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We report the identification and molecular characterization of tena*, a Drosophila gene located at 11A6-9 on the X-chromosome. The deduced protein of 782 amino acids contains eight tenascin-type EGF-like repeats not described in Drosophila before, but lacks the fibronectin type III repeats and the fibrinogen homology present in the vertebrate tenascin molecules. Tena codes for a large transcript w
Introduction: Copeptin is the stable surrogate marker of vasopressin (VP), which is released in response to elevated plasma osmolality or low blood pressure. Elevated plasma copeptin levels are associated with higher risk of insulin resistance-related disorders, such as type 2 diabetes (T2DM), metabolic syndrome (MS), and cardiovascular disease, and experimental reduction of circulating VP levels
AbstractBlind, I. 2015. Essays on Urban Economics. Economic studies 153. xii+199 pp. Uppsala:Department of Economics. ISBN 978-91-85519-60-6.This thesis consists of four self-contained essays.Essay 1 (with Olof Åslund and Matz Dahlberg): In this essay we investigate the impact ofcommuter train access on individual labor market outcomes. Our study considers the exogenousintroduction of a commuter t
cDNA clones encoding the catalytic subunit and the 65-kDa regulatory subunit of protein phosphatase 2A (PR65) from Drosophila melanogaster have been isolated by homology screening with the corresponding human cDNAs. The Drosophila clones were used to analyze the spatial and temporal expression of the transcripts encoding these two proteins. The Drosophila PR65 cDNA clones contained an open reading
A model of the trans-regulation of the Drosophila pair-rule segmentation gene, paired (prd), has been derived from the observed alterations in the distribution of prd transcripts during early embryogenesis in single and double pair-rule mutants. Important aspects of the model include the following features and implications: (i) The regulation of prd is subject to a regulatory hierarchy among pair-
Two new paired domain genes of Drosophila, Pox meso and Pox neuro, are described. In contrast to the previously isolated paired domain gnees, paired and gooseberry, which contain both a paired and a homeodomain (PHox genes), Pox meso and Pox neuro possess no homeodomain. Evidence suggesting that the new genes encode tissue-specific transcriptional factors and belong to the same regulatory cascade
The gooseberry (gsb) locus contains two closely linked genes, BSH9 and BSH4, which are structurally related to each other and to the paired (prd) gene. Sequence analysis of genomic DNA and cDNA shows that BSH9 and BSH4 can encode proteins of 427 and 452 amino acids, respectively. The structural homology between these two putative proteins and the prd protein consists essentially of two domains for
We propose a technique to generate non-projective word orders in an efficient statistical linearization system. Our approach predicts liftings of edges in an unordered syntactic tree by means of a classifier, and uses a projective algorithm for tree linearization. We obtain statistically significant improvements on six typologically different languages: English, German, Dutch, Danish, Hungarian, a
Extending our search for homologous domains of the Drosophila paired gene, two closely linked genes at the gooseberry locus have been isolated. Both genes are expressed with a single segment periodicity but with different spatial and temporal expression patterns. While the transcripts of one gene appear earlier and are equally distributed between ectoderm and mesoderm, those of the second gene acc
The sequence of paired, a pair-rule gene required for segmentation in Drosophila, is presented. A search for genes with domains homologous to the paired gene was initiated and three homologues from a set of 12 were characterized with respect to temporal or spatial expression and sequence homologies. All four are transcribed in early development, one in the oocyte and during cleavage stages in the
We have cloned the paired gene of Drosophila melanogaster, a pair-rule gene required for the establishment of proper segmentation. The transcriptional pattern in young embryos shows developmental polarities along the antero-posterior and dorso-ventral axes. Transcripts, initially expressed with a double-segment periodicity, switch to a single-segment repeat during syncytial blastoderm.
This paper describes the IMS-SZEGED-CIS contribution to the SPMRL 2013 Shared Task. We participate in both the constituency and dependency tracks, and achieve state-of-theart for all languages. For both tracks we make significant improvements through high quality preprocessing and (re)ranking on top of strongbaselines. Our system came out first for both tracks.
The PHO84 and PHO89 genes of Saccharomyces cerevisiae encode two high- affinity phosphate cotransporters of the plasma membrane. Hydropathy analysis suggests a secondary structure arrangements of the proteins in 12 transmembrane domains. The derepressible Pho84 and Pho89 transporters appear to have characteristic similarities with the phosphate transporters of Neurospora crassa. The Pho84 protein
Teneurins were first discovered and published in 1993 and 1994, in Drosophila melanogaster as Ten-a and Ten-m. They were initially described as cell surface proteins, and as pair-rule genes. Later, they proved to be type II transmembrane proteins, and not to be pair-rule genes. Ten-m might nonetheless have had an ancestral function in clock-based segmentation as a Ten-m oscillator. The turn of the
In the preceding paper [D. Hobbs, J. Hafner, and D. Spišák, Phys. Rev. B 68, 014407 (2003)], we have started an ab initio spin-density-functional study of the complex structural and magnetic phase behaviors of Mn by a detailed investigation of α−Mn. It was shown that the complex crystalline and noncollinear antiferromagnetic structures are the results of the conflicting tendencies to maximize simu
Large-scale linguistically annotated corpora have played a crucial role in advancing the state of the art of key natural language technologies such as syntactic, semantic and discourse analyzers, and they serve as training data as well as evaluation benchmarks. Up till now, however, most of the evaluation has been done on monolithic corpora such as the Penn Treebank, the Proposition Bank. As a res
