, DES, and PG:DES blends with varying PG content (10 %, 50 %, or 90 %). The impact of these formulations on SC lipid extraction, lipid arrangement, and keratin's secondary s

Context. The bar pattern speed of the LMC has been computed based on data from Gaia DR3 using three different methods. One method suggested that the LMC might be hosting a bar that barely rotates, and is slightly counter-rotating with respect to the disc of the LMC, with a pattern speed of Ωp = −1.0 ± 0.5 km s−1 kpc−1. Aims. We aim to confirm that tidal interactions might prevent the bar hosted by

This report summarises the insights we developed by conducting a literature review of the dominant approaches and experiences of transdisciplinary urban research. We conducted a World Wide Web search to identify key academic and non-academic publications between 2010 and 2023 in the disciplines of Architecture, Planning, Geography, Urban Studies, and Sustainability Science. We focused on those con

This report provides a summary of 11 visualisations that have been developed by scholars who are engaged in transdisciplinary urban research. We identified the visualisations through a review of academic literature in the disciplines of Architecture, Planning, Geography, Urban Studies, and Sustainability Science between 2010 to 2023. Some of the visualisations are original while others are derived

This book provides a highly accessible and user-friendly overview of the essential concepts and terms related to the current global endeavour to implement the Sustainable Development Goals.With the first decade of the 15-year timespan of the 2030 Agenda now past, the SDGs show limited progress and several goals are even regressing. It is imperative that SDG implementation is accelerated until 2030

In 2013, the United Nations General Assembly established the High-level Political Forum on Sustainable Development (HLPF) as a central platform for the review and follow-up of the 2030 Agenda and the Sustainable Development Goals (SDGs). Every year, government representatives and societal stakeholders meet to assess progress of SDG implementation. The HLPF can be seen as a soft governance instrume

Client-Based Teaching provides multiple opportunities for students and teachers in the built environment disciplines (Architecture, Urban Design, Landscape Architecture, and Planning) to engage with real world problems in the classroom setting. It also offers new ideas and approaches to non-academic partners who are working to improve the urban realm. This document provides a short introduction to

Universities around the world are increasingly engaging with a range of stakeholders to co-produce knowledge by making explicit connections between student learning and real-world issues. These connections can enhance the education process while creating new opportunities for knowledge co- creation and active engagement between academic and non-academic actors. This report provides a summary of th

Indoleamine 2,3-dioxygenase 1 (IDO1) is the rate-limiting enzyme in tryptophan metabolism that plays a central role in immune regulation across a range of diseases, including cancer. Beyond its enzymatic role, IDO1 has a non-enzymatic function that remains poorly understood. This study explores how phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) modulates IDO1's structur

Introduction: The climate and biodiversity crises are interconnected, unprecedented, existential threats that cause disturbing emotions, such as anxiety, grief, and anger. While there is increasing research about antecedents and outcomes of such eco-emotions, less is known about how to cope with them constructively, to benefit both mental health and pro-environmental action. Objectives: This study

Objectives: Studies supporting therapeutic drug monitoring to biopharmaceuticals in SLE are scarce. We aimed to assess anti-drug antibody (ADA) occurrence in belimumab-treated SLE patients and associations between belimumab concentrations and clinical response, serological outcomes and adverse events. Methods. We included 100 patients treated with intravenous belimumab. Clinical data and biologica

Background: Bladder outlet obstruction, commonly resulting from benign prostatic hyperplasia or congenital urethral valves, is a prevalent cause of voiding dysfunction. This condition induces significant bladder hypertrophy, alters excitability, and increases residual urine. Obstruction has been extensively studied in experimental animal models using surgical obstruction. A frequent pathological e

International organizations within and outside the United Nations system provide platforms for multilateral cooperation and give impulses for national policymaking to promote the implementation of the Sustainable Development Goals (SDGs). They set agendas, coordinate efforts across regions and countries, offer technical assistance and expertise, compile data and monitor progress, and raise awarene

Study region: Lake Vänern, the largest lake in the European Union, located in Sweden. Study focus: The study aimed to develop a spatially complete and temporally continuous lake surface water temperature (LSWT) dataset by fusing satellite remote sensing data with reanalysis products. Five satellite-derived LSWT products, including the Moderate Resolution Imaging Spectroradiometer (MODIS), were eva

The role of food disgust on entamophagy acceptance is well established but further indepth analysis of how food disgust impacts other aspects that include a wider range of attitudes have been seldom investigated. The study employed a two-study mixed-methods approach to determine the impact of food disgust on consumer's perceptions of insects as food and feed. In study one, an online questionnaire

Background: Nodal assessment in gallbladder cancer remains challenging, particularly in incidental gallbladder cancer. This understages the number of patients with node-positive disease, resulting in prognostic inaccuracy and insufficient adjuvant treatment. This study aimed to identify risk factors for positive nodes in gallbladder cancer and to compare prognostic discrimination of available noda

Background: Post-traumatic stress disorder (PTSD) is a significant psychiatric comorbidity in individuals with chronic pain. To date, the link between PTSD and chronic pain has mostly been described using the outdated DSM-IV PTSD criteria. Stronger evidence utilizing the updated DSM-5 criteria is needed to ensure comparability with earlier prevalence rates. Methods: This observational study report