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Midwifery continuity of care in the Nordic countries : A scoping review protocol

Objective: To provide a protocol for a scoping review aimed to map, identify, analyze and describe studies on women and their infants receiving Midwifery Continuity of Care in the Nordic countries. AbstractIntroduction: Midwifery Continuity of Care (MCoC) throughout pregnancy, birth, and the postnatal period has been associated with improved outcomes and higher satisfaction of care among women. In

Income and education affect prognosis and treatment in symptomatic myeloma : A population-based study on 8672 multiple myeloma patients diagnosed 2008–2021 from the Swedish myeloma registry

Despite advancements in multiple myeloma treatment, prognostic variability persists. We investigated the impact of income and education on treatment and survival in a country with publicly funded healthcare. We analysed data from the Swedish Myeloma Registry (2008–2021) linked to national registers. Cox models assessed survival, adjusting for demographics and comorbidities. Treatment patterns were

A statistical approach for water movement in the unsaturated zone

This work presents a statistical approach for estimating and analyzing the downward transport pattern and distribution of soil water by the use of pattern analysis of space-time correlation structures. This approach, called the Space-time Correlation Field, is mainly based on the analyses of correlation functions simultaneously in the space and time domain.The overall purpose of this work is to de

Clinical significance of a new diagnosis of atrial fibrillation in patients with vascular disease

Background: The Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial enrolled patients with vascular disease but excluded patients requiring oral anticoagulation. Objective: We aimed to explore the clinical significance of a new diagnosis of atrial fibrillation (AF) during follow-up. Methods: New AF was identified from hospitalization, study drug discontinuation, and

The influence of three-gendered grammatical systems on simultaneous bilingual cognition : The case of Ukrainian-Russian bilinguals

This paper examines the linguistic relativity principle (Whorf, 1956) by investigating the impact of grammatical gender on cognition in simultaneous bilinguals of three-gendered Ukrainian and Russian. It examines whether speakers of three-gendered languages show grammatical gender effects on categorisation, empirically addressing claims that such effects are insignificant due to the presence of th

The Alzheimer's Association Global Biomarker Standardization Consortium (GBSC) plasma phospho-tau Round Robin study

INTRODUCTION: The Alzheimer's Association Global Biomarker Standardization Consortium conducted a blinded case–control study to learn which phosphorylated tau (p-tau) assays provide the largest fold-changes in Alzheimer's disease (AD) versus non-AD and show commutability in measuring patient samples and candidate certified reference materials (CRMs). METHODS: Thirty-three different p-tau assays me

A Review of International Approaches for Development of Climate Reference Periods – for Hygrothermal Analysis of Buildings

In recent years, Sweden has seen substantial changes to its building designs, especially regarding the envelope and ventilation systems, across both renovations and new constructions. Although enhancements like better insulation and new building materials have boosted energy efficiency, they have also led to moisture-related problems such as stains, mold, and decay. To address these issues, heat a

SELective defunctioning Stoma Approach in low anterior resection for rectal cancer (SELSA) : Protocol for a prospective study with a nested randomized clinical trial investigating stoma-free survival without major LARS following total mesorectal excision

Aim: Accumulated data suggest that routine use of defunctioning stoma in low anterior resection for rectal cancer may cause kidney injury, bowel dysfunction and a higher risk of permanent stomas. We aim to study whether avoidance of a diverting stoma in selected patients is safe and reduces adverse consequences. Methods: SELSA is a multicentre international prospective observational study nesting

Birthweight and risk of chronic kidney disease after a type 2 diabetes diagnosis in the DD2 cohort

Aims/hypothesis: Low birthweight (LBW) is associated with younger age, less obesity and more hypertension among people recently diagnosed with type 2 diabetes, as well as increased cardiovascular morbidity and mortality risk. It is not known whether LBW is associated with an increased risk of incident chronic kidney disease (CKD) among people with a type 2 diabetes diagnosis. Methods: Original mid

Confirmatory Biopsy Outcomes in Patients with Grade Group 2 Prostate Cancer : Implications for Early Management

Background and objective: Guideline recommendations regarding early management of grade group (GG) 2 prostate cancer with confirmatory biopsy (cBx) are not well established. Our aim was to determine which patients with GG 2 cancer should undergo cBx before treatment decision-making by evaluating the probability of downgrading to GG 1 or no cancer on cBx. Methods: This was a single-institution retr

Cardiac ATP production and contractility are favorably regulated by short-term S100A9 blockade after myocardial infarction

Introduction: The infarcted heart is energetically compromised exhibiting a deficient production of adenosine triphosphate (ATP) and the ensuing impaired contractile function. Short-term blockade of the protein S100A9 improves cardiac performance in mice after myocardial infarction (MI). The implications upon ATP production during this process are not known. Objectives: This study evaluates whethe

IgA vasculitis nephritis - outcomes in adult-onset disease

Objectives: IgA vasculitis (IgAV) in adults has been relatively under-investigated. Since outcomes are worse in other forms of vasculitis with increasing age, we investigated the outcomes of IgAV comparing younger adults (18-34), middle-aged adults (35-64) and elderly patients (≥64 years) focusing on kidney outcomes. Methods: We identified patients with renal biopsy-confirmed IgAV nephritis and co

Sleep-Administered ketamine/psychedelics : A streamlined strategy to address two challenges in research on ketamine and psychedelics

The dissociative effects of ketamine and psychedelics might be associated with their rapid antidepressant properties, raising questions about whether these effects are necessary for their therapeutic action. Additionally, the distinct dissociative experiences often reported by patients in clinical trials may reveal whether they receive an active treatment or a placebo, potentially introducing bias

Uncertainty-Aware Decision-Making and Planning for Autonomous Forced Merging

In this paper, we develop an uncertainty-aware decision-making and motion-planning method for an autonomous ego vehicle in forced merging scenarios, considering the motion uncertainty of surrounding vehicles. The method dynamically captures the uncertainty of surrounding vehicles by online estimation of their acceleration bounds, enabling a reactive but rapid understanding of the uncertainty chara

Robust motion planning for autonomous vehicles based on environment and uncertainty-aware reachability prediction

Planning and navigation in real-time traffic is challenging, since the driving environment (e.g., road network and infrastructure) is complex and the accurate prediction of surrounding vehicles is hard. To address this, this paper proposes an environment and uncertainty-aware robust motion-planning strategy. The method achieves environment awareness by considering road-geometry constraints in the

Robust Predictive Motion Planning by Learning Obstacle Uncertainty

Safe motion planning for robotic systems in dynamic environments is nontrivial in the presence of uncertain obstacles, where estimation of obstacle uncertainties is crucial in predicting future motions of dynamic obstacles. The worst case characterization gives a conservative uncertainty prediction and may result in infeasible motion planning for the ego robotic system. In this article, an efficie