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The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantatio
BACKGROUND: A randomised controlled trial found that a structured mindfulness group therapy (MGT) programme was as effective as treatment as usual (mostly cognitive-behavioural therapy) for patients with a diagnosis of depression, anxiety or stress and adjustment disorders in Sweden (ClinicalTrials.gov: NCT01476371).AimsTo perform a cost-effectiveness analysis of MGT compared with treatment as usu
This article explores the advocacy activities of the Church of Sweden. The historical co-optation of the Church by the state, a Lutheran theological heritage, and a trend from “voice to service” within Swedish civil society might discourage stronger political activism by the Church. The following research questions are answered: How does the extent of the advocacy activities of the Church of Swede
Chile and Norway are two ‘natural resource-intensive economies’, which have had different development trajectories, yet are closely similar in industrial structure and geophysical conditions. This paper seeks to contribute to the debate about how and why some economies based on natural resource activities have been more dynamic and innovative than others by indicating contributing factors of key d
Background: Preventing ischaemic stroke attracts significant focus in atrial fibrillation (AF) cases. Less is known on the association between socioeconomic factors and mortality and cardiovascular outcomes in patients with AF. Methods: Our study population included adults (n=12 283) ≥45 years diagnosed with AF at 75 primary care centres in Sweden 2001-07. Cox regression was used to calculate haza
SnTe topological crystalline insulator nanowires have been grown by molecular beam epitaxy on graphene/SiC substrates. The nanowires have a cubic rock-salt structure, they grow along the [001] crystallographic direction and have four sidewalls consisting of {100} crystal planes known to host metallic surface states with a Dirac dispersion. Thorough high resolution transmission electron microscopy
Aims: Sudden cardiac arrest (SCA) accounts for 10% of adult mortality in Western populations. We aim to identify potential loci associated with SCA and to identify risk factors causally associated with SCA. Methods and results: We carried out a large genome-wide association study (GWAS) for SCA (n = 3939 cases, 25 989 non-cases) to examine common variation genome-wide and in candidate arrhythmia g
Background: Previous studies support a tumor-suppressor role for LRRC3B across various types of cancers. We aimed to investigate the association between DNA methylation of LRRC3B and overall survival (OS) for patients with early-stage non-small cell lung cancer (NSCLC).Methods: This study included 1,230 patients with early-stage NSCLC. DNA was extracted from lung tumor tissues and DNA methylation
En kvarstående abdominell rektusmuskeldiastas hos kvinnor efter förlossning är vanlig och kan medföra försämrad bålmuskelfunktion och hos en del patienter avsevärt nedsatt livskvalitet.Den vetenskapliga evidensen för val av behandling av abdominell rektusmuskeldiastas är svag. Fysioterapi med bålstabiliserande träning bör vara förstahandsval.Hos en liten grupp med mer uttalade besvär där fysiotera
Lateralized behaviours are widespread among the animals, including insects with their miniature brains, perhaps being a way of maximising neural capacity (reviewed in [1,2]). However, evidence for functional asymmetries in the neural circuitry itself is scarce. Here, using bilateral simultaneous recordings from the ex vivo nervous system of desert locusts, we show that the neural control of their
