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Anorectal dysfunction after radical cystectomy for bladder cancer

Objective: To prospectively assess anorectal dysfunction using patient-reported outcomes using validated questionnaires, manovolumetry and endoanal ultrasound before and 12 months after RC. Patients and methods: From 2014 to 2019, we prospectively included 44 patients scheduled for RC. Preoperatively and 12 months after surgery, 41 patients filled in a low anterior resection syndrome score (LARS-s

Efficacy and safety of dronedarone versus placebo in patients with atrial fibrillation stratified according to renal function : Post hoc analyses of the EURIDIS-ADONIS trials

Background: The use of antiarrhythmic drugs (AADs) in patients with chronic kidney disease (CKD) is complex because impaired renal clearance can cause increased drug levels, and risk of intolerance or adverse events. Due to the propensity for CKD to occur alongside atrial fibrillation/atrial flutter (AF/AFL), it is essential that AAD safety and efficacy are assessed for patients with CKD. Hypothes

Knowing Other Minds : A Scorekeeping Model

The prepositional ‘in’ and possessive pronouns, e.g., ‘my’ and ‘mine,’ in the context of attributions of mental states, such as “in my mind” or “in your mind,” threaten to confuse attempts to account for knowledge of other minds. This paper distinguishes proper from improper uses of such expressions. I will argue that proper use of the prepositional ‘in’ and possessive pronouns in the context of m

Simulating Discharge in a Non-Dammed River of Southeastern South America Using SWAT Model

Within a single region, it is possible to identify opposite changes in flow production. This proved to be the case for several basins in southeastern South America. It remains challenging to the causes this behavior and whether changes in streamflow will continue at current levels or decline in the coming decades. In this study, we used the Soil Water Assessment Tool to simulate monthly river disc

Land Use and Cover Changes versus climate shift : Who is the main player in river discharge? A case study in the Upper Paraná River Basin

Assessing the relative contribution of Land Use and Cover Changes (LUCC) and climate changes on runoff still represents a great challenge for water resources management. This issue is particularly critical for the Upper Paraná River Basin (UPRB), one of the most important basins in South America and responsible for most of the production of food, ethanol, and electricity generation in Brazil. In t

Unsettled Rights : Afro-descendant recognition and ex-situ titling in Colombia

Ethnic recognition and collective titling have since the second half of the 20th century been promoted as ways of compensating for historical injustices and countering the destructive effects of capitalist development. While holding promise of autonomy, territorial rights, and resource control, they have also been seen as political technologies governing, spatially tying identities to place, and i

Kyrkligt arbete med fattiga, gåvor och ekonomisk utsatthet

Fattigvårdens bibliska grund, kyrklig historia och utformning i dagens samhälle tecknas av Elinn Leo Sandberg i kapitel 11. Hur ska fattigdom, människor som är fattiga, bemötas i ett välfärdssamhälle och hur bör kyrkan agera?The biblical foundation, church history and design of the work with poverty in today's society is drawn by Elinn Leo Sandberg in chapter 11. How should poverty, people who are poor, be treated in a welfare society and how should the church act?

Type 1 diabetes, cognitive ability and incidence of cardiovascular disease and death over 60 years of follow-up time in men

AIMS: There are few cohorts of type 1 diabetes that follow individuals over more than half a century in terms of health outcomes. The aim of this study was to examine associations between type 1 diabetes, diagnosed before age 18, and long-term morbidity and mortality, and to investigate whether cognitive ability plays a role in long-term morbidity and mortality risk.METHODS: In a Swedish cohort, 1

Tip of the iceberg? Country- and company-level analysis of drug company payments for research and development in Europe

Background Creating new therapies often involves drug companies paying healthcare professionals and institutions for research and development (R&D) activities, including clinical trials. However, industry sponsorship can create conflicts of interests. We analysed approaches to drug company R&D payment disclosure in European countries and the distribution of R&D payments at the country

Measurement of b-quark fragmentation properties in jets using the decay B± → J/ψK± in pp collisions at s√ = 13 TeV with the ATLAS detector

The fragmentation properties of jets containing b-hadrons are studied using charged B mesons in 139 fb−1 of pp collisions at s√ = 13 TeV, recorded with the ATLAS detector at the LHC during the period from 2015 to 2018. The B mesons are reconstructed using the decay of B± into J/ψK±, with the J/ψ decaying into a pair of muons. Jets are reconstructed using the anti-kt algorithm with radius parameter

α-synuclein interactions with lipid membranes

α-synuclein is an intrinsically disordered protein implicated in synaptic vesicle trafficking at the synapse. Accumulation of α-synuclein in the form of amyloid deposits coincides with the loss of dopaminergic neurons in Parkinsons disease. These deposits, referred to as Lewy Bodies, have been shown to contain membrane lipids together with the α-synuclein amyloid fibrils and other proteins. It was

Quantification of the absorption and scattering effects of diffusers in a room with absorbent ceiling

In ordinary public rooms, such as classrooms and offices, an absorbent ceiling is the typical first acoustic action. This treatment provides a good acoustic baseline. However, an improvement of specific room acoustic parameters, operating for specific frequencies, can be needed. It has been seen that diffusing elements can be effective additional treatment. In order to choose the right design, pla

Evidence for a Causal Relationship between Academic Achievement and Cigarette Smoking

Introduction: Academic achievement (AA) is associated with smoking rates. Can we determine the degree to which this relationship is likely a causal one? Methods: We predict smoking in male conscripts (mean age 18.2) assessed from 1984 to 1991 (N = 233 248) and pregnant females (mean age 27.7) receiving prenatal care 1972-1990 (N = 494 995) from AA assessed in all students at 16. Instrumental varia

Time-Resolved X-ray Diffraction Studies of Laser-Induced Dynamics in Solids

X-ray diffraction is an invaluable tool in the field of structural dynamics. In the work described in this thesis, time-resolved X-ray diffraction experiments were carried out to investigate ultrafast lattice dynamics. Ultrashort laser pulses were used to induce non-thermal melting and large-amplitude strain waves, and X-rays were used to probe these phenomena. Non-thermal melting was studied in i

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Uanset hvilken målestok man bruger for en retfærdig fordeling af det globale klimabudget må man konstatere, at den danske klimapolitik er langt fra tilstrækkelig ambitiøs.