OBJECTIVE: Maternal hemodynamics in pregnancy is associated with fetal growth and birth weight, which in turn is associated with offspring cardiovascular disease later in life. We therefore sought to quantify the extent to which birth weight is associated with cardiac structure and function in adolescence.METHODS: Participants (N=1,964, 55% females) from a UK birth cohort were examined with echoca

BACKGROUND: Women with history of hypertensive disorders of pregnancy (HDP) are at increased risk of early onset cardiovascular disease and type 2 diabetes (T2D). We aimed to investigate the extent to which HDP is also associated with midlife development of T2D and hypertension above and beyond established risk factors.METHODS: We included parous women who attended population-based structured clin

OBJECTIVES: To simplify the previously published Nottingham 12-year risk prediction model for knee osteoarthritis (OA) and examine whether it can be used to predict the 40-year risk of knee OA in young men.METHODS: We included 40 118 men aged 18 undergoing military conscription in Sweden 1969-70. Diagnostic OA codes were obtained from the Swedish National Patient Register 1987-2010. The original N

Searches for new heavy resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons, are presented using a data sample corresponding to 36.1 fb-1 of pp collisions at s=13 TeV collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting bosonic decay modes in the qqqq, ννqq, ℓνqq, ℓℓqq, ℓνℓν, ℓℓνν, ℓνℓℓ, ℓℓℓℓ,

“Mixing Metaphor” is a compilation of 12 chapters by prominent researchers, introduced by Raymond Gibbs, one of the main actors in the eld of metaphor studies. It is a highly timely contribution that lls a gap between the pre-theoret- ical notion of ‘mixed metaphors’, largely known to the (English-speaking) pub- lic as something to be avoided as it re ects poor style or even sloppy thinking, and s

An account of a poem inspired by a monument in the gardens of a stately home in Denmark.

BACKGROUND: Childhood cancer survivors have an increased risk of cardiovascular disease (CVD) and diabetes mellitus. Because diabetes is a potentially modifiable risk factor for CVD in the general population, it is important to understand how diabetes affects the risk of CVD among childhood cancer survivors. METHODS: This study examined the risk of CVD among survivors with diabetes and 142,742 pop

Ethyl 2-methyl-1,3-dioxolane-2-acetate (CAS # 6413-10-1) was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that ethyl 2-methyl-1,3-dioxolane-2-acetate is not genotoxic. Data from ethyl 2-methyl-1,3-dioxolane-2-acetate show that there are no safety conce

This article uses Neil M. Denari’s HL23 condominium tower in West Chelsea, New York City, as the lens through which to focus on the architectural design pathway in discretionary reviews to negotiate architectural form and bulk restrictions. The argument states that creative architectural forms can appropriate an unorthodox site configuration in accord with planning objectives and that review proce

This paper elucidates a disciplinary context for an emergent buildingtype dubbed Accessory Dwelling Unit, or ADU. Today, ADU developmentsadd density to metropolitan Los Angeles by undermining the low densityprinciples of single-family residential zoning. Surfacing withinthe jurisdiction formally known as the City of Los Angeles, the ADUsupplements city planning in the transformation of suburbia. T

ZHUuGROUND14 was an architectural workshop pursued at the City University of Hong Kong, 17-19 May 2014, and in collaboration with the Research Institute for Experimental Architecture (RIEA.ch). Taking the retaining wall as intellectualcompound, the workshop engaged in a large scale modelling exercise, which had been orchestrated to improve the critical skills of the architecture students. ZHUuGROU

This article takes the plan drawing of Richard Meier’s Westbeth Artists’ Colony in Greenwich Village as a lens through which to examine a chain of events that formalised what today is referred to as loft architecture. Westbeth was the first legal loft building in the USA. Approved by the local planning administration in March, 1968, and completed in May, 1970, the building was the successful culmi

The proliferation of shadow housing in the post-suburban landscape of Los Angeles tells a story about the inadequacy of R1 zoning to respond to escalating calls for new and more resilient housing types. Neither romanticizing nor condemning illegal housing, this article takes the shadow houses of L.A. as context for a critical re-evaluation of the R1. By consulting the tools of architectural repres

On the banks of the Göta River, the city of Gothenburg is undergoing a transformation that characterizes many urban waterfronts today, as shipping, fishing, and naval uses are replaced by a high demand for new housing. What is unique to Gothenburg is its vision of a RiverCity that is diverse, environmentally sound, and vibrant. It is imperative, however, to take stock of the successes and failures