Integrating bioinfomatics and physiology to describe genetic affects in complez polygenic diseases Type 2 diabetes mellitus (T2DM) results from interaction between genetic and environmental factors. The worldwide prevalence of T2DM is increasing rapidly due to reduction in physical activity, increase in dietary intake, and the aging of the population. This thesis has focused on dissecting the gene

https://www.ludc.lu.se/education-training/theses/theses-2009/hemang-parikh - 2025-08-05

Exploring the Grey Zone between Type 1 and Type 2 Diabetes T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA),

https://www.ludc.lu.se/education-training/theses/theses-2009/ekaterine-bakhtadze - 2025-08-05

Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify poss

https://www.ludc.lu.se/education-training/theses/theses-2010/magnus-ekelund - 2025-08-05

Regulation of Glucagon Secretion from pancreatic alpha cells Glucagon secreted by pancreatic α-cells plays an important role in the regulation of blood glucose. In this thesis, different techniques such as electrophysiology, immunohistochemistry and hormone secretion assay were combined to explore the mechanisms by which glucagon secretion is regulated. Like pancreatic β-cells, which produce insul

https://www.ludc.lu.se/education-training/theses/theses-2010/yang-zhang-de-marinis - 2025-08-05

Molecular Etiology of Graves´ Disease and Associated Ophthalmopathy Graves' disease (GD) is a complex autoimmune disorder characterized by hyperthyroidism and diffuse goitre. 25-50% of the patients with GD develop eye symptoms, Graves' ophthalmopathy (GO). The overall aim of this thesis was to explore the molecular etiology of GD and GO. By studying gene expression in Studies I, III, and IV, we de

https://www.ludc.lu.se/education-training/theses/theses-2010/tereza-planck - 2025-08-05

The Role of Genetic Variation and DNA Methylation in Human Glucose Metabolism and Type 2 Diabetes The incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thes

https://www.ludc.lu.se/education-training/theses/theses-2010/tina-ronn - 2025-08-05

Consultant

https://www.ludc.lu.se/innovation/innovation-board/lars-hedbys - 2025-08-05

Member of the Hjelt Foundation, Geneva

https://www.ludc.lu.se/innovation/innovation-board/paola-hjelt - 2025-08-05

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https://www.ludc.lu.se/innovation/innovation-board/sibylle-lenz - 2025-08-05

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https://www.ludc.lu.se/innovation/innovation-board/peter-morck-eriksen - 2025-08-05

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https://www.ludc.lu.se/innovation/innovation-board/rolf-ehrnstrom - 2025-08-05

23 October 2025 09:00 to 17:00 | Conference SciLifeLab Lund Day 2025! Welcome to SciLifeLab Lund Day 2025! Join us for a dynamic day that brings together researchers, technology platforms, and strategic research initiatives to spotlight the powerful synergies driving life science forward in southern Sweden. This year’s program will feature:A showcase of SciLifeLab’s cutting-edge technologies and n

https://www.ludc.lu.se/calendar/scilifelab-lund-day-2025-accelerating-strategic-research-through-collaboration-infrastructure-and - 2025-08-05

13 November 2025 15:00 to 19:00 | Lecture/talk Världsdiabetesdagen Skåne som i år arrangeras torsdagen den 13 november sätter fokus på hälsa och välbefinnande vid diabetes. Foto: Kennet Ruona Vilken betydelse har kost, träning och diabetesteknik för den som lever med diabetes? Världsdiabetesdagen Skåne som arrangeras torsdagen den 13 november sätter fokus på hälsa och välbefinnande vid diabetes. A

https://www.ludc.lu.se/calendar/varldsdiabetsdagen-skane-2025-halsa-och-valbefinnande-vid-diabetes - 2025-08-05

19 September 2025 14:00 to 15:00 | Seminar Join the EXODIAB webinars for lectures in diabetes research at Lund University and Uppsala University. The webinars are arranged by EXODIAB (Excellence of Diabetes Research in Sweden), a joint strategic research initiative in the diabetes area by Lund University and Uppsala University. These webinars are aimed at diabetes researchers within EXODIAB and di

https://www.ludc.lu.se/calendar/exodiab-webinar-3 - 2025-08-05

17 October 2025 14:00 to 15:00 | Seminar Join the EXODIAB webinars for lectures in diabetes research at Lund University and Uppsala University. The webinars are arranged by EXODIAB (Excellence of Diabetes Research in Sweden), a joint strategic research initiative in the diabetes area by Lund University and Uppsala University. These webinars are aimed at diabetes researchers within EXODIAB and diab

https://www.ludc.lu.se/calendar/exodiab-webinar-4 - 2025-08-05

21 November 2025 14:00 to 15:00 | Seminar Join the EXODIAB webinars for lectures in diabetes research at Lund University and Uppsala University. The webinars are arranged by EXODIAB (Excellence of Diabetes Research in Sweden), a joint strategic research initiative in the diabetes area by Lund University and Uppsala University. These webinars are aimed at diabetes researchers within EXODIAB and dia

https://www.ludc.lu.se/calendar/exodiab-webinar-5 - 2025-08-05

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https://www.ludc.lu.se/innovation/innovation-board/lars-grundemar - 2025-08-05

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https://www.ludc.lu.se/innovation/innovation-board/christine-widstrand - 2025-08-05

https://www.ludc.lu.se/about-us-old - 2025-08-05

Lund University Diabetes Centre, LUDC, is a consortium of research groups at Lund University dedicated to unravelling the pathogenesis and treatment of diabetes mellitus. LUDC started July 1st 2006 when selected for funding by the Swedish Research Council (Vetenskapsrådet) in fierce national competition, as a part of the call for applications for Linneaus grants. We are active in several different

https://www.ludc.lu.se/about-us/welcome-lund-university-diabetes-centre - 2025-08-05