How the brain represents the external world is an unresolved issue for neuroscience, which could provide fundamental insights into brain circuitry operation and solutions for artificial intelligence and robotics. The neurons of the cuneate nucleus form the first interface for the sense of touch in the brain. They were previously shown to have a highly skewed synaptic weight distribution for tactil

Abstract OBJECTIVE To assess the role of four biomarkers of neuroendocrine activation and endothelial dysfunction in the longitudinal prediction of fragility fractures. METHODS We analysed a population-based prospective cohort of 5415 community-dwelling individuals (mean age, 68.9±6.2 years) enrolled in the Malmö Preventive Project followed during 8.1±2.9 years, and investigated the longitudinal Objective To assess the role of four biomarkers of neuroendocrine activation and endothelial dysfunction in the longitudinal prediction of fragility fractures. Methods We analysed a population-based prospective cohort of 5415 community-dwelling individuals (mean age, 68.9±6.2 years) enrolled in the Malmö Preventive Project followed during 8.1±2.9 years, and investigated the longitudinal associati

INTRODUCTION: Comprehensive geriatric assessment (CGA) is a multidimensional, interdisciplinary diagnostic process used to determine the medical, psychological and functional capabilities of frail older people. The primary aim of our current study is to confirm whether CGA-based outpatient care is superior than usual care in terms of health-related outcomes, resource use and costs.METHODS AND ANAL

Porous silicon with immobilized recognition biomolecules is an attractive platform for many microfluidic chip-based bioanalytical applications. We review the progress in the field since its earliest developments in the 1990s. An improved assay for early detection of prostate cancer has reached clinical evaluation, but there are also exciting developments in both aptamer-based biosensing and mass s

Abstract: The notion of a circular economy (CE) developed out of the work of Kenneth Boulding and others concerned about Earth’s limited resources and its capacity for regeneration. The concept has recently become the heart of an economic perspective influencing governments, companies, and researchers. Core topics examined by those researchers include resource use, economic value, and systems thin

Purpose: The purpose of this paper is to investigate the thermal performance of the cooling plates with conventional straight channel and wavy channel designs. Design/methodology/approach: A three-dimensional model involving coupled fluid flow and heat transfer processes is developed to study the thermal performance of the cooling plates. The effects of wavelength and amplitude on the cooling perf

This book presents, for the first time, the unpublished manuscripts of Lars Hörmander, written between 1951 and 2007. Hörmander himself organised the manuscripts and also wrote the notes explaining their origins, presenting the material in the form he fully intended it to be published in. As his daughter, Sofia Broström, mentions in the Foreword, towards the end of his life, Hörmander "carefully w

Energy efficiency regulations are one of the important policy packages employed for climate mitigation. Recent evaluations from the USA and the European Union (EU) indicate that the setting of minimum mandatory energy performance standards (MEPS) for different products-such as electric motors, TVs, and dishwashers-are among the best-performing climate policies and that these regulations are also c

Volymen gavs ut i samband med utställningen på Deutsches Historisches Museum i Berlin och ger en överblick över de intensiva kulturella kontakterna mellan Tyskland och Skandinavien under "det långa 1800-talet". Forskare från Tyskland, Norge, Sverige och Danmark bidrar med artiklar om politisk kultur, nationalstaternas identitetssökande, växelverkan inom konst, musik och litteratur, konstnärskoloni

Behandlar ett förbisett arkivmatrial som visar vilken roll Oscar (I) och Josephina som kronprinspar i Sverige spelade i de arkitektoniska och konstnärliga förbindelserna mellan Stockholm och München från 1820-talet till och med 1840-talet, däribland kontakterna med Leo von Klenze och Ludwig Schwanthaler.

IntroductionIncreasing oil prices and growing environmental concerns in recent years have driven the development of renewable biofuels. Stimulated by this, the European production of bioethanol, which is produced by fermentation of sugar components in biomass, has nearly doubled in the last two years increasing from 913 million litres in 2005 to 1,565 million litres in 2006. The continuation of th

Artikeln behandlar ett specifikt motiv i den franska impressionismen från 1860-talet: den bortvända kvinnogestalten, ofta i promenaddräkt. Här berörs relationen till carte-de-visite-fotografiets helfiguriga promenadmotiv och en äldre figurkomposition från Watteau.

Software developers are gaining increasing influence within every company they work for and work with. Engaging at C-level is no longer sufficient: the software developer is now a powerful force in decision-making.This book is intended to be the “textbook” for those working - or starting - in developer marketing. It will teach you how to engage with developers to build a two-way relationship that

Nanofiltration is nowadays established in many industries for the separation and purification of aqueous solutions. The maximum operating temperature of commercial nanofiltration membrane is often given with 50 – 60 ºC based on the three-layer structure of membranes consisting of a polyester or polypropylene support paper with a polysulphone support layer and an active layer of polyamide. Operatin

In chapter 5, Juan Carlos Mendoza Collazos presents an overview of a new approach to signification, known as agentive semiotics, that “links achievements of logic, phenomenology and cognitive sciences” (Niño 2015). As the author states, this clearly aligns this approach with cognitive semiotics. Similarly, agentive semiotics is influenced by enactivism, though it takes a more specific stand on the

Objetos como los artefactos no interactúan con los usuarios, no significan por sí mismos y no comunican. Estas premisas tienen implicaciones en la forma en que se asumen las actuales tendencias del diseño que dan por sentado, sin mayor atención, las interacciones entre el artefacto y los usuarios, olvidando que dichas interacciones fueron formuladas en un contexto cibernético y no en un contexto s