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Prenatal diagnosis : The co-production of knowledge and values in medical research and public debate

This chapter examines how prenatal diagnosis was discussed and interpreted when translated from laboratories and clinics into the public arena. It focusses on debates about policy and regulation in the early 1980s. Drawing on the concept of co-production the chapter argues that when groups outside the medical context discussed prenatal diagnosis, other values and norms were mobilized. Thus, in ordThis chapter examines how prenatal diagnosis was discussed and interpreted when translated from laboratories and clinics into the public arena. It focusses on debates about policy and regulation in the early 1980s. Drawing on the concept of co-production the chapter argues that when groups outside the medical context discussed prenatal diagnosis, other values and norms were mobilized. Thus, in ord

Introduction to Game Love

This is the introduction to the anthology Game Love:Essays on Play and Affection. The first 10 pages were written by Jessica Enevold and the ensuing chapter presentations by Esther MacCallum-Stewart. The whole book was edited together by Enevold & MacCallum-Stewart based on an idea by Jessica Enevold. The Introduction explains the background of the anthology, including an introduction to the o

Highlights of the novel dewaterability estimation test (DET) device

Many industries, which are producing sludge in large quantities, depend on sludge dewatering technology to reduce the corresponding water content. A key design parameter for dewatering equipment is the capillary suction time (CST) test, which has, however, several scientific flaws, despite that the test is practical and easy-to-perform. The standard CST test has a few considerable drawbacks: its l

Views on everyday life among adults with spina bifida : an exploration through photovoice

The aim of this study was to actively integrate expertise of persons living with spina bifida, to explore conditions embedded in their everyday life. This was important because young adults with spina bifida risk not being able to fully participate in the community on equal terms and in accordance with their own preferences. Photovoice, a community-based participatory research approach, was utiliz

Introduction

This article focuses on adjudication of Muslim family law in countries that range from the Middle East and North Africa to South-East Asia. It begins by shortly summarizing the development of shari'a in pre-modern times, up until the 19th century. We discuss the basic features of marriage among classical jurists and argue that the close connection known today between the family and Islamic law can

Solar Longitude Distribution of High-energy Proton Flares : Fluences and Spectra

The distribution of the longitudes of solar flares associated with the high-energy proton events called ground level events (GLEs) can be approximated by a Gaussian with a peak at ∼W60, with a full range from ∼E90 to ∼W150. The longitudes of flares associated with the top third (24 of 72) of GLEs in terms of their >430 MeV fluences (F 430) are primarily distributed over E20-W100 with a skew toward

Bone mineral as a drug-seeking moiety and a waste dump a Review

Bone is a dynamic tissue with a quarter of the trabecular and a fifth of the cortical bone being replaced continuously each year in a complex process that continues throughout an individual’s lifetime. Bone has an important role in homeostasis of minerals with non-stoichiometric hydroxyapatite bone mineral forming the inorganic phase of bone. Due to its crystal structure and chemistry, hydroxyapat

The Role of Graffiti Game Boards in the Understanding of an Archaeological Site : The Gebel el-Silsila Quarries

Graffiti game boards attest to the presence of historical populations at an archaeological site and, in some cases, assist in dating an archaeological context. While games suggest the presence of a social activity, their contextual significance compared to the graffiti of texts and images, pottery finds, and other diagnostic tools of archaeology is open to further enquiry. The presence of multiple

Analysis and Design of a 17-GHz All-npn Push-Pull Class-C VCO

A push-pull oscillator topology that uses only one type of active device is proposed in this article. A magnetic transformer is leveraged to set positive feedback around a common-collector differential npn transistor pair, implementing the push-pull operation. This results in half the bias current for a given amplitude of oscillation, compared to more standard oscillator topologies. A thorough pha

Is it possible to gain energy at work? A questionnaire study in primary health care

Abstract Objectives: The area of regenerative work is still close to unexplored. The aim was to explore the possibility for employees to gain energy at work. Methods: Questionnaire to all employees (n = 599) from different professions in public and private primary health care centers in one health care district in Sweden. The questionnaire, which had a salutogenic perspective, included information

Mammographic density as an image-based biomarker of therapy response in neoadjuvant-treated breast cancer patients

Purpose: Personalized cancer treatment requires predictive biomarkers, including image-based biomarkers. Breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT) are in a clinically vulnerable situation with the tumor present. This study investigated whether mammographic density (MD), assessed pre-NACT, is predictive of pathological complete response (pCR). Methods: A total of 495 BC

From Awkwardness to Action Christian Voluntarism in Denmark Beyond the Sector Model of Civil Society

The article challenges the theoretical “sectoral model” of civil society through a historical case study and offers an alternative actor-centered approach inspired by American pragmatism. First, three separate strands of research are identified that each conceptualize civil society as a sector with institutional independence, a single normative logic, and fixed roles. Building on archival material

Development and validation of a quantitative electron microscopy score to assess acute cellular stress in the human exocrine pancreas

The pancreas is particularly sensitive to acute cellular stress, but this has been difficult to evaluate using light microscopy. Pancreatic ischaemia associated with deceased organ donation negatively impacts whole-organ and isolated-islet transplantation outcomes. Post-mortem changes have also hampered accurate interpretation of ante-mortem pancreatic pathology. A rigorous histological scoring sy

Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223

Objective: Dose optimization and pharmacokinetic evaluation of α-particle emitting radium-223 dichloride (223RaCl2) by planar γ-camera or single photon emission computed tomography (SPECT) imaging are hampered by the low photon abundance and injected activities. In this study, we demonstrate SPECT of 223Ra using phantoms and small animal in vivo models. Methods: Line phantoms and mice bearing 223R

A holistic framework for development and assessment of risk-informed performance-based building regulation

Fire safety provisions in building regulation are about managing risk. In order to appropriately characterize and incorporate risk measures into building regulation, it is helpful to view building regulatory systems (BRS) as complex socio-technical systems (STS), wherein there are interactions between institutions, technology and people, which ideally work together to mitigate risk to a societally

Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting

The clinical value of the polygenetic component of blood pressure (BP) is commonly questioned. We evaluated a genetic risk score for BP (BP-GRS858), based on the most recently published genome-wide association studies variants that were significantly associated with either systolic BP or diastolic BP, for prediction of hypertension and cardiovascular end points. The genotyping was performed in 2 u

Cyberbullying and cybervictimization among preadolescents : Does time perspective matter?

Time perspective has been recognized as an important psychological dimension with a pervasive and powerful influence on human behavior. To the authors’ knowledge, no studies have focused on the relationship between time perspective and cyberbullying behavior. The first aim of this research is to fill this gap by investigating the relationship between different time perspectives and both cyberbully

The accuracy of drainage network delineation as a function of environmental factors : A case study in Central and Northern Sweden

Drainage networks delineated from Digital Elevation Models (DEMs), are the basis for the modelling of geomorphological and hydrological processes, biogeochemical cycling, and water resources management. Besides providing effective models of water flows, automatically extracted drainage networks based on topography can diverge from reality to varying degrees. The variability of such disagreement wi