Endoscopy is not a modern invention but the history of endoscopy goes back to ancient times in Egypt and Greece when speculums were used to inspect the nose cavity, vagina and anorectum. The modern era of endoscopy started in the 19th century with the development of straight metallic tubes with primitive light sources, such as Bozzini´s »lichtleiter« and Desormeaux´s »endoscope«. The first gastros

Loss and Damage (L&D) has been the subject of contentious debate in international climate policy for several decades. Recently, formal mechanisms on L&D have been established, but arguably through unclear language. This ambiguity is politically important, but researchers and practitioners require clearer understandings of L&D. Here we report on the first in-depth empirical study of act

Adrenal incidentalomas are seen in about five percent of abdominal CT examinations, and in most cases represent non-hormone-producing adrenocortical adenomas, but hormone-producing or malignant lesions occur. Revised Swedish guidelines for the evaluation and management of adrenal incidentalomas based on recently published European guidelines are presented. The importance of a thorough radiological

Objective. To evaluate a set of psychometric properties (i.e., data completeness, targeting, and external construct validity) of the Parkinson's disease Activities of Daily Living Scale (PADLS) in people with Parkinson's disease (PD). Specific attention was paid to the association between PADLS and PD severity, according to the Hoehn & Yahr (H&Y) staging. Methods. The sample included 251 p

User Generated Content (UGC) is projected to make up a significant part of the total Internet traffic in the future. As such, it will significantly contribute to the total cost for Internet traffic worldwide. Arguably, UGC is a suitable content type for which the Internet Service Providers (ISPs) can take initiative and enter the content delivery market. However, despite its significance, UGC cont

We analyse the relationship between international sourcing, measured as imports of intermediate inputs, and the technical efficiency of firms in the information and communications technologies (ICT) manufacturing industry in Sweden. Using stochastic frontier analysis, we provide evidence that global sourcing improves firms’ capabilities to combine and re-combine inputs in productive ways, thereby

The first checklist of the odonates from Guyana is presented, including 46 new species records. Literature sources are provided for all species and for the new records full locality data, color scans or field photographs, taxonomic and biological notes, and maps for those species whose distribution range is increased considerably.

Apolipoprotein A-I (apoA-I) in high-density lipoprotein (HDL) provides cardiovascular protection. Synchrotron radiation circular dichroism (SRCD) spectroscopy was used to analyze the dynamic solution structure of the apoA-I protein in the apo- and HDL-states and the protein structure conversion in HDL formation. Wild-type apoA-I protein was compared to human variants that either are protective (R1

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the nuclear receptor (NR) superfamily of transcription factors. We assessed the ability of these NRs to form heterodimers with other members of the human NRs representing all major subgroups. The TLX ligand-binding domain (LBD

Enhancement and control of forced convection heat transfer is important in many engineering applications and ducts of various surface complexity are used. Surface modifications like rib-roughening, grooves, dimples, protrusions, etc., are commonly applied in applications such as compact heat exchangers, electronics cooling as well as cooling in gas turbines and aircraft engines. This chapter gives

We present the use of capillary driven flow over patterned surfaces to achieve cheap and simple, but powerful separation of biologically relevant particle systems. The wide use of microfluidics is often hampered by the propensity for devices to clog due to the small channel sizes and the inability to access the interior of devices for cleaning. Often the devices can only be used for a limited dura

Electric vehicles (EVs) are increasingly seen as a desirable sustainable solution for the transport sector, and public procurement is often highlighted as one tool to stimulate a market. In this paper, we analyse the role of Swedish municipalities in relation to public procurement and especially whether and in such cases how municipalities in Sweden use public procurement as an instrument to enhan

Background: Methyl mercury (MeHg) is a well-known neurotoxin and evidence suggests that also low level exposure may affect prenatal neurodevelopment. Uncertainty exists as to whether the maternal MeHg burden in Norway might affect child neurodevelopment. Objective: To evaluate the association between prenatal mercury exposure, maternal seafood consumption and child language and communication skill

A precise age scale based on annual layer counting is essential for investigating past environmental changes from ice core records. However, subannual scale dating is hampered by the irregular intraannual variabilities of oxygen isotope (δ18O) records. Here we propose a dating method based on matching the δ18O variations between ice core records and records simulated by isotope-enabled climate mod

AIMS/HYPOTHESIS: Genetic and environmental factors are believed to cause type 1 diabetes. The aim of this study was to investigate the influence of maternal BMI and gestational weight gain on the subsequent risk of childhood type 1 diabetes.METHODS: Children in the Swedish National Quality Register for Diabetes in Children were matched with control children from the Swedish Medical Birth Register.

Biogeochemical cycling of elements largely occurs in dissolved state, but many elements may also be bound to natural nanoparticles (NNP, 1-100 nm) and fine colloids (100-450 nm). We examined the hypothesis that the size and composition of stream water NNP and colloids vary systematically across Europe. To test this hypothesis, 96 stream water samples were simultaneously collected in 26 forested he

By understanding laws of nature as geometrical rather than linguistic entities, this paper addresses how to describe theory structures and how to evaluate their continuity. Relying on conceptual spaces as a modelling tool, we focus on the conceptual framework an empirical theory presupposes, thus obtain a geometrical representation of a theory’s structure. We stress the relevance of measurement pr