Popular Abstract in Swedish I avhandlingen studeras Matrix MetalloProteinase-26 (MMP-26) och Tissue Inhibitor of MetalloProteinases-4 (TIMP-4) i normalt, hyperplastiskt och malignt endometrium. Just detta protease/hämmarpar kan potentiellt vara av mycket stort intresse vid implantationsprocessen. Trofoblastvävnad från såväl humant som murint embryo producerar proMMP-9. Aktivt MMP-9 (Gelatinase B)The aim of the thesis was to study matrix metalloproteinase-26 (MMP-26) and tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium. Most importantnly, both these molecules may be ivolved in the implantation process. Trophoblast tissue from human as well as mouse embryos produces pro-MMP-9. Active MMP-9 (gelatinase B) is a proteolytic enzyme with a bro

It has been shown that the combination of benzylamine or tyramine and low concentrations of vanadate markedly stimulates glucose transport in rat adipocytes by a mechanism that requires semicarbazide-sensitive amine oxidase (SSAO) activity and H(2)O(2) formation. Here we have further analysed the insulin-like effects of the combination of SSAO substrates and vanadate and we have studied the signal

trans-PtCl2(dms)(2) (dms is dimethyl sulfide) crystallizes in the space group P2(1)/n and adopts the molecular point group C-i, which is the most frequently occurring point group for trans-PtX2L2 complexes (78%), as observed in the Cambridge Structural Database (CSD; 2005 release), followed by C-1 (16%). Density functional theory calculations show that the observed geometry for trans- PtCl2(dms)(2

Abstract is not available

Some elements have toxic effects on the human body and there is thus a need to control their levels in human organs and tissues. Moreover, it is important to increase our knowledge of relationships between observable toxic effects and element concentrations in man and his environment. Monitoring and basic occupational and environmental research rely on measurements directly in humans as well as sa

Artikeln bygger på gästföreläsningar i Heidelberg och Helsingfors. Den är en förstudie till ett av Vetenskapsrådet stött projekt om tillämpningen av de tyska raslagarna vid hindersprövning på pastorsämbetena i Sverige. Tillämpningen byggde på en internationell privaträttslig konvention från 1902. I Nederländerna, med samma rättsläge, tillämpades raslagarna endast på tyska medborgare, men i Sverige

Popular Abstract in Swedish Denna avhandling innehåller en huvudstudie och en delstudie. Syftet med huvudstudien var att följa upp en grupp ungdomar som hade blivit diagnostiserade med uppförandestörning (n=351) i det unga vuxenlivet. Delstudiens syfte var att ifrågasätta och klargöra frågeformuläret KASAM-29 och dess förhållande till den salutogena teorin. I avhandlingen användes olika utfallsvarThis dissertation consists of a primary and a secondary study. The aim of the primary study is to follow-up a group of juveniles diagnosed with conduct disorder (n=351) into adulthood. The secondary study's aim is to question, clarify and attach the questionnaire SOC-29 to the salutogenic theory.In the dissertation different outcomes and outcome measurements are fomulated and discussed. Two perspe

Eosinophils are considered essential in the pathogenesis of allergy. Reduced eosinophil apoptosis is considered to be a key element in the formation of eosinophilia in allergic conditions. Antihistamines are widely used in the treatment of allergic disorders, but their effects on eosinophil apoptosis are poorly understood. The histamine HI-receptor antagonist, ketotifen, is available orally and as

Swedish guidelines for thrombosis risk estimation and thrombosis prophylaxis in relation to pregnancy are based on risk factors with a 5-fold increased risk of thrombosis or some multiple thereof. The risk factors are added together forming a risk score, where by risk score 1 is associated with a 5-fold increased risk, risk score 2 with a 25-fold increased risk, etc. The absolute risk of thrombosi

The structures of 2(diphenylphosphino)acetophenone and bis(2(diphenyl phosphino)acetophenone)palladium(II)bistriflate have been determined by X-ray crystallography. The ligand is of interest because its P,O donor set combines the hard and soft properties. In the Pd-complex, which was prepared by treating tetrakisacetonitrile-palladium-bistriflate with 2-(diphenylphosphino)acetophenone in dichlorom

A numerical model is presented that simulates sediment transport and profile response produced by overwash of dunes by wave runup. Transport formulas are derived for the different regions of the subaerial portion of the beach covering the swash zone, beach and dune crest, and region landward of the crest. After calculating the distribution of the cross-shore sediment transport rate, profile respon

The effect of the extent of electron conjugation on the primary photophysics in semiconducting polymers is reported. A rapid depolarization of photoluminescence and transient absorption, which indicates a reorientation of the transition dipole moment by ~30° on a sub-100 fs time scale, is observed in the fully conjugated polymer poly[2-(2'-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene] (MEH-PPV).

This study investigated whether the relation between implicit and explicit homonegativity measures is affected by self-presentation concerns, since previous research in this area has been inconclusive. In Experiment 1, 70 high-school students made evaluative ratings of pictures of homosexual and heterosexual couples. Self-presentation was manipulated by either instructing participants that the stu