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Laser spectroscopy to meet some challenges in medicine

Laser based spectroscopic techniques can be used in the detection and therapy of many human diseases. Examples will be given from a variety of clinical areas, such as oncology, orthopedics and pediatrics, and also from the field of food safety and antibiotic control.

First x-ray nanoimaging experiments at NanoMAX

NanoMAX is a hard x-ray nanoimaging beamline at the new Swedish synchrotron radiation source MAX IV that became operational in 2016. Being a beamline dedicated to x-ray nanoimaging in both 2D and 3D, NanoMAX is the first to take full advantage of MAX IVs exceptional low emittance and resulting coherent properties. We present results from the first experiments at NanoMAX that took place in December

Do Higher Wages Reduce Knowledge Worker's Job Mobility? Evidence for Swedish Inventors

Based on linked employer-employee panel data on all Swedish inventors, this paper analyses how wages affect inventors' job mobility. It is commonly assumed that higher wages reduce mobility because they reduce the value of outside opportunities. We argue that higher wages also send performance signals to potential employers, who raise their wage offers in response. By disentangling the effects of

Argument-Based Bayesian Estimation of Attack Graphs : A Preliminary Empirical Analysis

This paper addresses how to identify attack relations on the basis of lay arguers’ acceptability-judgments for natural language arguments. We characterize argument-based reasoning by three Bayesian network models (coherent, decisive, and positional). Each model yields a different attack relation-estimate. Subsequently, we analyze to which extent estimates are consistent with, and so could potentia

Ekonomiska utvärderingar av organtransplantationer: En systematisk litteraturöversikt

Organtransplantation har under de senaste decennierna utvecklats från att vara en experimentell behandling till att bli huvudbehandling för en rad sjukdomar. Förbättringar i immundämpande behandlingar anses generellt vara en av huvudorsakerna till denna utveckling, som också har medfört bättre utfall i form av överlevnad och livskvalitet. Under samma tidsperiod har kostnaden per transplantation mi

Serum Concentration of Cystatin C, Factor D and β2‐Microglobulin as a Measure of Glomerular Filtration Rate

ABSTRACT. Serum concentrations of creatinine and of the three low molecular weight (LMW) proteins cystatin C, factor D of the complement system and β2‐microglobulin were measured in 135 consecutive patients, whose glomerular filtration rates (GFR) were determined by Cr‐EDTA. In the total patient series, the reciprocals of S‐creatinine and S‐cystatin C were numerically and, in males, significantly

Abnormal Metabolism of γ-Trace Alkaline Microprotein : The Basic Defect in Hereditary Cerebral Hemorrhage with Amyloidosis

ALTHOUGH the total incidence of cerebral hemorrhage is high, comparatively few reports concerning the familial occurrence of this disease have been published.1,2 In 1935 Arnason described 10 families with a high incidence of cerebral hemorrhage and concluded that a hereditary form of the disease was present in these families.3 Further clinicopathological investigations of the disease revealed an a

Värdet av nya läkemedel: en förstudie

Denna rapport redovisar en förstudie till SNS fleråriga forskningsprojekt som undersöker hur värdet av nya läkemedel kan bedömas ur ett brett samhällsperspektiv. En slutsats av förstudien är att det finns goda möjligheter att få bättre svar på många av de policyfrågor som ställs i läkemedelspolitiken, t ex om förskrivning och offentlig subventionering av nya läkemedel. De omfattande svenska patien

Optimization Based Motion Planning With Obstacles And Priorities

The goal of this work is to explore ways of generating state trajectories for dynamical systems subject to computational constraints, obstacles and priority assignment. The algorithms are developed for a miniature unmanned aerial vehicle (UAV) in a modular fashion and include (1) a genetic algorithm (GA) for solving the traveling salesman problem (TSP) with respect to priorities and obstacle avoid

The effect of in vitro gastrointestinal conditions on the structure and conformation of oat β-glucan

A plethora of studies have shown that the physicochemical properties of oat β-glucan determine its health benefits. However, the impact of the passage through the gastrointestinal tract on the conformational and structural characteristics is not fully understood. The present study aims to elucidate the structure and conformation of gently extracted oat β-glucan before and after in vitro gastric an

PM - kommentarer rörande MSBs rapporteringsverktyg för risk- och sårbarhetsanalyser

Myndigheten för samhällsskydd och beredskap (MSB) har efterfrågat synpunkter av Lunds Tekniska Högskola på det rapporteringsverktyg för risk- och sårbarhetsanalyser som MSB utvecklar. Verktyget är tänkt att underlätta förmedling och insamling av information som framkommer genom de risk- och sårbarhetsanalyser som kommuner och landsting samt myndigheter upprättar enligt föreskrifterna MSBFS 2010:6

Frequency selection for coda wave interferometry in concrete structures

This study contributes to the establishment of frequency recommendations for use in coda wave interferometry structural health monitoring (SHM) systems for concrete structures. To this end, codas with widely different central frequencies were used to detect boreholes with different diameters in a large concrete floor slab, and to track increasing damage in a small concrete beam subjected to bendin

Detecting damage events in concrete using diffuse ultrasound structural health monitoring durinbg strong environmental variations

Diffuse ultrasonic wave measurements used in structural health monitoring applications can detect damage in concrete. However, the accuracy is very susceptible to environmental variations. In this study, a large concrete floor slab was monitored using diffuse wave fields that were generated by continuous-wave transmissions between ultrasonic transducers. The slab was monitored for several weeks wh

Multicompartment simulations of NMDA receptor based facilitation in an insect target tracking neuron

Computational modelling of neurons on different scales provides not only methods to explore mechanisms observed in vivo but also for testing hypotheses that would be impossible physiologically. In this paper we present initial computational analysis of insect lobula small target motion detector (STMD) neurons. We simulate a multicompartment model in combination with a bioinspired model for front-e

Design of two-column batch-to-batch recirculation to enhance performance in ion-exchange chromatography

Preparative liquid chromatography is a separation technique widely used in the manufacturing of fine chemicals and pharmaceuticals. A major drawback of traditional single-column batch chromatography step is the trade-off between product purity and process performance. Recirculation of impure product can be utilized to make the trade-off more favorable. The aim of the present study was to investiga

Simultaneous Control of Soot Emissions and Pressure Rise Rate in Gasoline PPC Engine

Partially Premixed Combustion (PPC) is an advanced combustion concept resulting in high efficiencies and low emission levels by the use of high levels of EGR and pilot injections. The main limitation of PPC to use in practice lies in the high pressure rise rate, which causes issues on engine noise and durability. In addition, soot emissions face with the overshoot problem during the transient oper

Comparison of Gasoline and Primary Reference Fuel in the Transition from HCCI to PPC

Our previous research investigated the sensitivity of combustion phasing to intake temperature and injection timing during the transition from homogeneous charge compression ignition (HCCI) to partially premixed combustion (PPC) fuelled with generic gasoline. The results directed particular attention to the relationship between intake temperature and combustion phasing which reflected the changing